2017-11-30Author:adminpraise:1
TP53 (Tumor Protein P53) encodes a tumor suppressor protein with transcriptional activation, DNA binding and oligomerization domains. The protein can respond to diverse cellular stress to regulate the expression of the target gene, and induce cell cycle arrest, apoptosis, senescence, DNA repair or metabolic changes. In cell cycle regulation, it acts as a trans-activator that negatively regulates cell division by controlling a set of genes required for this process. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. The relevant pathways are DNA damage and ovarian tumor domain proteases.
Cat. No. |
Product Name |
Reactivity |
Mouse |
||
Rat |
||
Human, Monkey |
||
Human, Mouse, Rat, Monkey |
||
Human, Mouse, Rat |
||
Human, Monkey |
||
Human, Monkey |
||
Human, Mouse, Rat |
||
Human, Mouse, Rat |
||
Human, Rat, Monkey |
||
Human |
||
Human |
||
Human, Mouse, Rat |
||
Human |
||
Human |
||
Human, Monkey |
||
Human, Mouse, Rat, Monkey |
||
Human |
||
Human |
||
Human |
||
Human |
||
Human, Mouse, Rat |
||
Human |
||
Human |
||
Human |
||
Human |
||
Human |
||
Human |
||
Human, Rat |
||
Human, Mouse, Rat, Monkey |
||
Human |
||
Human |
||
Human, Monkey |
||
Human, Monkey |
||
Human, Monkey |
||
Human, Mouse, Rat |
||
Human |
||
Human, Mouse, Rat |
||
Human, Mouse, Rat |
||
Human |
||
Human |
||
Human |
Prev: TNF
Next: This is the Last One.