The main functions of the liver include detoxification, metabolism, bile secretion, hemopoietic blood storage and regulation of circulating blood volume, immune defense and regeneration. The indicators of liver biomarkers are mainly divided into four categories, as shown in the following chart：
1. Hepatocyte injury: serum alanine aminotransferase (ALT), serum glutamic-oxaloacetic aminotransferase (AST), alkaline phosphatase (ALP), γ-glutamyl transpeptidase (γ-GT), lactate dehydrogenase (LDH), etc.
2. Liver excretory function: total bilirubin, direct bilirubin and indirect bilirubin, etc.
Liver reserve function: total protein (TP), albumin, (ALB), immunoglobulin G, prothrombin time (PT), etc.
3. Hepatic interstitial changes: serum protein electrophoresis, γ-globulin, hyaluronidase (HA), lamellae (LN), type Ⅲ procollagen peptide and collagen Ⅳ, etc.
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