Apoptosis is a complex and active death, involving the activation, expression and regulation of a series of genes.
When apoptosis occurs, a series of apoptotic processes are programmed, such as phosphatidylserines valgus outside of the cell membrane, mitochondrial membrane ΔΨm changes, caspase activation, DNA fragmentation and so on.
Different methods of apoptosis research
Apoptotic event line
Abnormal apoptotic mechanism can cause cells to lose control, which is closely related to the occurrence and development of many diseases such as tumors. Accurate detection of apoptotic cells is essential in the apoptosis study.
Comparing to the conventional MTT method, Cell Counting Kit 8 (WST-8 / CCK8) is a more sensitive and non-radioactive colorimetric method for detecting the number of living cells in cell viability, proliferation or cytotoxicity test. Elabscience® developed an Enhanced CCK8 kit with much higher sensitivity and much wider linearity.
View Elabscience®Cell Viability/Proliferation/Cytotoxicity Detection Products
Cell cycle refers to the whole process from the end of one mitosis to the end of the next. DNA detection can be used to reflect the status of each phase of the cell cycle. Elabscience® applies the characteristics of DNA binding with fluorescent dyes (such as propidium iodide PI), then measure the DNA amount according to fluorescence intensity.
View Elabscience® Cell Cycle Assay Kit
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