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Rat TNF-α(Tumor Necrosis Factor Alpha) ELISA Kit

Citations(656)Uniprot : P16599

Cat.No.:E-EL-R2856
Reactivity: Rat

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96T
48T
24T
96T*5
96T*10

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Product Details

Properties

Assay type	Sandwich-ELISA
Format	96T/48T
Assay time	3.5h
Detection range	15.63-1000 pg/mL
Sensitivity	9.38 pg/mL
Sample type &Sample volume	serum, plasma and other biological fluids; 100μL
Specificity	This kit recognizes Rat TNF-α in samples. No significant cross-reactivity or interference between Rat TNF-α and analogues was observed.
Reproducibility	Both intra-CV and inter-CV are < 10%.
Application	This ELISA kit applies to the in vitro quantitative determination of Rat TNF-α concentrations in serum, plasma and other biological fluids.

Test Principle

This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Rat TNF-α. Standards or samples are added to the micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Rat TNF-α and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Rat TNF-α, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm ± 2 nm. The OD value is proportional to the concentration of Rat TNF-α. You can calculate the concentration of Rat TNF-α in the samples by comparing the OD of the samples to the standard curve.

Kit components & Storage

An unopened kit can be stored at 2-8℃ for 1 month. If the kit is not supposed to be used within 1 month, store the components separately according to the following conditions once the kit is received.

Item	Specifications	Storage
Micro ELISA Plate(Dismountable)	96T: 8 wells ×12 strips 48T: 8 wells ×6 strips	-20℃, 6 months
Reference Standard	96T: 2 vials 48T: 1 vial
Concentrated Biotinylated Detection Ab (100×)	96T: 1 vial, 120 μL 48T: 1 vial, 60 μL
Concentrated HRP Conjugate (100×)	96T: 1 vial, 120 μL 48T: 1 vial, 60 μL	-20℃(Protect from light), 6 months
Reference Standard & Sample Diluent	1 vial, 20 mL	2-8°C, 6 months
Biotinylated Detection Ab Diluent	1 vial, 14 mL
HRP Conjugate Diluent	1 vial, 14 mL
Concentrated Wash Buffer (25×)	1 vial, 30 mL
Substrate Reagent	1 vial, 10 mL	2-8℃(Protect from light)
Stop Solution	1 vial, 10 mL	2-8°C
Plate Sealer	5 pieces
Manual	1 copy
Certificate of Analysis	1 copy

Technical Data

Precision

Intra-assay Precision (Precision within an assay): 3 samples with low, mid range and high level Rat TNF-α were tested 20 times on one plate, respectively.
Inter-assay Precision (Precision between assays): 3 samples with low, mid range and high level Rat TNF-α were tested on 3 different plates, 20 replicates in each plate.

	Intra-assay Precision			Inter-assay Precision
Sample	1	2	3	1	2	3
n	20	20	20	20	20	20
Mean (pg/mL)	42.74	109.13	414.25	49.50	115.50	436.41
Standard deviation	2.30	5.13	16.78	2.53	5.51	23.48
CV (%)	5.38	4.70	4.05	5.11	4.77	5.38

Recovery

The recovery of Rat TNF-α spiked at three different levels in samples throughout the range of the assay was evaluated in various matrices.

Sample Type	Range (%)	Average Recovery (%)
Serum(n=8)	87-99	94
EDTA plasma (n=8)	102-110	105
Cell culture media (n=8)	98-104	101

Linearity

Samples were spiked with high concentrations of Rat TNF-α and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

Target Information

Database Links	SwissProt: P16599
Synonyms	DIF, TNF-alpha, TNFA, TNFSF2
Research Area	Signal transduction, Metabolism, Cancer, Immunology, Microbiology, Cardiovascular

Assay Procedures

	1. Add 100μL standard or sample to the wells. Incubate for 90 min at 37°C
	2. Discard the liquid, immediately add 100μL Biotinylated Detection Ab working solution to each well. Incubate for 60 min at 37°C
	3. Aspirate and wash the plate for 3 times
	4. Add 100μL HRP conjugate working solution. Incubate for 30 min at 37°C. Aspirate and wash the plate for 5 times
	5. Add 90μL Substrate Reagent. Incubate for 15 min at 37°C
	6. Add 50μL Stop Solution
	7. Read the plate at 450nm immediately. Calculation of the results

Citations

CRITICAL CARE (2022) IF: 19.334
Individualizing mechanical ventilation: titration of driving pressure to pulmonary elastance through Young’s modulus in an acute respiratory distress syndrome animal model

DOI: 10.1186/s13054-022-04184-w

PMID: 36258235
Sample: bronchoalveolar lavages (BAL)
BIOMATERIALS (2021) IF: 12.479
Polyphenol-assisted facile assembly of bioactive nanoparticles for targeted therapy of heart diseases

DOI: 10.1016/j.biomaterials.2021.120952

PMID: 34147720
Sample: heart
Advanced Healthcare Materials (2022) IF: 11.092
Spatiotemporal regulation of the bone immune microenvironment via dam-like biphasic bionic periosteum for bone regeneration

DOI: 10.1002/adhm.202201661

PMID: 36189833
Sample: BMSCs
Advanced Healthcare Materials (2022) IF: 11.092
An Acellular Scaffold Facilitates Endometrial Regeneration and Fertility Restoration via Recruiting Endogenous Mesenchymal Stem Cells

DOI: 10.1002/adhm.202201680

PMID: 36049781
Sample: Uterine
Applied Materials Today (2022) IF: 10.041
Preclinical studies of an automated radiolabeled microcarriers for radiosynovectomy of inflammatory joint disease

DOI: 10.1016/j.apmt.2022.101571

Sample: Serum
JOURNAL OF NANOBIOTECHNOLOGY (2022) IF: 10.435
A novel hierarchical biofunctionalized 3D-printed porous Ti6Al4V scaffold with enhanced osteoporotic osseointegration through osteoimmunomodulation

DOI: 10.1186/s12951-022-01277-0

PMID: 35123501
Sample: rat bone marrow mesenchymal stem cells (rBMSCs)
CHEMISTRY OF MATERIALS (2022) IF: 10.508
Biomechanically Compatible Hydrogel Bioprosthetic Valves

DOI: 10.1021/acs.chemmater.2c01300

Sample: blood
ACS Applied Materials & Interfaces (2021) IF: 9.2289
Self-Assembled pH-Sensitive Polymeric Nanoparticles for the Inflammation-Targeted Delivery of Cu/Zn-Superoxide Dismutase

DOI: 10.1021/acsami.1c03589

PMID: 33764751
Sample: Plasma
CELLULAR AND MOLECULAR LIFE SCIENCES (2016) IF: 9.2609
toxin B

DOI: 10.1007/s00018-016-2426-4

Sample: Cell culture supernatant
Journal of Neuroinflammation (2023) IF: 9.587
Morinda officinalis oligosaccharides mitigate depression-like behaviors in hypertension rats by regulating Mfn2-mediated mitophagy

DOI: 10.1186/s12974-023-02715-y

Sample: brain,serum
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022) IF: 8.025
Structural elucidation and anti-neuroinflammatory activity of Polygala tenuifolia polysaccharide

DOI: 10.1016/j.ijbiomac.2022.08.161

PMID: 36037912
Sample: serum
Stem Cell Research & Therapy (2022) IF: 8.0790
Embryonic stem cell-derived mesenchymal stem cells alleviate skeletal muscle injury induced by acute compartment syndrome

DOI: 10.1186/s13287-022-03000-0

PMID: 35841081
Sample: serum
AMERICAN JOURNAL OF TRANSPLANTATION (2022) IF: 8.086
Machine perfusion combined with antibiotics prevents donor-derived infections caused by multidrug-resistant bacteria

DOI: 10.1111/ajt.17032

PMID: 35303398
Sample: serum
Journal of Neuroinflammation (2021) IF: 8.3219
Rifaximin-mediated gut microbiota regulation modulates the function of microglia and protects against CUMS-induced depression-like behaviors in adolescent rat

DOI: 10.1186/s12974-021-02303-y

PMID: 34736493
Sample: brain
Journal of Neuroinflammation (2020) IF: 8.3219
Microglia induce the transformation of A1/A2 reactive astrocytes via the CXCR7/PI3K/Akt pathway in chronic post-surgical pain

DOI: 10.1186/s12974-020-01891-5

PMID: 32665021
Sample: Tissue homogenate
Journal of Neuroinflammation (2021) IF: 8.3219
EETs/sEHi alleviates nociception by blocking the crosslink between endoplasmic reticulum stress and neuroinflammation in a central poststroke pain model

DOI: 10.1186/s12974-021-02255-3

PMID: 34530836
Sample: brain
BRITISH JOURNAL OF PHARMACOLOGY (2022) IF: 8.74
Resveratrol attenuates behavioural impairment associated with learning and memory in HFD-STZ induced diabetic rats

DOI: 10.1111/bph.15895

Sample: plasma,brain
International Journal of Nanomedicine (2023) IF: 7.033
Nano Parthenolide Improves Intestinal Barrier Function of Sepsis by Inhibiting Apoptosis and ROS via 5-HTR2A

DOI: 10.2147/IJN.S394544

Sample: blood
CNS Neuroscience & Therapeutics (2022) IF: 7.035
Effects of intraperitoneal injection of lipopolysaccharide-induced peripheral inflammation on dopamine neuron damage in rat midbrain

DOI: 10.1111/cns.13906

PMID: 35789066
Sample: blood
Oxidative Medicine and Cellular Longevity (2023) IF: 7.31
Ferroptosis in Rat Lung Tissue during Severe Acute Pancreatitis-Associated Acute Lung Injury: Protection of Qingyi Decoction

DOI: 10.1155/2023/5827613

Sample: serum
Oxidative Medicine and Cellular Longevity (2022) IF: 7.31
Change in Oxidative Stress and Mitochondrial Dynamics in Response to Elevated Cold-Inducible RNA-Binding Protein in Cardiac Surgery-Associated Acute Kidney Injury

DOI: 10.1155/2022/3576892

PMID: 35855864
Sample: serum
BIOMEDICINE & PHARMACOTHERAPY (2022) IF: 7.419
The mechanism of formononetin/calycosin compound optimizing the effects of temozolomide on C6 malignant glioma based on metabolomics and network pharmacology

DOI: 10.1016/j.biopha.2022.113418

PMID: 36076540
Sample: C6 glioma xenogfrat tissue
BIOMEDICINE & PHARMACOTHERAPY (2023) IF: 7.419
Quince extract resists atherosclerosis in rats by down-regulating the EGFR/PI3K/Akt/GSK-3β pathway

DOI: 10.1016/j.biopha.2023.114330

Sample: serum
Cells (2022) IF: 7.666
Forskolin, an Adenylcyclase/cAMP/CREB Signaling Activator Restoring Myelin-Associated Oligodendrocyte Destruction in Experimental Ethidium Bromide Model of Multiple Sclerosis

DOI: 10.3390/cells11182771

PMID: 36139346
Sample: brain tissue
Antioxidants (2022) IF: 7.675
Mangosteen Pericarp Extract Supplementation Boosts Antioxidant Status via Rebuilding Gut Microbiota to Attenuate Motor Deficit in 6-OHDA-Induced Parkinson’s Disease

DOI: 10.3390/antiox11122396

Sample: plasma
Antioxidants (2022) IF: 7.675
Comparable Benefits of Stingless Bee Honey and Caffeic Acid in Mitigating the Negative Effects of Metabolic Syndrome on the Brain

DOI: 10.3390/antiox11112154

PMID: 36358526
Sample: brain tissue
FOOD AND CHEMICAL TOXICOLOGY (2021) IF: 6.025
Reactive astrocytes induced by 2-chloroethanol modulate microglia polarization through IL-1β, TNF-α, and iNOS upregulation

DOI: 10.1016/j.fct.2021.112550

PMID: 34517076
Sample: astrocyte
Frontiers in Cardiovascular Medicine (2021) IF: 6.05
Long Non-coding RNA N1LR Protects Against Myocardial Ischemic/Reperfusion Injury Through Regulating the TGF-β Signaling Pathway

DOI: 10.3389/fcvm.2021.654969

PMID: 34485393
Sample: H9c2 cell
Frontiers in Cellular and Infection Microbiology (2022) IF: 6.073
Liujunanwei decoction attenuates cisplatin-induced nausea and vomiting in a Rat-Pica model partially mediated by modulating the gut micsrobiome

DOI: 10.3389/fcimb.2022.876781

PMID: 36061858
Sample: jejunum tissue,medulla oblongata tissue
Frontiers in Cellular and Infection Microbiology (2022) IF: 6.073
Changes in intestinal microflora and its metabolites underlie the cognitive impairment in preterm rats

DOI: 10.3389/fcimb.2022.945851

PMID: 36061856
Sample: serum
Frontiers in Cell and Developmental Biology (2022) IF: 6.081
Prevention of mortality in acute lung injury induced by oleic acid: Application of polyherbal decoction (bronco T)

DOI: 10.3389/fcell.2022.1003767

PMID: 36313556
Sample: lung tissue
American Journal of Cancer Research (2021) IF: 6.166
Adamantane-linked isothiourea derivatives suppress the growth of experimental hepatocellular carcinoma via inhibition of TLR4-MyD88-NF-κB signaling

PMID: 33575076
Sample: Tissue homogenate(liver tissue),Serum
BRAIN BEHAVIOR AND IMMUNITY (2019) IF: 6.17
High mobility group box-1 mediates hippocampal inflammation and contributes to cognitive deficits in high-fat high-fructose diet-induced obese rats

DOI: 10.1016/j.bbi.2019.08.007

Sample: plasma，brain
MOLECULAR NEUROBIOLOGY (2017) IF: 6.19
Modulatory Role of Nurr1 Activation and Thrombin Inhibition in the Neuroprotective Effects of Dabigatran Etexilate in Rotenone-Induced Parkinson’s Disease in Rats

DOI: 10.1007/s12035-017-0636-x

Sample: Tissue homogenate
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022) IF: 6.208
Ameliorative Effects of a Rhenium (V) Compound with Uracil-Derived Ligand Markers Associated with Hyperglycaemia-Induced Renal Dysfunction in Diet-Induced Prediabetic Rats

DOI: 10.3390/ijms232315400

Sample: kidney
Arabian Journal of Chemistry (2022) IF: 6.212
Calotropis procera (Aiton) seeds fixed oil: Physicochemical analysis, GC-MS profiling and evaluation of its in-vivo anti-inflammatory and in-vitro antiparasitic activities

DOI: 10.1016/j.arabjc.2022.104085

Sample: Serum
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2019) IF: 6.291
Soybean isoflavones prevent atrazine-induced neurodegenerative damage by inducing autophagy

DOI: 10.1016/j.ecoenv.2019.110065

PMID: 31869719
Sample: Tissue homogenate
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2021) IF: 6.291
Effects of cadmium on organ function, gut microbiota and its metabolomics profile in adolescent rats

DOI: 10.1016/j.ecoenv.2021.112501

PMID: 34265528
Sample: serum
Antioxidants (2022) IF: 6.313
Cisplatin-Induced Reproductive Toxicity and Oxidative Stress: Ameliorative Effect of Kinetin

DOI: 10.3390/antiox11050863

PMID: 35624727
Sample: testicular tissue
Pharmaceutics (2022) IF: 6.321
Reparative Efficacy of Liposome-Encapsulated Oleanolic Acid against Liver Inflammation Induced by Fine Ambient Particulate Matter and Alcohol in Mice

DOI: 10.3390/pharmaceutics14051108

PMID: 35631694
Sample: LX-2 cell
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2023) IF: 6.51
Therapeutic potential of cationic bilosomes in the treatment of carrageenan-induced rat arthritis via fluticasone propionate gel

DOI: 10.1016/j.ijpharm.2023.122776

Sample: joint
Pharmaceutics (2023) IF: 6.525
Immunomodulatory Effect of Novel Electrospun Nanofibers Loaded with Doxycycline as an Adjuvant Treatment in Periodontitis

DOI: 10.3390/pharmaceutics15020707

Sample: Blood
BIOMEDICINE & PHARMACOTHERAPY (2021) IF: 6.53
Water-soluble alkaloids extracted from Aconiti Radix lateralis praeparata protect against chronic heart failure in rats via a calcium signaling pathway

DOI: 10.1016/j.biopha.2020.111184

PMID: 33418305
Sample: Plasma
BIOMEDICINE & PHARMACOTHERAPY (2018) IF: 6.53
Trichosanthes kirilowii lectin ameliorates streptozocin-induced kidney injury via modulation of the balance between M1/M2 phenotype macrophage

DOI: 10.1016/j.biopha.2018.10.060

PMID: 30396096
Sample: Serum
BIOMEDICINE & PHARMACOTHERAPY (2020) IF: 6.53
Tetramethylpyrazine attenuates endotoxin-induced retinal inflammation by inhibiting microglial activation via the TLR4/NF-κB signalling pathway

DOI: 10.1016/j.biopha.2020.110273

PMID: 32460188
Sample: Cell culture supernatant
BIOMEDICINE & PHARMACOTHERAPY (2021) IF: 6.53
Pharmacological evaluation of continentalic acid for antidiabetic potential

DOI: 10.1016/j.biopha.2021.111411

PMID: 33711550
Sample: Whole Blood
BIOMEDICINE & PHARMACOTHERAPY (2021) IF: 6.53
Omega-3 fatty acid rescues ischaemia/perfusion-induced testicular and sperm damage via modulation of lactate transport and xanthine oxidase/uric acid signaling

DOI: 10.1016/j.biopha.2021.111975

PMID: 34343894
Sample: Testicular
BIOMEDICINE & PHARMACOTHERAPY (2021) IF: 6.53
L-ergothioneine and its combination with metformin attenuates renal dysfunction in type-2 diabetic rat model by activating Nrf2 antioxidant pathway

DOI: 10.1016/j.biopha.2021.111921

PMID: 34346315
Sample: kidney
BIOMEDICINE & PHARMACOTHERAPY (2021) IF: 6.53
Kolaviron attenuates cardiovascular injury in fructose-streptozotocin induced type-2 diabetic male rats by reducing oxidative stress, inflammation, and improving cardiovascular risk markers

DOI: 10.1016/j.biopha.2021.112323

PMID: 34656062
Sample: plasma
BIOMEDICINE & PHARMACOTHERAPY (2021) IF: 6.53
Hippocampus kuda protein hydrolysate improves male reproductive dysfunction in diabetic rats

DOI: 10.1016/j.biopha.2021.111760

PMID: 34052566
Sample: Tissue homogenate,Plasma
BIOMEDICINE & PHARMACOTHERAPY (2022) IF: 6.53
Glutamine restores testicular glutathione-dependent antioxidant defense and upregulates NO/cGMP signaling in sleep deprivation-induced reproductive dysfunction in rats

DOI: 10.1016/j.biopha.2022.112765

PMID: 35247715
Sample: Testicular,epididymal
BIOMEDICINE & PHARMACOTHERAPY (2022) IF: 6.53
Glutamine prevents upregulation of NF-kB signaling and caspase 3 activation in ischaemia/reperfusion-induced testicular damage: An animal model

DOI: 10.1016/j.biopha.2022.113056

PMID: 35658227
Sample: testicular tissue
BIOMEDICINE & PHARMACOTHERAPY (2020) IF: 6.53
Gastroprotective effect of gallic acid against ethanol-induced gastric ulcer in rats: Involvement of the Nrf2/HO-1 signaling and anti-apoptosis role

DOI: 10.1016/j.biopha.2020.110075

PMID: 32179202
Sample: Tissue homogenate
BIOMEDICINE & PHARMACOTHERAPY (2022) IF: 6.53
Diacerein ameliorates letrozole-induced polycystic ovarian syndrome in rats

DOI: 10.1016/j.biopha.2022.112870

PMID: 35367769
Sample: serum
Oxidative Medicine and Cellular Longevity (2022) IF: 6.543
Potential Therapeutic Effects of Mi-Jian-Chang-Pu Decoction on Neurochemical and Metabolic Changes of Cerebral Ischemia-Reperfusion Injury in Rats

DOI: 10.1155/2022/7319563

PMID: 35578728
Sample: brain
Oxidative Medicine and Cellular Longevity (2021) IF: 6.543
Euryops arabicus Promotes Healing of Excised Wounds in Rat Skin: Emphasis on Its Collagen-Enhancing, Antioxidant, and Anti-Inflammatory Activities

DOI: 10.1155/2021/8891445

PMID: 33574987
Sample: Tissue homogenate
Oxidative Medicine and Cellular Longevity (2022) IF: 6.543
Carveol Promotes Nrf2 Contribution in Depressive Disorders through an Anti-inflammatory Mechanism

DOI: 10.1155/2022/4509204

PMID: 35295720
Sample: cortical,hippocampal brain
Frontiers in Nutrition (2022) IF: 6.576
Comparative Analysis of the Bioactive Compounds in Chicken Cartilage: Protective Effects of Chondroitin Sulfate and Type II Collagen Peptides Against Osteoarthritis Involve Gut Microbiota

DOI: 10.3389/fnut.2022.843360

Sample: synovial fluid,serum
Cells (2019) IF: 6.6
Anti-Neuroinflammatory Effect of Alantolactone through the Suppression of the NF-κB and MAPK Signaling Pathways

DOI: 10.3390/cells8070739

Sample: PC12 cells
PHYTOMEDICINE (2022) IF: 6.656
Integration of transdermal chemistry and network pharmacology to decipher the mechanism of ShexiangZhuifeng analgesic plaster to treat rheumatoid arthritis

DOI: 10.1016/j.phymed.2022.154507

PMID: 36334391
Sample: serum
PHYTOMEDICINE (2022) IF: 6.656
A discovery of clinically approved Panlongqi Tablet for repositioning to treat osteoarthritis by inhibiting PI3K/AKT activation

DOI: 10.1016/j.phymed.2022.154360

Sample: serum
Frontiers in Cell and Developmental Biology (2021) IF: 6.684
Emodin Prevented Depression in Chronic Unpredicted Mild Stress-Exposed Rats by Targeting miR-139-5p/5-Lipoxygenase

DOI: 10.3389/fcell.2021.696619

PMID: 34381778
Sample: hippocampal
Nutrients (2022) IF: 6.706
Supplementation of Lycium barbarum Polysaccharide Combined with Aerobic Exercise Ameliorates High-Fat-Induced Nonalcoholic Steatohepatitis via AMPK/PPARα/PGC-1α Pathway

DOI: 10.3390/nu14153247

Sample: serum
Nutrients (2022) IF: 6.706
Cornuside Is a Potential Agent against Alzheimer’s Disease via Orchestration of Reactive Astrocytes

DOI: 10.3390/nu14153179

Sample: C6 cell
Nutrients (2022) IF: 6.706
Ascophyllum nodosum and Fucus vesiculosus Extracts Improved Lipid Metabolism and Inflammation in High-Energy Diet–Induced Hyperlipidemia Rats

DOI: 10.3390/nu14214665

Sample: serum
LIFE SCIENCES (2022) IF: 6.78
Nephroprotective potential of eugenol in a rat experimental model of chronic kidney injury; targeting NOX, TGF-β, and Akt signaling

DOI: 10.1016/j.lfs.2022.120957

PMID: 36113730
Sample: serum
LIFE SCIENCES (2022) IF: 6.78
Combined apocynin and carvedilol protect against cadmium-induced testicular damage via modulation of inflammatory response and redox-sensitive pathways

DOI: 10.1016/j.lfs.2022.121152

Sample: testis
LIFE SCIENCES (2022) IF: 6.78
Apocynin and its chitosan nanoparticles attenuated cisplatin-induced multiorgan failure: Synthesis, characterization, and biological evaluation

DOI: 10.1016/j.lfs.2022.121313

Sample: heart,liver,kidney
BRITISH JOURNAL OF PHARMACOLOGY (2018) IF: 6.81
High‐fructose corn syrup consumption in adolescent rats causes bipolar‐like behavioural phenotype with hyperexcitability in hippocampal CA3‐CA1 synapses

DOI: 10.1111/bph.14500

Sample: Serum
Journal of Inflammation Research (2021) IF: 6.922
Caffeic Acid Phenethyl Ester reduces Pro Inflammatory Cytokines in Moderate Swimming Test in Growing Rats Model

DOI: 10.2147/JIR.S338973

Sample: serum
Journal of Inflammation Research (2021) IF: 6.922
Anti-Inflammatory Potentials of the n-Hexane Fraction of Alstonia boonei Stem Bark in Lipopolysaccharide-Induced Inflammation in Wistar Rats

DOI: 10.2147/JIR.S304076

Sample: serum
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022) IF: 6.953
Metabolites of gut microbiota fermenting Poria cocos polysaccharide alleviates chronic nonbacterial prostatitis in rats

DOI: 10.1016/j.ijbiomac.2022.04.029

PMID: 35398386
Sample: prostate
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021) IF: 6.953
Lycium barbarum polysaccharide combined with aerobic exercise ameliorated nonalcoholic fatty liver disease through restoring gut microbiota, intestinal barrier and inhibiting hepatic inflammation

DOI: 10.1016/j.ijbiomac.2021.05.066

PMID: 33992651
Sample: Tissue homogenate(Liver)
BIOMACROMOLECULES (2021) IF: 6.988
Fabrication of In Situ Layered Hydrogel Scaffold for the Co-delivery of PGDF-BB/Chlorhexidine to Regulate Proinflammatory Cytokines, Growth Factors, and MMP-9 in a Diabetic Skin Defect Albino Rat Model

DOI: 10.1021/acs.biomac.0c01709

PMID: 33899465
Sample: Tissue homogenate,Serum
LIFE SCIENCES (2022) IF: 5.037
Suppression of PCSK9/NF-kB-dependent pathways by acetate ameliorates cardiac inflammation in a rat model of polycystic ovarian syndrome

DOI: 10.1016/j.lfs.2022.120560

PMID: 35452635
Sample: blood,cardiac tissue
LIFE SCIENCES (2022) IF: 5.037
Role of JNK, ERK, and p38 MAPK signaling pathway in protective effect of sildenafil in cyclophosphamide-induced placental injury in rats

DOI: 10.1016/j.lfs.2022.120354

PMID: 35074407
Sample: Placentae
LIFE SCIENCES (2021) IF: 5.037
Regulation of IL-6/STAT-3/Wnt axis by nifuroxazide dampens colon ulcer in acetic acid-induced ulcerative colitis model: Novel mechanistic insight

DOI: 10.1016/j.lfs.2021.119433

PMID: 33794250
Sample: Serum
LIFE SCIENCES (2021) IF: 5.037
Protective effects of hesperidin through attenuation of Ki67 expression against DMBA-induced breast cancer in female rats

DOI: 10.1016/j.lfs.2021.119957

PMID: 34530017
Sample: Breast tissue
LIFE SCIENCES (2021) IF: 5.037
Phosphodiesterase (1, 3 & 5) inhibitors attenuate diclofenac-induced acute kidney toxicity in rats

DOI: 10.1016/j.lfs.2021.119506

PMID: 33865881
Sample: Whole Blood,Tissue homogenate,Tissue Slice
LIFE SCIENCES (2021) IF: 5.037
Nifuroxazide suppresses UUO-induced renal fibrosis in rats via inhibiting STAT-3/NF-κB signaling, oxidative stress and inflammation

DOI: 10.1016/j.lfs.2021.119241

PMID: 33600861
Sample: Tissue homogenate(kidney)
LIFE SCIENCES (2019) IF: 5.037
Myocardial caspase-3 and NF-κB activation promotes calpain-induced septic apoptosis: The role of Akt/eNOS/NO pathway

DOI: 10.1016/j.lfs.2019.02.048

PMID: 30807754
Sample: Serum,Tissue homogenate
LIFE SCIENCES (2021) IF: 5.037
Arjunolic acid downregulates elevated blood sugar and pro-inflammatory cytokines in streptozotocin (STZ)-nicotinamide induced type 2 diabetic rats

DOI: 10.1016/j.lfs.2021.120232

PMID: 34919901
Sample: serum,pancreatic tissue
LIFE SCIENCES (2021) IF: 5.037
Agomelatine prevents gentamicin nephrotoxicity by attenuating oxidative stress and TLR-4 signaling, and upregulating PPARγ and SIRT1

DOI: 10.1016/j.lfs.2021.119600

PMID: 33984362
Sample: Serum
MOLECULAR NEUROBIOLOGY (2018) IF: 5.076
Ovariectomized Rat Model: Role of PI3K/Akt Pathway

DOI: 10.1007/s12035-018-0966-3

Sample: Tissue homogenate
Oxidative Medicine and Cellular Longevity (2020) IF: 5.076
Neuregulin-1β Protects the Rat Diaphragm during Sepsis against Oxidative Stress and Inflammation by Activating the PI3K/Akt Pathway

DOI: 10.1155/2020/1720961

Sample: Serum,Tissue homogenate
Oxidative Medicine and Cellular Longevity (2020) IF: 5.076
Ellagic Acid Protects Dopamine Neurons via Inhibition of NLRP3 Inflammasome Activation in Microglia

DOI: 10.1155/2020/2963540

PMID: 33294118
Sample: Cell culture medium
Frontiers in Immunology (2020) IF: 5.085
Corilagin Ameliorates Atherosclerosis in Peripheral Artery Disease via the Toll-Like Receptor-4 Signaling Pathway in vitro and in vivo

DOI: 10.3389/fimmu.2020.01611

Sample: plasma
Frontiers in Medicine (2022) IF: 5.093
The Role of the Superior Cervical Sympathetic Ganglion in Ischemia Reperfusion-Induced Acute Kidney Injury in Rats

DOI: 10.3389/fmed.2022.792000

PMID: 35530034
Sample: plasma
INFLAMMOPHARMACOLOGY (2022) IF: 5.093
Pterostilbene improves CFA-induced arthritis and peripheral neuropathy through modulation of oxidative stress, inflammatory cytokines and neurotransmitters in Wistar rats

DOI: 10.1007/s10787-022-01069-w

PMID: 36138303
Sample: serum
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2017) IF: 5.104
Bifidobacterium Infantis Ameliorates Chemotherapy-Induced Intestinal Mucositis Via Regulating T Cell Immunity in Colorectal Cancer Rats

DOI: 10.1159/000480005

Sample: Serum
CHEMOSPHERE (2019) IF: 5.108
Impact of binary waterborne mixtures of nickel and zinc on hypothalamic-pituitary-testicular axis in rats

DOI: 10.1016/j.chemosphere.2019.124501

PMID: 31398612
Sample: Serum
MOLECULAR NEUROBIOLOGY (2015) IF: 5.137
Role of Rho Kinase Inhibition in the Protective Effect of Fasudil and Simvastatin Against 3-Nitropropionic Acid-Induced Striatal Neurodegeneration and Mitochondrial Dysfunction in Rats

DOI: 10.1007/s12035-015-9303-2

Sample: the second striatum
Frontiers in Neuroscience (2022) IF: 5.152
Inhibition of BET Protein Function Suppressed the Overactivation of the Canonical NF-κB Signaling Pathway in 6-OHDA-Lesioned Rat Model of Levodopa-Induced Dyskinesia

DOI: 10.3389/fnins.2022.896322

PMID: 35801173
Sample: striatal tissue
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020) IF: 5.162
Colchicine mesoporous silica nanoparticles/hydrogel composite loaded cotton patches as a new encapsulator system for transdermal osteoarthritis management

DOI: 10.1016/j.ijbiomac.2020.07.133

PMID: 32693125
Sample: Serum
CHEMICO-BIOLOGICAL INTERACTIONS (2023) IF: 5.168
p-CREB and p-DARPP-32 orchestrating the modulatory role of cAMP/PKA signaling pathway enhanced by Roflumilast in rotenone-induced Parkinson's disease in rats

DOI: 10.1016/j.cbi.2023.110366

Sample: Striata
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2019) IF: 5.176
Emodin Rescued Hyperhomocysteinemia-Induced Dementia and Alzheimer’s Disease-Like Features in Rats

DOI: 10.1093/ijnp/pyy090

Sample: Plasma,Tissue homogenate
Aging-US (2018) IF: 5.179
Methanolic extract of Tamarix Gallica attenuates hyperhomocysteinemia induced AD-like pathology and cognitive impairments in rats

DOI: 10.18632/aging.101627

PMID: 30425189
Sample: Tissue homogenate
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2022) IF: 5.19
Mechanistic insights on the possible protective role of polyphenols extracted from Tamarix aphylla aerial parts against sodium arsenite-induced hepatotoxicity in rats

DOI: 10.1007/s11356-022-23324-x

PMID: 36190635
Sample: serum
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2023) IF: 5.19
Betulinic acid protects against cardiotoxicity of the organophosphorus pesticide chlorpyrifos by suppressing oxidative stress, inflammation, and apoptosis in rats

DOI: 10.1007/s11356-023-25917-6

Sample: heart
FASEB JOURNAL (2020) IF: 5.192
Pre‐ischemic renal lavage protects against renal ischemia‐reperfusion injury by attenuation of local and systemic inflammatory responses

DOI: 10.1096/fj.201902943R

Sample: Plasma
CHEMICO-BIOLOGICAL INTERACTIONS (2021) IF: 5.194
Targeting inflammation and redox aberrations by perindopril attenuates methotrexate-induced intestinal injury in rats: Role of TLR4/NF-κB and c-Fos/c-Jun pro-inflammatory pathways and PPAR-γ/SIRT1 cytoprotective signals

DOI: 10.1016/j.cbi.2021.109732

PMID: 34737150
Sample: serum
JOURNAL OF ETHNOPHARMACOLOGY (2022) IF: 5.195
Validation of traditional claims of anti-arthritic efficacy of trans-Himalayan snow mountain garlic (Allium ampeloprasum L.) extract using adjuvant-induced arthritis rat model: A comparative evaluation with normal garlic (Allium sativum L.) and dexamethas

DOI: 10.1016/j.jep.2022.115939

PMID: 36435406
Sample: serum
JOURNAL OF ETHNOPHARMACOLOGY (2022) IF: 5.195
Exploring the anti-inflammatory potential of Colocasia esculenta root extract in in-vitro and in-vivo models of inflammation

DOI: 10.1016/j.jep.2022.116021

Sample: serum
JOURNAL OF ETHNOPHARMACOLOGY (2022) IF: 5.195
Evaluation of the in vitro and in vivo anti-inflammatory activity of Gymnosporia montana (Roth). Benth leaves

DOI: 10.1016/j.jep.2022.115539

PMID: 35843412
Sample: RAW 264.7 cell
Pharmaceuticals (2023) IF: 5.215
Sorafenib Alleviates Inflammatory Signaling of Tumor Microenvironment in Precancerous Lung Injuries

DOI: 10.3390/ph16020221

Sample: lung tissue
Pharmaceuticals (2022) IF: 5.215
Lycopene Modulates Oxidative Stress and Inflammation in Hypercholesterolemic Rats

DOI: 10.3390/ph15111420

Sample: Cardiac,Renal
Pharmaceuticals (2022) IF: 5.215
Leukotriene Receptor Antagonist, Montelukast Ameliorates L-NAME-Induced Pre-eclampsia in Rats through Suppressing the IL-6/Jak2/STAT3 Signaling Pathway

DOI: 10.3390/ph15080914

PMID: 35893738
Sample: placental tissue,hepatic tissue,renal tissue
Pharmaceuticals (2022) IF: 5.215
Azithromycin Mitigates Cisplatin-Induced Lung Oxidative Stress, Inflammation and Necroptosis by Upregulating SIRT1, PPARγ, and Nrf2/HO-1 Signaling

DOI: 10.3390/ph16010052
CNS Neuroscience & Therapeutics (2022) IF: 5.243
Transplantation of Roxadustat-preconditioned bone marrow stromal cells improves neurological function recovery through enhancing grafted cell survival in ischemic stroke rats

DOI: 10.1111/cns.13890

PMID: 35695696
Sample: serum
NEUROPHARMACOLOGY (2022) IF: 5.251
Vortioxetine ameliorates motor and cognitive impairments in the rotenone-induced Parkinson's disease via targeting TLR-2 mediated neuroinflammation

DOI: 10.1016/j.neuropharm.2022.108977

PMID: 35092748
Sample: hippocampus,PFC,striatum tissue
BIOORGANIC CHEMISTRY (2021) IF: 5.275
Optimization of pyrazole-based compounds with 1,2,4-triazole-3-thiol moiety as selective COX-2 inhibitors cardioprotective drug candidates: Design, synthesis, cyclooxygenase inhibition, anti-inflammatory, ulcerogenicity, cardiovascular evaluation, and mol

DOI: 10.1016/j.bioorg.2021.105122

Sample: serum
Frontiers in Cellular and Infection Microbiology (2022) IF: 5.293
Intestinal Epithelial Cell Exosome Launches IL-1β-Mediated Neuron Injury in Sepsis-Associated Encephalopathy

DOI: 10.3389/fcimb.2021.783049

PMID: 35111693
Sample: serum,hippocampal tissue
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021) IF: 5.31
Oxidized high-density lipoprotein enhances endocrine disorders and ovarian damage in rats

DOI: 10.1111/jcmm.16197

PMID: 34346538
Sample: granulosa cells (GCs)
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021) IF: 5.31
Normothermic machine perfusion attenuates hepatic ischaemia-reperfusion injury by inhibiting CIRP-mediated oxidative stress and mitochondrial fission

DOI: 10.1111/jcmm.17062

PMID: 34786826
Sample: serum
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2022) IF: 5.31
New insights into the central sympathetic hyperactivity post-myocardial infarction: Roles of METTL3-mediated m6A methylation

DOI: 10.1111/jcmm.17183

Sample: paraventricular nucleus(PVN) tissue
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021) IF: 5.31
Mesenchymal stem cells ameliorate silica-induced pulmonary fibrosis by inhibition of inflammation and epithelial-mesenchymal transition

DOI: 10.1111/jcmm.16621

PMID: 34076355
Sample: lung,bronchoalveolar lavage fluid
PHYTOMEDICINE (2021) IF: 5.34
The piperine derivative HJ105 inhibits Aβ1-42-induced neuroinflammation and oxidative damage via the Keap1-Nrf2-TXNIP axis

DOI: 10.1016/j.phymed.2021.153571

Sample: Tissue homogenate(hippocampus)
PHYTOMEDICINE (2021) IF: 5.34
Extracts of Poria cocos improve functional dyspepsia via regulating brain-gut peptides, immunity and repairing of gastrointestinal mucosa

DOI: 10.1016/j.phymed.2021.153875

PMID: 34911003
Sample: serum
PHYTOMEDICINE (2021) IF: 5.34
Cardioprotective activity of ethyl acetate extract of Cinnamomi Ramulus against myocardial ischemia/reperfusion injury in rats via inhibiting NLRP3 inflammasome activation and pyroptosis

DOI: 10.1016/j.phymed.2021.153798

PMID: 34673348
Sample: serum
JOURNAL OF NEUROCHEMISTRY (2021) IF: 5.372
Zinc induces reactive astrogliosis through ERK dependent activation of Stat3 and promotes synaptic degeneration

DOI: 10.1111/jnc.15531

Sample: primary astrocyte
JOURNAL OF NEUROCHEMISTRY (2021) IF: 5.372
Inhibiting Brd4 alleviated PTSD-like behaviors and fear memory through regulating immediate early genes expression and neuroinflammation in rats

DOI: 10.1111/jnc.15439

PMID: 34050937
Sample: Tissue homogenate
Food & Function (2021) IF: 5.396
Physalin B inhibits PDGF-BB-induced VSMC proliferation, migration and phenotypic transformation by activating the Nrf2 pathway

DOI: 10.1039/D1FO01926K

PMID: 34647944
Sample: VSMC
Chinese Medicine (2022) IF: 5.455
Combination of pseudoephedrine and emodin ameliorates LPS-induced acute lung injury by regulating macrophage M1/M2 polarization through the VIP/cAMP/PKA pathway

DOI: 10.1186/s13020-021-00562-8

PMID: 35123524
Sample: serum
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018) IF: 5.5
Down-Regulation of miR-327 Alleviates Ischemia/Reperfusion-Induced Myocardial Damage by Targeting RP105

DOI: 10.1159/000493288

Sample: myocardial tissues
Journal of the American Heart Association (2022) IF: 5.501
Trimetazidine Alleviates Postresuscitation Myocardial Dysfunction and Improves 96‐Hour Survival in a Ventricular Fibrillation Rat Model

DOI: 10.1161/JAHA.121.023378

Sample: myocardial tissue
JOURNAL OF CELLULAR PHYSIOLOGY (2020) IF: 5.546
Autophagy decreases alveolar epithelial cell injury by regulating the release of inflammatory mediators

DOI: 10.1002/jcp.29453

PMID: 31960959
Sample: Cell culture supernatant,Tissue homogenate
Frontiers in Endocrinology (2021) IF: 5.555
Chondroitin Sulfate Alleviates Diabetic Osteoporosis and Repairs Bone Microstructure via Anti-Oxidation, Anti-Inflammation, and Regulating Bone Metabolism

DOI: 10.3389/fendo.2021.759843

PMID: 34777254
Sample: serum
Nanomedicine-Nanotechnology Biology and Medicine (2019) IF: 5.57
Delivery of siRNA using folate receptor-targeted pH-sensitive polymeric nanoparticles for rheumatoid arthritis therapy

DOI: 10.1016/j.nano.2019.102017

PMID: 31128293
Sample: Plasma
FOOD AND CHEMICAL TOXICOLOGY (2022) IF: 5.572
Banana peel ameliorated hepato-renal damage and exerted anti-inflammatory and anti-apoptotic effects in metal mixture mediated hepatic nephropathy by activation of Nrf2/ Hmox-1 and inhibition of Nfkb pathway

DOI: 10.1016/j.fct.2022.113471

PMID: 36270409
Sample: liver,kidney
Metabolites (2023) IF: 5.581
Neonatal Orally Administered Zingerone Attenuates Alcohol-Induced Fatty Liver Disease in Experimental Rat Models

DOI: 10.3390/metabo13020167

Sample: plasma
FASEB JOURNAL (2018) IF: 5.595
Hypothermic oxygenated perfusion (HOPE) attenuates ischemia/reperfusion injury in the liver through inhibition of the TXNIP/NLRP3 inflammasome pathway in a rat model of donation after cardiac death

DOI: 10.1096/fj.201800028RR

Sample: Tissue homogenate
ARTHRITIS RESEARCH & THERAPY (2022) IF: 5.606
Targeting clock-controlled gene Nrf2 ameliorates inflammation-induced intervertebral disc degeneration

DOI: 10.1186/s13075-022-02876-w

PMID: 35922862
Sample: NP cell
EXPERIMENTAL NEUROLOGY (2022) IF: 5.62
MicroRNA-140-5p shuttled by microglia-derived extracellular vesicles attenuates subarachnoid hemorrhage-induced microglia activation and inflammatory response via MMD downregulation

DOI: 10.1016/j.expneurol.2022.114265

Sample: brain
RESPIRATORY RESEARCH (2021) IF: 5.631
Artesunate ameliorates cigarette smoke-induced airway remodelling via PPAR-γ/TGF-β1/Smad2/3 signalling pathway

DOI: 10.1186/s12931-021-01687-y

PMID: 33757521
Sample: BALF
Frontiers in Molecular Neuroscience (2021) IF: 5.639
Selected Thiadiazine-Thione Derivatives Attenuate Neuroinflammation in Chronic Constriction Injury Induced Neuropathy

DOI: 10.3389/fnmol.2021.728128

PMID: 34975395
Sample: spinal cord tissue
Molecular Therapy-Nucleic Acids (2018) IF: 5.66
miR-93-5p-Containing Exosomes Treatment Attenuates Acute Myocardial Infarction-Induced Myocardial Damage

DOI: 10.1016/j.omtn.2018.01.010

Sample: H9c2 cells
Artificial Cells Nanomedicine and Biotechnology (2022) IF: 5.678
Evaluation of tenofovir disoproxil fumarate loaded silver nanoparticle on testicular morphology in experimental type-2 diabetic rats

DOI: 10.1080/21691401.2022.2042009

PMID: 35343349
Sample: testicular
MOLECULAR NEUROBIOLOGY (2022) IF: 5.682
Activation of Angiotensin-converting Enzyme 2 Protects Against Lipopolysaccharide-induced Glial Activation by Modulating Angiotensin-converting Enzyme 2/Angiotensin (1–7)/Mas Receptor Axis

DOI: 10.1007/s12035-022-03061-5

Sample: cortex,hippocampus,C6 cell
REDOX REPORT (2022) IF: 5.696
Atorvastatin-mediated downregulation of VCAM-1 and XO/UA/caspase 3 signaling averts oxidative damage and apoptosis induced by ovarian ischaemia/reperfusion injury

DOI: 10.1080/13510002.2022.2129192

PMID: 36200598
Sample: ovarian
INTERNATIONAL IMMUNOPHARMACOLOGY (2022) IF: 5.714
Thiadiazine-thione derivatives ameliorate STZ-induced diabetic neuropathy by regulating insulin and neuroinflammatory signaling

DOI: 10.1016/j.intimp.2022.109421

Sample: Spinal cord
ENVIRONMENTAL POLLUTION (2019) IF: 5.714
Selenium abates reproductive dysfunction via attenuation of biometal accumulation, oxido-inflammatory stress and caspase-3 activation in male rats exposed to arsenic

DOI: 10.1016/j.envpol.2019.113079

PMID: 31473390
Sample: Serum
INTERNATIONAL IMMUNOPHARMACOLOGY (2023) IF: 5.714
Escin alleviates stress-induced intestinal dysfunction to protect brain injury by regulating the gut-brain axis in ischemic stroke rats

DOI: 10.1016/j.intimp.2022.109659

Sample: plasma
GENOMICS (2021) IF: 5.736
Up-regulated microRNA-132 reduces the cognition-damaging effect of sevoflurane on Alzheimer's disease rats by inhibiting FOXA1

DOI: 10.1016/j.ygeno.2021.08.011

PMID: 34400241
Sample: hippocampal tissue
Frontiers in Pharmacology (2021) IF: 5.811
β-Patchoulene Ameliorates Water Transport and the Mucus Barrier in 5-Fluorouracil-Induced Intestinal Mucositis Rats via the cAMP/PKA/CREB Signaling Pathway

DOI: 10.3389/fphar.2021.689491

Sample: Intestinal
Frontiers in Pharmacology (2022) IF: 5.811
Ursolic Acid Protects Neurons in Temporal Lobe Epilepsy and Cognitive Impairment by Repressing Inflammation and Oxidation.

DOI: 10.3389/fphar.2022.877898

Sample: hippocampal tissue
Frontiers in Pharmacology (2021) IF: 5.811
Salvianolate Ameliorates Osteopenia and Improves Bone Quality in Prednisone-Treated Rheumatoid Arthritis Rats by Regulating RANKL/RANK/OPG Signaling

DOI: 10.3389/fphar.2021.710169

PMID: 34552485
Sample: serum
Frontiers in Pharmacology (2021) IF: 5.811
Rivaroxaban Modulates TLR4/Myd88/NF-Kβ Signaling Pathway in a Dose-Dependent Manner With Suppression of Oxidative Stress and Inflammation in an Experimental Model of Depression

DOI: 10.3389/fphar.2021.715354

PMID: 34630092
Sample: hippocampal tissue
Frontiers in Pharmacology (2022) IF: 5.811
Naringin Interferes Doxorubicin-Induced Myocardial Injury by Promoting the Expression of ECHS1

DOI: 10.3389/fphar.2022.859755

PMID: 35496302
Sample: H9C2 cell
Frontiers in Pharmacology (2022) IF: 5.811
Elucidation of the Mechanisms and Effective Substances of Paeoniae Radix Rubra Against Toxic Heat and Blood Stasis Syndrome With a Stage-Oriented Strategy.

DOI: 10.3389/fphar.2022.842839

Sample: plasma
Frontiers in Pharmacology (2022) IF: 5.811
Effects of Pereskia aculeate Miller Petroleum Ether Extract on Complete Freund’s Adjuvant-Induced Rheumatoid Arthritis in Rats and its Potential Molecular Mechanisms

DOI: 10.3389/fphar.2022.869810

Sample: serum
Frontiers in Pharmacology (2021) IF: 5.811
Carveol a Naturally-Derived Potent and Emerging Nrf2 Activator Protects Against Acetaminophen-Induced Hepatotoxicity

DOI: 10.3389/fphar.2020.621538

PMID: 33597885
Sample: Tissue homogenate
Translational Stroke Research (2019) IF: 5.847
AAV/BBB-Mediated Gene Transfer of CHIP Attenuates Brain Injury Following Experimental Intracerebral Hemorrhage

DOI: 10.1007/s12975-019-00715-w

PMID: 31325153
Sample: Plasma
Bone & Joint Research (2021) IF: 5.853
PARP-1 inhibition attenuates the inflammatory response in the cartilage of a rat model of osteoarthritis

DOI: 10.1302/2046-3758.107.BJR-2020-0200.R2

PMID: 34254815
Sample: serum
Pharmaceuticals (2022) IF: 5.863
Xanthine Oxidase Inhibitor, Febuxostat Is Effective against 5-Fluorouracil-Induced Parotid Salivary Gland Injury in Rats Via Inhibition of Oxidative Stress, Inflammation and Targeting TRPC1/CHOP Signalling Pathway

DOI: 10.3390/ph15020232

Sample: parotid salivary gland
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021) IF: 5.875
PLGA/PCADK composite microspheres containing hyaluronic acid–chitosan siRNA nanoparticles: A rational design for rheumatoid arthritis therapy

DOI: 10.1016/j.ijpharm.2021.120204

Sample: Serum
Materials Science & Engineering C-Materials for Biological Applications (2020) IF: 5.88
The sustained release of dexamethasone from TiO2 nanotubes reinforced by chitosan to enhance osteoblast function and anti-inflammation activity

DOI: 10.1016/j.msec.2020.111241

Sample: Cell culture supernatant
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022) IF: 5.924
The Effects of a Meldonium Pre-Treatment on the Course of the LPS-Induced Sepsis in Rats

DOI: 10.3390/ijms23042395

PMID: 35216510
Sample: serum
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021) IF: 5.924
Pantoprazole Attenuates MAPK (ERK1/2, JNK, p38)–NF-κB and Apoptosis Signaling Pathways after Renal Ischemia/Reperfusion Injury in Rats

DOI: 10.3390/ijms221910669

Sample: serum
Frontiers in Pharmacology (2022) IF: 5.988
Tormentic Acid Ameliorates Hepatic Fibrosis in vivo by Inhibiting Glycerophospholipids Metabolism and PI3K/Akt/mTOR and NF-κB Pathways: Based on Transcriptomics and Metabolomics.

DOI: 10.3389/fphar.2022.801982

Sample: hepatic tissue
Frontiers in Pharmacology (2022) IF: 5.988
Pharmacological investigation of brucine anti-ulcer potential

DOI: 10.3389/fphar.2022.886433

PMID: 36059979
Sample: stomach tissue
Frontiers in Pharmacology (2022) IF: 5.988
Pharmacological basis of bergapten in gastrointestinal diseases focusing on H+/K+ ATPase and voltage-gated calcium channel inhibition: A toxicological evaluation on vital organs

DOI: 10.3389/fphar.2022.1005154

Sample: stomach tissue
Frontiers in Pharmacology (2022) IF: 5.988
Effect of Rumex dentatus on Gastrointestinal Protection and Toxicology in Rodents via Investigating H⁺/K⁺-ATPase, Calcium Channels, and PDE Mediated Signaling.

DOI: 10.3389/fphar.2022.936161

Sample: Stomach tissue
Frontiers in Pharmacology (2022) IF: 5.988
Anti-arthritic and toxicological evaluation of ethanolic extract of Alternanthera bettzickiana in rats.

DOI: 10.3389/fphar.2022.1002037

Sample: serum
Scientific Reports (2019) IF: 4.011
Behavioral, electrophysiological and neuropathological characteristics of the occurrence of hypertension in pregnant rats

DOI: 10.1038/s41598-019-40969-w

PMID: 30858526
Sample: Serum
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2021) IF: 4.013
Nicotinamide mononucleotide attenuates doxorubicin-induced cardiotoxicity by reducing oxidative stress, inflammation and apoptosis in rats

DOI: 10.1016/j.abb.2021.109050

PMID: 34610336
Sample: plasma, heart
SAUDI JOURNAL OF BIOLOGICAL SCIENCES (2022) IF: 4.052
Evaluation of testicular torsion management in Ogbomoso, South-Western Nigeria and surgical detorsion-augmented treatment with phytochemical fractions of Corchorus olitorius leaf in experimental rats

DOI: 10.1016/j.sjbs.2022.103495

Sample: testicular tissue
International Journal of Biological Sciences (2019) IF: 4.067
Hydrogen sulfide treatment alleviated ventilator-induced lung injury through regulation of autophagy and endoplasmic reticulum stress

DOI: 10.7150/ijbs.38315

PMID: 31853224
Sample: Serum,Bronchoalveolar Lavage Fluid,Tissue homogena
BRAIN RESEARCH BULLETIN (2021) IF: 4.079
Effect of lobeglitazone on motor function in rat model of Parkinson’s disease with diabetes co-morbidity

DOI: 10.1016/j.brainresbull.2021.05.011

Sample: Tissue homogenate
JOURNAL OF CELLULAR PHYSIOLOGY (2017) IF: 4.08
MSCs ameliorates DPN induced cellular pathology via [Ca2+]i homeostasis and scavenging the pro‐inflammatory cytokines

DOI: 10.1002/jcp.26009

Sample: neuronal cell
BIOLOGICAL TRACE ELEMENT RESEARCH (2023) IF: 4.081
Therapeutic Potential of Selenium Nanoparticles on Letrozole-Induced Polycystic Ovarian Syndrome in Female Wistar Rats

DOI: 10.1007/s12011-023-03579-2

Sample: Serum
INFLAMMATION (2018) IF: 4.092
the NF-κB Pathway in Rats

DOI: 10.1007/s10753-018-0791-x

Sample: Plasma
INFLAMMATION (2021) IF: 4.092
MiR-708-3p Alleviates Inflammation and Myocardial Injury After Myocardial Infarction by Suppressing ADAM17 Expression

DOI: 10.1007/s10753-020-01404-9

PMID: 33492555
Sample: Tissue homogenate,Cell culture supernatant
INFLAMMATION (2017) IF: 4.092
MeCP2 Regulates PTCH1 Expression Through DNA Methylation in Rheumatoid Arthritis

DOI: 10.1007/s10753-017-0591-8

Sample: Cell culture supernatant
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2021) IF: 4.098
Spectrochemical and biochemical assay comparison study of the healing effect of the Aloe vera and Hypericum perforatum loaded nanofiber dressings on diabetic wound

DOI: 10.1016/j.saa.2021.119639

PMID: 33743307
Sample: Serum,Whole Blood
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2022) IF: 4.098
Identification of polycystic ovary syndrome from blood serum using hormone levels via Raman spectroscopy and multivariate analysis

DOI: 10.1016/j.saa.2022.121029

PMID: 35217265
Sample: serum
TOXICOLOGY (2020) IF: 4.099
Protocatechuic acid modulates reproductive dysfunction linked to furan exposure in rats

DOI: 10.1016/j.tox.2020.152556

PMID: 32758512
Sample: Serum,Tissue homogenate
MICROSCOPY AND MICROANALYSIS (2023) IF: 4.099
Impact of Gestational Diabetes on the Thymus Gland of Rat’s Offspring and the Possible Ameliorating Effect of Thymoquinone: Biochemical, Histological, and Immunohistochemical Study

DOI: 10.1093/micmic/ozad007

Sample: thymic tissues
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2015) IF: 4.101
Effect of SDF-1/CXCR4 axis on the migration of transplanted bone mesenchymal stem cells mobilized by erythropoietin toward lesion sites following spinal cord injury

DOI: 10.3892/ijmm.2015.2344

Sample: Tissue homogenate
ENVIRONMENTAL TOXICOLOGY (2022) IF: 4.109
hUC-MSCs exosomal miR-451 alleviated acute lung injury by modulating macrophage M2 polarization via regulating MIF-PI3K-AKT signaling pathway

DOI: 10.1002/tox.23639

Sample: serum,NR8383 cell
ENVIRONMENTAL TOXICOLOGY (2022) IF: 4.119
Platelet-rich plasma exhibits anti-inflammatory effect and attenuates cardiomyocyte damage by reducing NF-κB and enhancing VEGF expression in isoproterenol induced cardiotoxicity model

DOI: 10.1002/tox.23456

PMID: 35014750
Sample: cardiac tissue
ENVIRONMENTAL TOXICOLOGY (2022) IF: 4.119
LncRNA MEG3 ameliorates NiO nanoparticles-induced pulmonary inflammatory damage via suppressing the p38 mitogen activated protein kinases pathway

DOI: 10.1002/tox.23464

PMID: 35006638
Sample: bronchoalveolar lavage fluid (BALF)
ENVIRONMENTAL TOXICOLOGY (2022) IF: 4.119
Iron-induced cellular in vitro neurotoxic responses in rat C6 cell line

DOI: 10.1002/tox.23543

PMID: 35446454
Sample: glioma C6 cell
ENVIRONMENTAL TOXICOLOGY (2021) IF: 4.119
Effects of 2,4-dichlorophenoxyacetic acid on the expression of NLRP3 inflammasome and autophagy-related proteins as well as the protective effect of Lycium barbarum polysaccharide in neonatal rats

DOI: 10.1002/tox.23358

PMID: 34464015
Sample: serum
ENVIRONMENTAL TOXICOLOGY (2022) IF: 4.119
2,4-dichlorophenoxyacetic acid induces ROS activation in NLRP3 inflammatory body-induced autophagy disorder in microglia and the protective effect of Lycium barbarum polysaccharide

DOI: 10.1002/tox.23471

PMID: 35099110
Sample: serum
ACS Omega (2023) IF: 4.132
Curcumin-Loaded Bioactive Polymer Composite Film of PVA/Gelatin/Tannic Acid Downregulates the Pro-inflammatory Cytokines to Expedite Healing of Full-Thickness Wounds

DOI: 10.1021/acsomega.2c07018

Sample: serum
ACS Omega (2022) IF: 4.132
Ajuga bracteosa Exerts Antihypertensive Activity in l-NAME-Induced Hypertension Possibly through Modulation of Oxidative Stress, Proinflammatory Cytokines, and the Nitric Oxide/Cyclic Guanosine Monophosphate Pathway

DOI: 10.1021/acsomega.2c03888

PMID: 36157749
Sample: serum
VASCULAR PHARMACOLOGY (2020) IF: 4.152
Ozagrel a thromboxane A2 synthase inhibitor extenuates endothelial dysfunction, oxidative stress and neuroinflammation in rat model of bilateral common carotid artery occlusion induced vascular dementia

DOI: 10.1016/j.vph.2020.106827

PMID: 33346090
Sample: brain lysate supernatant
Frontiers in Psychiatry (2021) IF: 4.157
Post-weaning Social Isolated Flinders Sensitive Line Rats Display Bio-Behavioural Manifestations Resistant to Fluoxetine: A Model of Treatment-Resistant Depression

DOI: 10.3389/fpsyt.2021.688150

PMID: 34867504
Sample: plasma
Drug Design Development and Therapy (2021) IF: 4.162
Maackiain Protects the Kidneys of Type 2 Diabetic Rats via Modulating the Nrf2/HO-1 and TLR4/NF-κB/Caspase-3 Pathways

DOI: 10.2147/DDDT.S326975

PMID: 34703210
Sample: kidney
Nutrition & Metabolism (2021) IF: 4.169
Diet-induced prediabetes: effects of exercise treatment on risk factors for cardiovascular complications

DOI: 10.1186/s12986-021-00573-0

PMID: 33888141
Sample: Tissue homogenate(heart)
Nutrients (2019) IF: 4.171
Dietary Supplements of Shiikuwasha Extract Attenuates Osteoarthritis Progression in Meniscal/ligamentous Injury and Obese Rats

DOI: 10.3390/nu11061312

Sample: plasma
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019) IF: 4.183
Deep-Fried Atractylodis Rhizoma Protects against Spleen Deficiency-Induced Diarrhea through Regulating Intestinal Inflammatory Response and Gut Microbiota

DOI: 10.3390/ijms21010124

Sample: serum
SAUDI JOURNAL OF BIOLOGICAL SCIENCES (2021) IF: 4.219
Neuroprotective efficacy of 4-Hydroxyisoleucine in experimentally induced intracerebral hemorrhage

DOI: 10.1016/j.sjbs.2021.07.010

PMID: 34764759
Sample: brain
TOXICOLOGY AND APPLIED PHARMACOLOGY (2021) IF: 4.219
MicroRNA-30c-5p protects against myocardial ischemia/reperfusion injury via regulation of Bach1/Nrf2

DOI: 10.1016/j.taap.2021.115637

PMID: 34217758
Sample: serum
TOXICOLOGY (2021) IF: 4.221
3-Indolepropionic acid upturned male reproductive function by reducing oxido-inflammatory responses and apoptosis along the hypothalamic-pituitary-gonadal axis of adult rats exposed to chlorpyrifos

DOI: 10.1016/j.tox.2021.152996

PMID: 34678318
Sample: testes,epididymis,hypothalamus
Frontiers in Pharmacology (2020) IF: 4.225
Sodium Tanshinone II Sulfonate A Ameliorates Hypoxia-Induced Pulmonary Hypertension

DOI: 10.3389/fphar.2020.00687

PMID: 32508639
Sample: Tissue homogenate
Frontiers in Pharmacology (2020) IF: 4.225
Licorice Ameliorates Cisplatin-Induced Hepatotoxicity Through Antiapoptosis, Antioxidative Stress, Anti-Inflammation, and Acceleration of Metabolism

DOI: 10.3389/fphar.2020.563750

PMID: 33240085
Sample: Tissue homogenate
Journal of Clinical Medicine (2021) IF: 4.242
Pharmacological Effects of Methotrexate and Infliximab in a Rats Model of Diet-Induced Dyslipidemia and Beta-3 Overexpression on Endothelial Cells

DOI: 10.3390/jcm10143143

PMID: 34300308
Sample: plasma
Scientific Reports (2017) IF: 4.259
Hydrogen sulfide ameliorates chronic renal failure in rats by inhibiting apoptosis and inflammation through ROS/MAPK and NF- κ B signaling pathways

DOI: 10.1038/s41598-017-00557-2

Sample: Tissue homogenate
Scientific Reports (2017) IF: 4.259
Effect of Qianghuo Erhuang Decoction on T Regulatory and T Helper 17 Cells in Treatment of Adjuvant-induced Arthritis in Rats

DOI: 10.1038/s41598-017-17566-w

Sample: Serum
Toxin Reviews (2021) IF: 4.266
Benzo-a-pyrene-induced reproductive toxicity was abated in rats co-treated with taurine

DOI: 10.1080/15569543.2021.1949617

Sample: testicular,epididymal
TOXICOLOGY LETTERS (2022) IF: 4.271
Sodium para-aminosalicylic acid ameliorates brain neuroinflammation and behavioral deficits in juvenile lead-exposed rats by modulating MAPK signaling pathway and alpha-synuclein

DOI: 10.1016/j.toxlet.2022.12.013
International Journal of Nanomedicine (2017) IF: 4.3
Zinc oxide nanoparticle-induced atherosclerotic alterations in vitro and in vivo

DOI: 10.2147/IJN.S134897

Sample: Cell culture supernatant,Serum
International Journal of Nanomedicine (2017) IF: 4.3
Multifunctional folate receptor-targeting and pH-responsive nanocarriers loaded with methotrexate for treatment of rheumatoid arthritis

DOI: 10.2147/IJN.S140992

Sample: Serum
Drug Design Development and Therapy (2022) IF: 4.319
Carvacrol Alleviates Hyperuricemia-Induced Oxidative Stress and Inflammation by Modulating the NLRP3/NF-κB Pathwayt

DOI: 10.2147/DDDT.S343978

PMID: 35496367
Sample: joint tissue
Drug Design Development and Therapy (2022) IF: 4.319
Alpha-Chymotrypsin Protects Against Acute Lung, Kidney, and Liver Injuries and Increases Survival in CLP-Induced Sepsis in Rats Through Inhibition of TLR4/NF-κB Pathway

DOI: 10.2147/DDDT.S370460

Sample: serum
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2019) IF: 4.328
Inflammation-dependent ISG15 upregulation mediates MIA-induced dendrite damages and depression by disrupting NEDD4/Rap2A signaling

DOI: 10.1016/j.bbadis.2019.02.020

PMID: 30826466
Sample: Serum
ENVIRONMENTAL POLLUTION (2018) IF: 4.358
COPD rat model is more susceptible to cold stress and PM2.5 exposure and the underlying mechanism

DOI: 10.1016/j.envpol.2018.05.034

Sample: Tissue homogenate
JOURNAL OF ETHNOPHARMACOLOGY (2021) IF: 4.36
Ziziphus Oxyphylla hydro-methanolic extract ameliorates hypertension in L-NAME induced hypertensive rats through NO/cGMP pathway and suppression of oxidative stress related inflammatory biomarkers.

DOI: 10.1016/j.jep.2021.114825

Sample: Serum
JOURNAL OF ETHNOPHARMACOLOGY (2021) IF: 4.36
Role of Glutamine-Glutamate/GABA cycle and potential target GLUD2 in alleviation of rheumatoid arthritis by Tripterygium hypoglaucum (levl.) Hutch based on metabolomics and molecular pharmacology

DOI: 10.1016/j.jep.2021.114561

PMID: 34454056
Sample: serum
JOURNAL OF ETHNOPHARMACOLOGY (2022) IF: 4.36
Network pharmacology analysis uncovers the effect on apoptotic pathway by Bu-Fei formula for COPD treatment

DOI: 10.1016/j.jep.2022.115022

PMID: 35074456
Sample: bronchoalveolar lavage fluid (BALF)
JOURNAL OF ETHNOPHARMACOLOGY (2022) IF: 4.36
Nephroprotective mechanisms of Ambrette (Abelmoschus moschatus Medik.) leaf extracts in adriamycin mediated acute kidney injury model of Wistar rats

DOI: 10.1016/j.jep.2022.115221

PMID: 35339624
Sample: Kidney
JOURNAL OF ETHNOPHARMACOLOGY (2021) IF: 4.36
Integrated serum pharmacochemistry and network pharmacological analysis used to explore possible anti-rheumatoid arthritis mechanisms of the Shentong-Zhuyu decoction

DOI: 10.1016/j.jep.2021.113988

PMID: 33667569
Sample: Serum
JOURNAL OF ETHNOPHARMACOLOGY (2021) IF: 4.36
Arjunolic acid from Cyclocarya paliurus ameliorates diabetic retinopathy through AMPK/mTOR/HO-1 regulated autophagy pathway

DOI: 10.1016/j.jep.2021.114772

PMID: 34688801
Sample: retinal tissue
JOURNAL OF ETHNOPHARMACOLOGY (2021) IF: 4.36
Anti-proliferation and anti-inflammation effects of corilagin in rheumatoid arthritis by downregulating NF-κB and MAPK signaling pathways

DOI: 10.1016/j.jep.2021.114791

PMID: 34737112
Sample: serum
JOURNAL OF ETHNOPHARMACOLOGY (2021) IF: 4.36
Aloe vera mitigates dextran sulfate sodium-induced rat ulcerative colitis by potentiating colon mucus barrier

DOI: 10.1016/j.jep.2021.114108

PMID: 33839199
Sample: Tissue homogenate
Scientific Reports (2022) IF: 4.38
Protective effect of ethanolic extract of Echinacea purpurea contained nanoparticles on meniscal/ligamentous injury induced osteoarthritis in obese male rats

DOI: 10.1038/s41598-022-09380-w

PMID: 35354886
Sample: plasma
Scientific Reports (2021) IF: 4.38
Mothers’ cafeteria diet induced sex-specific changes in fat content, metabolic profiles, and inflammation outcomes in rat offspring

DOI: 10.1038/s41598-021-97487-x

Sample: serum
Scientific Reports (2022) IF: 4.38
Chondroitin and glucosamine sulphate reduced proinflammatory molecules in the DRG and improved axonal function of injured sciatic nerve of rats

DOI: 10.1038/s41598-022-06554-4

PMID: 35210446
Sample: dorsal root ganglia
Scientific Reports (2021) IF: 4.38
Acetate rescues defective brain-adipose metabolic network in obese Wistar rats by modulation of peroxisome proliferator-activated receptor-γ

DOI: 10.1038/s41598-021-98605-5

PMID: 34556775
Sample: plasma,brain tissue,adipose tissue
MOLECULAR IMMUNOLOGY (2017) IF: 4.407
NLRC5 promotes cell proliferation via regulating the NF-κB signaling pathway in Rheumatoid arthritis

DOI: 10.1016/j.molimm.2017.08.024

Sample: Tissue homogenate,Cell lysate,Serum
MOLECULES (2022) IF: 4.412
Vincamine Modulates the Effect of Pantoprazole in Renal Ischemia/Reperfusion Injury by Attenuating MAPK and Apoptosis Signaling Pathways

DOI: 10.3390/molecules27041383

PMID: 35209172
Sample: serum
REDOX REPORT (2022) IF: 4.412
Suppression of glutathione system and upregulation of caspase 3-dependent apoptosis mediate rohypnol-induced gastric injury

DOI: 10.1080/13510002.2022.2074128

PMID: 35535549
Sample: gastric tissue
MOLECULES (2021) IF: 4.412
Phenolic Compounds from Mori Cortex Ameliorate Sodium Oleate-Induced Epithelial–Mesenchymal Transition and Fibrosis in NRK-52e Cells through CD36

DOI: 10.3390/molecules26206133

Sample: NRK-52e cell
MOLECULES (2022) IF: 4.412
Guggulsterone Mediated JAK/STAT and PPAR-Gamma Modulation Prevents Neurobehavioral and Neurochemical Abnormalities in Propionic Acid-Induced Experimental Model of Autism

DOI: 10.3390/molecules27030889

Sample: brain,blood plasma
MOLECULES (2021) IF: 4.412
Ameliorative Potential of Hydroethanolic Leaf Extract of Parquetina nigrescens on d-Galactose-Induced Testicular Injury

DOI: 10.3390/molecules26113424

PMID: 34198754
Sample: testicular
NEUROCHEMICAL RESEARCH (2022) IF: 4.414
Stellate Ganglion Block Improves Postoperative Cognitive Dysfunction in aged rats by SIRT1-mediated White Matter Lesion Repair

DOI: 10.1007/s11064-022-03800-z

PMID: 36315371
Sample: serum,white matter samples
NEUROCHEMICAL RESEARCH (2022) IF: 4.414
Sodium Para-aminosalicylic Acid Inhibits Lead-Induced Neuroinflammation in Brain Cortex of Rats by Modulating SIRT1/HMGB1/NF-κB Pathway

DOI: 10.1007/s11064-022-03739-1

PMID: 36063295
Sample: primary cortical neurons
ACS Chemical Neuroscience (2021) IF: 4.418
Synthesis and Biological Evaluation of Benzimidazole Derivatives as Potential Neuroprotective Agents in an Ethanol-Induced Rodent Model

DOI: 10.1021/acschemneuro.0c00659

PMID: 33430586
Sample: Tissue homogenate(Brain)
ACS Chemical Neuroscience (2021) IF: 4.418
Bergapten Attenuates Nitroglycerin-Induced Migraine Headaches through Inhibition of Oxidative Stress and Inflammatory Mediators

DOI: 10.1021/acschemneuro.1c00146

PMID: 34455773
Sample: brain tissue
JOURNAL OF PERIODONTAL RESEARCH (2021) IF: 4.419
Periodontitis exacerbates the renal degenerative effects of obesity in rats

DOI: 10.1111/jre.12919

PMID: 34328646
Sample: kidney
EUROPEAN JOURNAL OF PHARMACOLOGY (2021) IF: 4.432
Quercetin reduces inflammation in a rat model of diabetic peripheral neuropathy by regulating the TLR4/MyD88/NF-κB signalling pathway

DOI: 10.1016/j.ejphar.2021.174607

PMID: 34743981
Sample: serum,sciatic nerves
EUROPEAN JOURNAL OF PHARMACOLOGY (2019) IF: 4.432
PSTPIP2 attenuates joint damage and suppresses inflammation in adjuvant-induced arthritis

DOI: 10.1016/j.ejphar.2019.172558

Sample: serum
EUROPEAN JOURNAL OF PHARMACOLOGY (2022) IF: 4.432
Piperazine ferulate protects against cardiac ischemia/reperfusion injury in rat via the suppression of NLRP3 inflammasome activation and pyroptosis

DOI: 10.1016/j.ejphar.2022.174856

PMID: 35219728
Sample: serum
EUROPEAN JOURNAL OF PHARMACOLOGY (2021) IF: 4.432
Glycyrrhizic acid ameliorates myocardial ischemia-reperfusion injury in rats through inhibiting endoplasmic reticulum stress

DOI: 10.1016/j.ejphar.2021.174353

PMID: 34274339
Sample: serum
EUROPEAN JOURNAL OF PHARMACOLOGY (2020) IF: 4.432
Amelioration of testosterone-induced benign prostatic hyperplasia using febuxostat in rats: The role of VEGF/TGFβ and iNOS/COX-2

DOI: 10.1016/j.ejphar.2020.173631

PMID: 33031799
Sample: Serum
NEUROBIOLOGY OF AGING (2018) IF: 4.454
CIP2A-promoted astrogliosis induces AD-like synaptic degeneration and cognitive deficits

DOI: 10.1016/j.neurobiolaging.2018.11.023

PMID: 30594047
Sample: Tissue homogenate,Cell culture medium
INFLAMMOPHARMACOLOGY (2021) IF: 4.473
The impact of Sambucus nigra L. extract on inflammation, oxidative stress and tissue remodeling in a rat model of lipopolysaccharide-induced subacute rhinosinusitis

DOI: 10.1007/s10787-021-00805-y

PMID: 33881685
Sample: Serum
INFLAMMOPHARMACOLOGY (2021) IF: 4.473
Exploring the role of Aquaporins (AQPs) in LPS induced systemic inflammation and the ameliorative effect of Garcinia in male Wistar rat

DOI: 10.1007/s10787-021-00832-9

PMID: 34106384
Sample: serum
INFLAMMOPHARMACOLOGY (2021) IF: 4.473
Comparison of individual and combination treatments with naproxen, prednisolone and hydroxychloroquine to treat Complete Freund’s Adjuvant induced arthritis

DOI: 10.1007/s10787-021-00875-y

Sample: serum
INFLAMMOPHARMACOLOGY (2021) IF: 4.473
Chemical characterization and anti-arthritic appraisal of Monotheca buxifolia methanolic extract in Complete Freund’s Adjuvant-induced arthritis in Wistar rats

DOI: 10.1007/s10787-020-00783-7

Sample: serum
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2018) IF: 4.491
Dual-functional lipid polymeric hybrid pH-responsive nanoparticles decorated with cell penetrating peptide and folate for therapy against rheumatoid arthritis

DOI: 10.1016/j.ejpb.2018.06.020

Sample: Plasma
JOURNAL OF CELLULAR PHYSIOLOGY (2019) IF: 4.522
Long noncoding RNA MEG3 regulates rheumatoid arthritis by targeting NLRC5

DOI: 10.1002/jcp.28126

PMID: 30644097
Sample: Serum
PSYCHOPHARMACOLOGY (2021) IF: 4.53
Selenium abates manganese–induced striatal and hippocampal toxicity via abrogation of neurobehavioral deficits, biometal accumulation, oxidative stress, inflammation, and caspase-3 activation in rats

DOI: 10.1007/s00213-021-06010-7

Sample: striatum,hippocampus
BIOMEDICINE & PHARMACOTHERAPY (2020) IF: 4.545
Vinpocetine ameliorates L-arginine induced acute pancreatitis via Sirt1/Nrf2/TNF pathway and inhibition of oxidative stress, inflammation, and apoptosis

DOI: 10.1016/j.biopha.2020.110976

PMID: 33202281
Sample: Tissue homogenate(Pancreatic tissue)
BIOMEDICINE & PHARMACOTHERAPY (2020) IF: 4.545
Semen Brassicae reduces thoracic aortic remodeling, inflammation, and oxidative damage in spontaneously hypertensive rats

DOI: 10.1016/j.biopha.2020.110400

PMID: 32570115
Sample: Serum
BIOMEDICINE & PHARMACOTHERAPY (2020) IF: 4.545
Huoxuezhitong capsule ameliorates MIA-induced osteoarthritis of rats through suppressing PI3K/ Akt/ NF-κB pathway

DOI: 10.1016/j.biopha.2020.110471

Sample: Serum
BIOMEDICINE & PHARMACOTHERAPY (2020) IF: 4.545
Effects of Atractylodes Oil on Inflammatory Response and Serum Metabolites in Adjuvant Arthritis Rats

DOI: 10.1016/j.biopha.2020.110130

Sample: serum
BIOMEDICINE & PHARMACOTHERAPY (2020) IF: 4.545
Diacerein protects rats with liver ischemia/reperfusion damage: Down-regulation of TLR4/ NFκ-B signaling pathway

DOI: 10.1016/j.biopha.2020.111063

PMID: 33348310
Sample: Tissue homogenate
BIOMEDICINE & PHARMACOTHERAPY (2020) IF: 4.545
Berberine regulates fecal metabolites to ameliorate 5-fluorouracil induced intestinal mucositis through modulating gut microbiota

DOI: 10.1016/j.biopha.2020.109829

PMID: 31958765
Sample: Tissue homogenate
Nutrients (2020) IF: 4.546
Defatted Tenebrio molitor Larva Fermentation Extract Modifies Steatosis, Inflammation and Intestinal Microflora in Chronic Alcohol-Fed Rats

DOI: 10.3390/nu12051426

PMID: 32423176
Sample: Serum
SAUDI PHARMACEUTICAL JOURNAL (2022) IF: 4.562
Thymoquinone-rich black cumin oil attenuates ibotenic acid-induced excitotoxicity through glutamate receptors in Wistar rats

DOI: 10.1016/j.jsps.2022.10.007

Sample: brain tissue
SAUDI PHARMACEUTICAL JOURNAL (2023) IF: 4.562
6-gingerol ameliorates weight gain and insulin resistance in metabolic syndrome rats by regulating adipocytokines

DOI: 10.1016/j.jsps.2023.01.003

Sample: serum,liver,adipose tissue
Frontiers in Physiology (2021) IF: 4.566
Chronic Intermittent Hypobaric Hypoxia Decreases High Blood Pressure by Stabilizing the Vascular Renin-Angiotensin System in Spontaneously Hypertensive Rats

DOI: 10.3389/fphys.2021.639454

Sample: serum
REPRODUCTIVE BIOMEDICINE ONLINE (2023) IF: 4.567
Cannabidiol as a potential novel treatment for endometriosis by its anti-inflammatory, antioxidative and anti-angiogenic effects in an experimental rat model

DOI: 10.1016/j.rbmo.2023.01.018

Sample: Serum,intraperitoneal fluid
TOXICOLOGY (2022) IF: 4.571
Zinc and selenium mitigated heavy metals mixture (Pb, Al, Hg and Mn) mediated hepatic-nephropathy via modulation of oxido-inflammatory status and NF‑kB signaling in female albino rats

DOI: 10.1016/j.tox.2022.153350

PMID: 36220500
Sample: liver,kidney
Frontiers in Genetics (2021) IF: 4.599
Identifying lncRNA- and Transcription Factor-Associated Regulatory Networks in the Cortex of Rats With Deep Hypothermic Circulatory Arrest.

DOI: 10.3389/fgene.2021.746757

Sample: brain
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2020) IF: 4.604
Study of double-targeting nanoparticles loaded with MCL-1 siRNA and dexamethasone for adjuvant-induced arthritis therapy

DOI: 10.1016/j.ejpb.2020.07.009

PMID: 32681961
Sample: Serum
International Journal of Environmental Research and Public Health (2023) IF: 4.614
Quercetin and Its Derivative Counteract Palmitate-Dependent Lipotoxicity by Inhibiting Oxidative Stress and Inflammation in Cardiomyocytes

DOI: 10.3390/ijerph20043492

Sample: H9c2 cardiomyocytes
Journal of Inflammation Research (2022) IF: 4.631
C/EBPβ Promotes LPS-Induced IL-1β Transcription and Secretion in Alveolar Macrophages via NOD2 Signaling

DOI: 10.2147/JIR.S377499

Sample: NR8383 cell
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2016) IF: 4.652
Hyperbaric Oxygen Intervention Modulates Early Brain Injury after Experimental Subarachnoid Hemorrhage in Rats: Possible Involvement of TLR4/NF-κ B-Mediated Signaling Pathway

DOI: 10.1159/000445586

Sample: Tissue homogenate
INFLAMMATION (2022) IF: 4.657
Inhibition of PD-1 Alters the SHP1/2-PI3K/Akt Axis to Decrease M1 Polarization of Alveolar Macrophages in Lung Ischemia–Reperfusion Injury

DOI: 10.1007/s10753-022-01762-6

Sample: lung tissue
INFLAMMATION (2022) IF: 4.657
Hederagenin Suppresses Inflammation and Cartilage Degradation to Ameliorate the Progression of Osteoarthritis: An In vivo and In vitro Study

DOI: 10.1007/s10753-022-01763-5

Sample: knee articular tissue
Plants-Basel (2023) IF: 4.658
The Effect of Extraction Methods on Phytochemicals and Biological Activities of Green Coffee Beans Extracts

DOI: 10.3390/plants12040712

Sample: plantar tissue
Plants-Basel (2022) IF: 4.658
Influences of Different Extraction Techniques and Their Respective Parameters on the Phytochemical Profile and Biological Activities of Xanthium spinosum L. Extracts

DOI: 10.3390/plants12010096

Sample: plantar tissue
Frontiers in Neuroscience (2021) IF: 4.677
Olanzapine-Induced Activation of Hypothalamic Astrocytes and Toll-Like Receptor-4 Signaling via Endoplasmic Reticulum Stress Were Related to Olanzapine-Induced Weight Gain

DOI: 10.3389/fnins.2020.589650

PMID: 33584172
Sample: Plasma
MEDIATORS OF INFLAMMATION (2020) IF: 4.711
Exploring the Mechanism on the Medullary Visceral Zone Inhibiting the Cholinergic Anti-inflammatory Pathway Induced by Sepsis

DOI: 10.1155/2020/1320278

PMID: 33061821
Sample: Serum
Frontiers in Immunology (2019) IF: 4.716
Naringenin Produces Neuroprotection Against LPS-Induced Dopamine Neurotoxicity via the Inhibition of Microglial NLRP3 Inflammasome Activation

DOI: 10.3389/fimmu.2019.00936

Sample: BV-2 cells
Frontiers in Physiology (2023) IF: 4.755
Effects of different simulated submarine escape depths by free ascent in animal models

DOI: 10.3389/fphys.2023.1107782

Sample: Serum
Biomedicines (2022) IF: 4.757
Kinetin Ameliorates Cisplatin-Induced Hepatotoxicity and Lymphotoxicity via Attenuating Oxidative Damage, Cell Apoptosis and Inflammation in Rats

DOI: 10.3390/biomedicines10071620

PMID: 35884925
Sample: lymphocytes
Biomedicines (2022) IF: 4.757
Effect of Celecoxib and Infliximab against Multiple Organ Damage Induced by Sepsis in Rats: A Comparative Study

DOI: 10.3390/biomedicines10071613

PMID: 35884918
Sample: Serum
JOURNAL OF PSYCHIATRIC RESEARCH (2021) IF: 4.791
Fecal microbiota transplantation ameliorates stress-induced depression-like behaviors associated with the inhibition of glial and NLRP3 inflammasome in rat brain

DOI: 10.1016/j.jpsychires.2021.02.057

PMID: 33677218
Sample: cortex,hippocampus
BIOCHEMICAL PHARMACOLOGY (2019) IF: 4.825
Correlation between angiotensin 1–7-mediated Mas receptor expression with motor improvement, activated STAT3/SOCS3 cascade, and suppressed HMGB-1/RAGE/NF-κB signaling in 6-hydroxydopamine hemiparkinsonian rats

DOI: 10.1016/j.bcp.2019.113681

Sample: Tissue homogenate
Oxidative Medicine and Cellular Longevity (2019) IF: 4.868
Mangiferin Attenuates Myocardial Ischemia-Reperfusion Injury via MAPK/Nrf-2/HO-1/NF-κB In Vitro and In Vivo

DOI: 10.1155/2019/7285434

Sample: serum,LV(left ventricular) myocardium,H9c2 cells
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2016) IF: 4.874
Cinnamaldehyde ameliorates LPS-induced cardiac dysfunction via TLR4-NOX4 pathway: The regulation of autophagy and ROS production

DOI: 10.1016/j.yjmcc.2016.10.017

Sample: Serum
NUTRITION (2022) IF: 4.893
Acetate circumvents impaired metabolic switch in skeletal muscle of letrozole-induced PCOS rat model by suppression of PDK4/NLRP3

DOI: 10.1016/j.nut.2022.111914

Sample: skeletal muscle
MOLECULES (2022) IF: 4.927
Restoration of Hepatic and Intestinal Integrity by Phyllanthus amarus Is Dependent on Bax/Caspase 3 Modulation in Intestinal Ischemia-/Reperfusion-Induced Injury

DOI: 10.3390/molecules27165073

PMID: 36014309
Sample: intestinal,hepatic
MOLECULES (2022) IF: 4.927
Pharmacological Basis of Rumex hastatus D. Don in Gastrointestinal Diseases with Focusing Effects on H+/K+-ATPase, Calcium Channels Inhibition and PDE Mediated Signaling: Toxicological Evaluation on Vital Organs

DOI: 10.3390/molecules27185919

PMID: 36144661
Sample: stomach tissue
MOLECULES (2022) IF: 4.927
Novel Isoxazole Derivative Attenuates Ethanol-Induced Gastric Mucosal Injury through Inhibition of H+/K+-ATPase Pump, Oxidative Stress and Inflammatory Pathways

DOI: 10.3390/molecules27165065

PMID: 36014311
Sample: Stomach tissue
MOLECULES (2022) IF: 4.927
Effect of Natural Adenylcyclase/cAMP/CREB Signalling Activator Forskolin against Intra-Striatal 6-OHDA-Lesioned Parkinson’s Rats: Preventing Mitochondrial, Motor and Histopathological Defects

DOI: 10.3390/molecules27227951

Sample: brain
MOLECULES (2022) IF: 4.927
7-Hydroxyflavone Alleviates Myocardial Ischemia/Reperfusion Injury in Rats by Regulating Inflammation

DOI: 10.3390/molecules27175371

PMID: 36080137
Sample: serum
Metabolites (2022) IF: 4.932
Serum Metabolomics Based on GC-MS Reveals the Antipyretic Mechanism of Ellagic Acid in a Rat Model

DOI: 10.3390/metabo12060479

PMID: 35736412
Sample: serum
INTERNATIONAL IMMUNOPHARMACOLOGY (2019) IF: 4.932
MAST3 modulates the inflammatory response and proliferation of fibroblast-like synoviocytes in rheumatoid arthritis

DOI: 10.1016/j.intimp.2019.105900

Sample: FLSs cells
INTERNATIONAL IMMUNOPHARMACOLOGY (2022) IF: 4.932
Gastroprotective effect of an active ingredients group of Lindera reflexa Hemsl. On Ethanol-Induced gastric ulcers in Rats: Involvement of VEGFR2/ERK and TLR-2/Myd88 signaling pathway

DOI: 10.1016/j.intimp.2022.108673

PMID: 35259712
Sample: blood
INTERNATIONAL IMMUNOPHARMACOLOGY (2021) IF: 4.932
Fisetin attenuates periodontitis through FGFR1/TLR4/NLRP3 inflammasome pathway

DOI: 10.1016/j.intimp.2021.107505

PMID: 33725636
Sample: serum,Cell culture supernatant(THP-1 cells)
INTERNATIONAL IMMUNOPHARMACOLOGY (2019) IF: 4.932
Apigenin attenuates acrylonitrile-induced neuro-inflammation in rats: Involved of inactivation of the TLR4/NF-κB signaling pathway

DOI: 10.1016/j.intimp.2019.105697

Sample: brain
INTERNATIONAL IMMUNOPHARMACOLOGY (2021) IF: 4.932
25-Hydroxycholesterol mitigates hepatic ischemia reperfusion injury via mediating mitophagy

DOI: 10.1016/j.intimp.2021.107643

PMID: 33878616
Sample: Serum
Journal of Inflammation Research (2020) IF: 4.953
Pharmacological Inhibition of Galectin-3 Ameliorates Diabetes-Associated Cognitive Impairment, Oxidative Stress and Neuroinflammation in vivo and in vitro

DOI: 10.2147/JIR.S273858

PMID: 32982368
Sample: Cell culture supernatant,Tissue homogenate
FASEB JOURNAL (2020) IF: 4.966
TGR5 receptor activation attenuates diabetic retinopathy through suppression of RhoA/ROCK signaling

DOI: 10.1096/fj.201902496RR

Sample: retinas
Scientific Reports (2022) IF: 4.996
Immunomodulatory activity of extracts from five edible basidiomycetes mushrooms in Wistar albino rats

DOI: 10.1038/s41598-022-16349-2

PMID: 35859110
Sample: serum
PLANTA MEDICA (2022) IF: 3.007
Curative effect and mechanisms of Radix Arnebiae oil on burn wound healing in rats

DOI: 10.1055/a-1997-5566

Sample: burn wound tissue
European Review for Medical and Pharmacological Sciences (2020) IF: 3.024
Ulinastatin reduces myocardial injury induced by doxorubicin in SD rats.

DOI: 10.26355/eurrev_202010_23437

Sample: Serum
European Review for Medical and Pharmacological Sciences (2020) IF: 3.024
The effect of myocardial infarction-associated transcript 2 (Mirt2) and miR-101 on sepsis-induced myocardial injury in rats.

DOI: 10.26355/eurrev_202006_21528

Sample: Serum
European Review for Medical and Pharmacological Sciences (2020) IF: 3.024
Overexpression of HOXA-AS2 inhibits inflammation and apoptosis in podocytes via sponging miRNA-302b-3p to upregulate TIMP3

DOI: 10.26355/eurrev_202005_21187

Sample: Serum
TOXICON (2022) IF: 3.033
Caffeic acid protects against DNA damage, oxidative and inflammatory mediated toxicities, and upregulated caspases activation in the hepatorenal system of rats treated with aflatoxin B1

DOI: 10.1016/j.toxicon.2021.12.021

PMID: 34995555
Sample: liver,kidney
NEUROSCIENCE LETTERS (2020) IF: 3.046
The novel estrogen receptor GPER1 decreases epilepsy severity and susceptivity in the hippocampus after status epilepticus

DOI: 10.1016/j.neulet.2020.134978

Sample: Hippocampus
SHOCK (2016) IF: 3.048
EFFECT OF INTRAPERITONEAL RESUSCITATION WITH DIFFERENT CONCENTRATIONS OF SODIUM PYRUVATE ON INTESTINAL ISCHEMIA REPERFUSION INJURY IN HEMORRHAGIC SHOCK RAT

DOI: 10.1097/SHK.0000000000000515

Sample: intestinal tissue
JOURNAL OF CHEMICAL NEUROANATOMY (2021) IF: 3.052
Caffeine abrogates oxidative stress imbalance: Its implication on lateral geniculate nucleus and visual cortex following hyaluronic acid exposure

DOI: 10.1016/j.jchemneu.2021.101996

PMID: 34214592
Sample: eye
JOURNAL OF ETHNOPHARMACOLOGY (2016) IF: 3.055
Venenum Bufonis induces rat neuroinflammation by activiating NF-κB pathway and attenuation of BDNF

DOI: 10.1016/j.jep.2016.03.049

Sample: Tissue homogenate
JOURNAL OF ETHNOPHARMACOLOGY (2016) IF: 3.055
Tongxinluo reduces brain edema and inhibits post-ischemic inflammation after middle cerebral artery occlusion in rats

DOI: 10.1016/j.jep.2016.01.026

Sample: Tissue homogenate
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2020) IF: 3.056
Umbelliferone attenuates gentamicin-induced renal toxicity by suppression of TLR-4/NF-κB-p65/NLRP-3 and JAK1/STAT-3 signaling pathways

DOI: 10.1007/s11356-020-11416-5

PMID: 33128149
Sample: Serum
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2020) IF: 3.056
Platelet-rich plasma and/or sildenafil topical applications accelerate and better repair wound healing in rats through regulation of proinflammatory cytokines and collagen/TGF-β1 pathway

DOI: 10.1007/s11356-020-10042-5

PMID: 32671702
Sample: Serum
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2020) IF: 3.056
Kolaviron suppresses dysfunctional reproductive axis associated with multi-walled carbon nanotubes exposure in male rats

DOI: 10.1007/s11356-020-10324-y

PMID: 32812151
Sample: Serum,Tissue homogenate
MOLECULES (2019) IF: 3.06
Plant-Derived Oleanolic Acid (OA) Ameliorates Risk Factors of Cardiovascular Diseases in a Diet-Induced Pre-Diabetic Rat Model: Effects on Selected Cardiovascular Risk Factors

DOI: 10.3390/molecules24020340

PMID: 30669379
Sample: Plasma,Tissue homogenate
Reproductive Sciences (2021) IF: 3.06
Impact of Melatonin on Full-Term Fetal Brain Development and Transforming Growth Factor-β Level in a Rat Model of Preeclampsia

DOI: 10.1007/s43032-021-00497-3

PMID: 33591564
Sample: Tissue homogenate( placental)
MOLECULES (2019) IF: 3.06
Hyaluronic Acid Coated Acid-Sensitive Nanoparticles for Targeted Therapy of Adjuvant-Induced Arthritis in Rats

DOI: 10.3390/molecules24010146

PMID: 30609724
Sample: Serum
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2019) IF: 3.061
Neurobehavioural and biochemical responses associated with exposure to binary waterborne mixtures of zinc and nickel in rats

DOI: 10.1016/j.etap.2019.103294

Sample: cerebellum,cerebrum,liver
PeerJ (2022) IF: 3.061
Effects of combination of obesity, diabetes, and hypoxia on inflammatory regulating genes and cytokines in rat pancreatic tissues and serum

DOI: 10.7717/peerj.13990

PMID: 36213511
Sample: serum
Food Bioscience (2020) IF: 3.067
Curcumin combined with Baicalin attenuated ethanol-induced hepatitis by suppressing p38 MAPK and TSC1/ eIF-2α/ATF4 pathways in rats

DOI: 10.1016/j.fbio.2020.100851

Sample: liver tissue lysate
PROSTAGLANDINS & OTHER LIPID MEDIATORS (2021) IF: 3.072
Anti-inflammatory activity of 2-((3-(chloromethyl)benzoyl)oxy)benzoic acid in LPS-induced rat model

DOI: 10.1016/j.prostaglandins.2021.106549

PMID: 33831580
Sample: Plasma
AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2019) IF: 3.091
Nisin reduces uterine inflammation in rats by modulating concentrations of pro‐ and anti‐inflammatory cytokines

DOI: 10.1111/aji.13096

Sample: Serum
PHYTOTHERAPY RESEARCH (2017) IF: 3.092
Scopoletin‐standardized Morinda elliptica leaf extract suppressed inflammation and cartilage degradation to alleviate osteoarthritis: A preclinical study

DOI: 10.1002/ptr.5949

Sample: Serum
RSC Advances (2017) IF: 3.108
Holistic and dynamic metabolic alterations of traditional Chinese medicine syndrome in a toxic heat and blood stasis syndrome rat model

DOI: 10.1039/C7RA11748E

Sample: plasma
ENVIRONMENTAL TOXICOLOGY (2020) IF: 3.118
Kolaviron ameliorates hepatic and renal dysfunction associated with multiwalled carbon nanotubes in rats

DOI: 10.1002/tox.23011

PMID: 32856799
Sample: Serum
PSYCHOPHARMACOLOGY (2020) IF: 3.13
Kolaviron via anti-inflammatory and redox regulatory mechanisms abates multi-walled carbon nanotubes-induced neurobehavioral deficits in rats

DOI: 10.1007/s00213-019-05432-8

PMID: 31897575
Sample: Tissue homogenate
REPRODUCTIVE TOXICOLOGY (2022) IF: 3.143
Toxicity from a single injection of human umbilical cord mesenchymal stem cells into rat ovaries

DOI: 10.1016/j.reprotox.2022.03.006

PMID: 35307492
Sample: serum
REPRODUCTIVE TOXICOLOGY (2021) IF: 3.143
Repression of HDAC5 by acetate restores hypothalamic-pituitary-ovarian function in type 2 diabetes mellitus

DOI: 10.1016/j.reprotox.2021.10.008

PMID: 34656705
Sample: plasma,hypothalamic,pituitary,ovarian
REPRODUCTIVE TOXICOLOGY (2022) IF: 3.143
Codeine alters female reproductive function by targeting ovarian steroidogenesis and folliculogenesis via the induction of oxidative stress, inflammation, and apoptosis

DOI: 10.1016/j.reprotox.2022.02.001

PMID: 35158039
Sample: serum
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2022) IF: 3.148
Neuroprotection by Trans-Resveratrol in Rats With Intracerebral Hemorrhage: Insights into the Role of Adenosine A1 Receptors

DOI: 10.1093/jnen/nlac047

PMID: 35799401
Sample: brain
IMMUNOBIOLOGY (2023) IF: 3.152
STING mediates SU5416/hypoxia-induced pulmonary arterial hypertension in rats by regulating macrophage NLRP3 inflammasome activation

DOI: 10.1016/j.imbio.2023.152345

Sample: lung tissues,Bone marrow-derived macrophage (BMDMs
Mycotoxin Research (2020) IF: 3.164
Acute aflatoxin B 1 -induced gastro-duodenal and hepatic oxidative damage is preceded by time-dependent hyperlactatemia in rats

DOI: 10.1007/s12550-020-00408-6

Sample: Tissue homogenate,Serum
EUROPEAN JOURNAL OF PHARMACOLOGY (2019) IF: 3.17
Therapeutic effect of treatment with metformin and/or 4-hydroxychalcone in male Wistar rats with nonalcoholic fatty liver disease

DOI: 10.1016/j.ejphar.2019.172699

Sample: serum
EUROPEAN JOURNAL OF PHARMACOLOGY (2019) IF: 3.17
Associations of inflammatory markers and vascular cell adhesion molecule-1 with endothelial dysfunction in collagen-induced arthritis

DOI: 10.1016/j.ejphar.2019.172786

PMID: 31712060
Sample: Serum
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2017) IF: 3.176
Small Molecule Inhibiting Nuclear Factor‐kB Ameliorates Oxidative Stress and Suppresses Renal Inflammation in Early Stage of Alloxan‐Induced Diabetic Nephropathy in Rat

DOI: 10.1111/bcpt.12718

Sample: Tissue homogenate
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2023) IF: 3.195
Pharmacological evaluation of carvacrol anti-migraine potential

DOI: 10.1007/s00210-023-02412-w

Sample: brain
Frontiers in Physiology (2019) IF: 3.201
Protective Effect of Ursolic Acid on the Intestinal Mucosal Barrier in a Rat Model of Liver Fibrosis

DOI: 10.3389/fphys.2019.00956

Sample: liver,ileum
Drug Design Development and Therapy (2020) IF: 3.216
KGF Is Delivered to Inflammatory and Induces the Epithelial Hyperplasia in Trinitrobenzene Sulfonic Acid-Induced Ulcerative Colitis Rats

DOI: 10.2147/DDDT.S227651

Sample: intestinal tissue
NEUROSCIENCE (2016) IF: 3.231
Imipramine and amitriptyline ameliorate the rotenone model of Parkinson’s disease in rats

DOI: 10.1016/j.neuroscience.2016.06.040

Sample: Tissue homogenate
PLoS One (2015) IF: 3.234
Transplantation of Induced Pluripotent Stem Cells Alleviates Cerebral Inflammation and Neural Damage in Hemorrhagic Stroke

DOI: 10.1371/journal.pone.0129881

Sample: Tissue homogenate
PLoS One (2015) IF: 3.234
Osteoprotective Effect of Echinocystic Acid, a Triterpone Component from Eclipta prostrata, in Ovariectomy-Induced Osteoporotic Rats

DOI: 10.1371/journal.pone.0136572

Sample: Serum
MOLECULAR IMMUNOLOGY (2017) IF: 3.236
The protective effect of dexmedetomidine on LPS-induced acute lung injury through the HMGB1-mediated TLR4/NF-κB and PI3K/Akt/mTOR pathways

DOI: 10.1016/j.molimm.2017.12.008

Sample: Bronchoalveolar Lavage Fluid,Serum,Tissue homogena
INFLAMMOPHARMACOLOGY (2020) IF: 3.238
Polystichum braunii extracts inhibit Complete Freund’s adjuvant-induced arthritis via upregulation of I-κB, IL-4, and IL-10, downregulation of COX-2, PGE2, IL-1β, IL-6, NF-κB, and TNF-α, and subsiding oxidative stress

DOI: 10.1007/s10787-020-00688-5

Sample: serum
INFLAMMOPHARMACOLOGY (2020) IF: 3.238
Methanolic extract of Ephedra ciliata promotes wound healing and arrests inflammatory cascade in vivo through downregulation of TNF-α

DOI: 10.1007/s10787-020-00713-7

Sample: serum
INFLAMMOPHARMACOLOGY (2020) IF: 3.238
Investigation of in vivo anti-inflammatory and anti-angiogenic attributes of coumarin-rich ethanolic extract of Melilotus indicus

DOI: 10.1007/s10787-020-00703-9

Sample: serum
PLoS One (2022) IF: 3.24
The effect of TNF-α inhibitor treatment on microRNAs and endothelial function in collagen induced arthritis

DOI: 10.1371/journal.pone.0264558

PMID: 35213638
Sample: serum
PHYSIOLOGY & BEHAVIOR (2021) IF: 3.244
Thromboxane A2 synthase inhibition ameliorates endothelial dysfunction, memory deficits, oxidative stress and neuroinflammation in rat model of streptozotocin diabetes induced dementia

DOI: 10.1016/j.physbeh.2021.113592

PMID: 34534530
Sample: brain
Biomed Research International (2022) IF: 3.246
Lagerstroemia speciosa Ameliorated Blood Pressure in LNAME Induced Hypertension in Experimental Rats through NO/cGMP and Oxidative Stress Modulation

DOI: 10.1155/2022/5894416

Sample: heart tissue
HUMAN & EXPERIMENTAL TOXICOLOGY (2023) IF: 3.247
The IL-6/HO-1/STAT3 signaling pathway is implicated in the amelioration of acetaminophen-induced hepatic toxicity: A neonatal rat model

DOI: 10.1177/09603271231151376

Sample: hepatic
Life-Basel (2023) IF: 3.251
Ferulic Acid Treats Gastric Ulcer via Suppressing Oxidative Stress and Inflammation

DOI: 10.3390/life13020388

Sample: gastric tissue
JOURNAL OF GENE MEDICINE (2020) IF: 3.258
Celastrol mitigates high glucose‐induced inflammation and apoptosis in rat H9c2 cardiomyocytes via miR‐345‐5p/growth arrest‐specific 6

DOI: 10.1002/jgm.3201

Sample: H9c2 cell
NEUROTOXICOLOGY (2019) IF: 3.263
Neuroprotective mechanisms of selenium against arsenic-induced behavioral impairments in rats

DOI: 10.1016/j.neuro.2019.10.009

PMID: 31678059
Sample: Tissue homogenate
NEUROTOXICOLOGY (2019) IF: 3.263
Neuroprotection by luteolin and gallic acid against cobalt chloride-induced behavioural, morphological and neurochemical alterations in Wistar rats

DOI: 10.1016/j.neuro.2019.07.005

Sample: serum
BMC Endocrine Disorders (2022) IF: 3.263
Low-dose spironolactone ameliorates adipose tissue inflammation and apoptosis in letrozole-induced PCOS rat model

DOI: 10.1186/s12902-022-01143-y

PMID: 36071485
Sample: adipose tissue
EUROPEAN JOURNAL OF PHARMACOLOGY (2020) IF: 3.263
Gastrodin alleviates perioperative neurocognitive dysfunction of aged mice by suppressing neuroinflammation

DOI: 10.1016/j.ejphar.2020.173734

PMID: 33220272
Sample: Tissue homogenate(Hippocampal tissues)
NEUROTOXICOLOGY (2019) IF: 3.263
Combined neurotoxic effects of cannabis and nandrolone decanoate in adolescent male rats

DOI: 10.1016/j.neuro.2019.11.001

Sample: hippocampal,prefrontal cortex
MOLECULES (2020) IF: 3.267
Protective Effects of Methoxsalen Supplementation on Chronic Alcohol-induced Osteopenia and Steatosis in Rats

DOI: 10.3390/molecules25051177

Sample: serum
MOLECULES (2020) IF: 3.267
Design, Synthesis, Molecular Docking, Antiapoptotic and Caspase-3 Inhibition of New 1,2,3-Triazole/Bis-2(1H)-Quinolinone Hybrids

DOI: 10.3390/molecules25215057

Sample: Serum
Bioengineered (2021) IF: 3.269
DNA methyltransferase 3 beta mediates the methylation of the microRNA-34a promoter and enhances chondrocyte viability in osteoarthritis

DOI: 10.1080/21655979.2021.2005308

PMID: 34783292
Sample: synovial fluid
Bioengineered (2021) IF: 3.269
Dehydroevodiamine Suppresses Inflammatory Responses in Adjuvant-Induced Arthritis Rats and Human Fibroblast-Like Synoviocytes

DOI: 10.1080/21655979.2021.1999554

PMID: 34719315
Sample: serum
IMMUNOLOGY LETTERS (2020) IF: 3.276
Protective effect of Ganoderic acid A on adjuvant-induced arthritis

DOI: 10.1016/j.imlet.2020.06.010

PMID: 32565114
Sample: Serum
BMC NEUROSCIENCE (2021) IF: 3.288
Metformin attenuates sepsis-induced neuronal injury and cognitive impairment

DOI: 10.1186/s12868-021-00683-8

PMID: 34911449
Sample: hippocampus tissue
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2020) IF: 3.292
Octreotide alleviates pancreatic damage caused by paraquat in rats by reducing inflammatory responses and oxidative stress

DOI: 10.1016/j.etap.2020.103456

PMID: 32673753
Sample: Serum,Tissue homogenate
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2020) IF: 3.292
Chronic exposure of bisphenol A impairs carbohydrate and lipid metabolism by altering corresponding enzymatic and metabolic pathways

DOI: 10.1016/j.etap.2020.103387

PMID: 32339907
Sample: Serum
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2018) IF: 3.293
Inhibition of endoplasmic reticulum stress by 4-phenylbutyric acid prevents vital organ injury in rat acute pancreatitis

DOI: 10.1152/ajpgi.00102.2018

PMID: 30138574
Sample: Serum
INFLAMMOPHARMACOLOGY (2018) IF: 3.304
SB203580 attenuates acute lung injury and inflammation in rats with acute pancreatitis in pregnancy

DOI: 10.1007/s10787-018-0522-9

PMID: 30094758
Sample: Tissue homogenate
INFLAMMOPHARMACOLOGY (2018) IF: 3.304
) protected against osteoarthritis by mitigating inflammation and cartilage degradation: a preclinical study

DOI: 10.1007/s10787-017-0432-2

Sample: serum
Diabetes Metabolic Syndrome and Obesity-Targets and Therapy (2019) IF: 3.319
Cardioprotective effects of a ruthenium (II) Schiff base complex in diet-induced prediabetic rats

DOI: 10.2147/DMSO.S183811

Sample: Tissue homogenate,Plasma
BEHAVIOURAL BRAIN RESEARCH (2021) IF: 3.332
Modulation of nociception and pain-evoked neurobehavioral responses by levetiracetam in a craniotomy pain model

DOI: 10.1016/j.bbr.2021.113728

PMID: 34952028
Sample: serum
Separations (2023) IF: 3.344
Wound Healing Activity of the Flavonoid-Enriched Fraction of Selaginella bryopteris Linn. against Streptozocin-Induced Diabetes in Rats

DOI: 10.3390/separations10030166

Sample: skin
TOXICOLOGY AND APPLIED PHARMACOLOGY (2020) IF: 3.347
Low dose spironolactone-mediated androgen-adiponectin modulation alleviates endocrine-metabolic disturbances in letrozole-induced PCOS

DOI: 10.1016/j.taap.2020.115381

PMID: 33359182
Sample: Plasma
TOXICOLOGY AND APPLIED PHARMACOLOGY (2020) IF: 3.347
Co-administration of Luteolin mitigated toxicity in rats' lungs associated with doxorubicin treatment

DOI: 10.1016/j.taap.2020.115380

PMID: 33358696
Sample: Tissue homogenate
International Journal of Chronic Obstructive Pulmonary Disease (2022) IF: 3.355
The Bufei Jianpi Formula Improves Mucosal Immune Function by Remodeling Gut Microbiota Through the SCFAs/GPR43/NLRP3 Pathway in Chronic Obstructive Pulmonary Disease Rats

DOI: 10.2147/COPD.S359428

PMID: 35673595
Sample: lung tissue
DRUG AND CHEMICAL TOXICOLOGY (2021) IF: 3.356
Rupatadine protects the intestinal mucosa from injury by 5-flurouracil via modulation of inflammation, apoptosis and intestinal permeability

DOI: 10.1080/01480545.2021.1997541

PMID: 34747284
Sample: intestinal
INTERNATIONAL IMMUNOPHARMACOLOGY (2019) IF: 3.361
The ameliorating effect of cannabinoid type 2 receptor activation on brain, lung, liver and heart damage in cecal ligation and puncture-induced sepsis model in rats

DOI: 10.1016/j.intimp.2019.105978

PMID: 31767546
Sample: Tissue homogenate
RSC Advances (2021) IF: 3.361
Folate receptor-targeting mesoporous silica-coated gold nanorod nanoparticles for the synergistic photothermal therapy and chemotherapy of rheumatoid arthritis

DOI: 10.1039/D0RA08689D

Sample: Serum
BIOCHIMIE (2019) IF: 3.362
TLR2 and TLR4 mediate an activation of adipose tissue renin-angiotensin system induced by uric acid

DOI: 10.1016/j.biochi.2019.04.013

Sample: serum,adipocytes
Frontiers in Physiology (2020) IF: 3.367
Effect of Clostridium butyricum and Butyrate on Intestinal Barrier Functions: Study of a Rat Model of Severe Acute Pancreatitis With Intra-Abdominal Hypertension

DOI: 10.3389/fphys.2020.561061

PMID: 33192557
Sample: Plasma
JOURNAL OF BIOCHEMISTRY (2021) IF: 3.387
Lidocaine activates autophagy of astrocytes and ameliorates chronic constriction injury-induced neuropathic pain

DOI: 10.1093/jb/mvaa136

Sample: astrocyte
Biomed Research International (2021) IF: 3.411
Haematococcus pluvialis Carotenoids Enrich Fractions Ameliorate Liver Fibrosis Induced by Thioacetamide in Rats: Modulation of Metalloproteinase and Its Inhibitor

DOI: 10.1155/2021/6631415

PMID: 33628797
Sample: Tissue homogenate( liver)
Biomed Research International (2021) IF: 3.411
Celastrol Attenuates Learning and Memory Deficits in an Alzheimer’s Disease Rat Model

DOI: 10.1155/2021/5574207

Sample: brain
JOURNAL OF ETHNOPHARMACOLOGY (2019) IF: 3.414
Antidiabetic property of miracle fruit plant (Synsepalum dulcificum Shumach. & Thonn. Daniell) leaf extracts in fructose-fed streptozotocin-injected rats via anti-inflammatory activity and inhibition of carbohydrate metabolizing enzymes

DOI: 10.1016/j.jep.2019.112124

Sample: serum
CONNECTIVE TISSUE RESEARCH (2021) IF: 3.417
Evaluation of cytokines in protective effect of docosahexaenoic acid in experimental achilles tendinopathy rat model induced with type-1 collagenase

DOI: 10.1080/03008207.2021.1982915

PMID: 34612118
Sample: serum
Molecular Medicine Reports (2022) IF: 3.423
Adipose‑derived mesenchymal stem cell‑derived HCAR1 regulates immune response in the attenuation of sepsis

DOI: 10.3892/mmr.2022.12795

PMID: 35856408
Sample: blood
DISEASE MARKERS (2021) IF: 3.434
The Roles of Liver Inflammation and the Insulin Signaling Pathway in PM2.5 Instillation-Induced Insulin Resistance in Wistar Rats

DOI: 10.1155/2021/2821673

PMID: 34745386
Sample: serum
JOURNAL OF CELLULAR BIOCHEMISTRY (2019) IF: 3.448
Tao‐Hong‐Si‐Wu decoction reduces ischemia reperfusion rat myoblast cells calcium overloading and inflammation through the Wnt/IP3R/CAMKII pathway

DOI: 10.1002/jcb.28582

Sample: Cell culture supernate
LIFE SCIENCES (2019) IF: 3.448
Preventive effects of fraxin on ischemia/reperfusion-induced acute kidney injury in rats

DOI: 10.1016/j.lfs.2019.117217

Sample: kidney
LIFE SCIENCES (2019) IF: 3.448
Inhibition of JAK-STAT and NF-κB signalling systems could be a novel therapeutic target against insulin resistance and type 2 diabetes

DOI: 10.1016/j.lfs.2019.117045

PMID: 31730866
Sample: Serum
JOURNAL OF CELLULAR BIOCHEMISTRY (2019) IF: 3.448
Evodiamine alleviates kidney ischemia reperfusion injury in rats: A biochemical and histopathological study

DOI: 10.1002/jcb.28976

PMID: 31099131
Sample: Tissue homogenate
SHOCK (2021) IF: 3.454
Comparison of the Protective Effect of Different Mild Therapeutic Hypothermia Temperatures on Intestinal Injury After Cardiopulmonary Resuscitation in Rats

DOI: 10.1097/SHK.0000000000001745

PMID: 33555844
Sample: plasma,intestinal tissue
BIOMEDICINE & PHARMACOTHERAPY (2018) IF: 3.457
Down-regulation of microRNA-21 reduces inflammation and podocyte apoptosis in diabetic nephropathy by relieving the repression of TIMP3 expression

DOI: 10.1016/j.biopha.2018.09.007

Sample: serum
PHARMACEUTICAL BIOLOGY (2021) IF: 3.503
Gynura procumbens ethanol extract improves vascular dysfunction by suppressing inflammation in postmenopausal rats fed a high-fat diet

DOI: 10.1080/13880209.2021.1970199

PMID: 34493166
Sample: plasma
PHARMACEUTICAL BIOLOGY (2021) IF: 3.503
Guizhi-Shaoyao-Zhimu decoction attenuates bone erosion in rats that have collagen-induced arthritis via modulating NF‐κB signalling to suppress osteoclastogenesis

DOI: 10.1080/13880209.2021.1876100

Sample: serum
PHARMACEUTICAL BIOLOGY (2022) IF: 3.503
Combination of puerarin and tanshinone IIA alleviates ischaemic stroke injury in rats via activating the Nrf2/ARE signalling pathway

DOI: 10.1080/13880209.2022.2070221

PMID: 35635784
Sample: serum
European Review for Medical and Pharmacological Sciences (2018) IF: 3.507
Renal ischemia-reperfusion injury attenuated by splenic ischemic preconditioning.

DOI: 10.26355/eurrev_201804_14747

Sample: serum
European Review for Medical and Pharmacological Sciences (2019) IF: 3.507
Influence of lncRNA HOTAIR on acute kidney injury in sepsis rats through regulating miR-34a/Bcl-2 pathway.

DOI: 10.26355/eurrev_201904_17717

Sample: kidney tissues
ORAL DISEASES (2021) IF: 3.511
Pilocarpine improves submandibular gland dysfunction in irradiated rats by downregulating the tight junction protein claudin-4

DOI: 10.1111/odi.13870

Sample: glands
Oxidative Medicine and Cellular Longevity (2015) IF: 3.516
Polydatin Alleviates Small Intestine Injury during Hemorrhagic Shock as a SIRT1 Activator

DOI: 10.1155/2015/965961

Sample: Serum
Toxicology Research (2021) IF: 3.524
Chlorogenic acid abates oxido-inflammatory and apoptotic responses in the liver and kidney of Tamoxifen-treated rats

DOI: 10.1093/toxres/tfab002

Sample: hepatic,renal
JOURNAL OF PHARMACEUTICAL SCIENCES (2021) IF: 3.534
Fabrication of All-Trans Retinoic Acid loaded Chitosan/Tripolyphosphate Lipid Hybrid Nanoparticles as a Novel Oral Delivery Approach for Management of Diabetic Nephropathy in Rats

DOI: 10.1016/j.xphs.2021.05.007

PMID: 34015278
Sample: Serum
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2022) IF: 3.568
Exposure of aluminium to C6 glioma cells modulates molecular and functional neurotoxic markers

DOI: 10.1002/jbt.23210

PMID: 36056780
Sample: C6 cell
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2023) IF: 3.568
Exploring the cardioprotective effects of canagliflozin against cisplatin-induced cardiotoxicity: Role of iNOS/NF-κB, Nrf2, and Bax/cytochrome C/Bcl-2 signals

DOI: 10.1002/jbt.23309

Sample: Cardiac
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2022) IF: 3.568
Examination of antimicrobial effect of fluoxetine in experimental sepsis model: An in vivo study

DOI: 10.1002/jbt.23240

Sample: blood
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2022) IF: 3.575
Sulforaphane protects myocardium from ischemia-reperfusion injury by regulating CaMKIIN2 and CaMKIIδ

DOI: 10.1016/j.bbrc.2022.03.015

PMID: 35316762
Sample: sera
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2021) IF: 3.575
Effects of hydroxysafflor yellow A on rats with collagen-induced arthritis

DOI: 10.1016/j.bbrc.2021.07.026

PMID: 34271433
Sample: serum
METABOLIC BRAIN DISEASE (2021) IF: 3.584
Dichloroacetic acid-induced dysfunction in rat hippocampus and the protective effect of curcumin

DOI: 10.1007/s11011-020-00657-5

PMID: 33411217
Sample: hippocampal tissues
NEUROSCIENCE (2018) IF: 3.59
Inhibiting Succinate Dehydrogenase by Dimethyl Malonate Alleviates Brain Damage in a Rat Model of Cardiac Arrest

DOI: 10.1016/j.neuroscience.2018.09.041

PMID: 30300703
Sample: Serum
NEUROSCIENCE (2021) IF: 3.59
Hydrogen Alleviates Neuronal Injury and Neuroinflammation Induced by Microglial Activation via the Nuclear Factor Erythroid 2-related Factor 2 Pathway in Sepsis-associated Encephalopathy

DOI: 10.1016/j.neuroscience.2021.05.003

PMID: 33992722
Sample: Cell culture supernatant,Tissue homogenate(Brain)
NEUROSCIENCE (2022) IF: 3.59
High Environmental Temperature: Insights into Behavioural, Neurodevelopmental and Gut Microbiome Changes Following Gestational Exposure in Rats

DOI: 10.1016/j.neuroscience.2022.02.026

PMID: 35231581
Sample: Brain
BMC IMMUNOLOGY (2022) IF: 3.594
NLRP3 inflammasome up-regulates major histocompatibility complex class I expression and promotes inflammatory infiltration in polymyositis

DOI: 10.1186/s12865-022-00515-2

PMID: 35965334
Sample: serum,muscle
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2020) IF: 3.606
Neuroprotective role of gallic acid in aflatoxin B1‐induced behavioral abnormalities in rats

DOI: 10.1002/jbt.22684

Sample: cerebrum tissue lysate supernatant
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2020) IF: 3.606
Assessment of the protective and therapeutic effect of melatonin against thioacetamide‐induced acute liver damage

DOI: 10.1002/jbt.22450

Sample: Tissue homogenate
PHYTOMEDICINE (2018) IF: 3.61
Epigallocatechin gallate attenuates mitochondrial DNA-induced inflammatory damage in the development of ventilator-induced lung injury

DOI: 10.1016/j.phymed.2018.05.017

Sample: Tissue homogenate
Frontiers in Endocrinology (2020) IF: 3.644
Guizhi Fuling Wan, Chinese Herbal Medicine, Ameliorates Insulin Sensitivity in PCOS Model Rats With Insulin Resistance via Remodeling Intestinal Homeostasis

DOI: 10.3389/fendo.2020.00575

PMID: 32973686
Sample: Plasma
LIFE SCIENCES (2020) IF: 3.647
Lauric acid ameliorates lipopolysaccharide (LPS)-induced liver inflammation by mediating TLR4/MyD88 pathway in Sprague Dawley (SD) rats

DOI: 10.1016/j.lfs.2020.118750

PMID: 33188836
Sample: Serum
LIFE SCIENCES (2020) IF: 3.647
Curcumin and LOXblock-1 ameliorate ischemia-reperfusion induced inflammation and acute kidney injury by suppressing the semaphorin-plexin pathway.

DOI: 10.1016/j.lfs.2020.118016

Sample: Serum
LIFE SCIENCES (2020) IF: 3.647
Attenuation of chronic arsenic neurotoxicity via melatonin in male offspring of maternal rats exposed to arsenic during conception: Involvement of oxidative DNA damage and inflammatory signaling cascades

DOI: 10.1016/j.lfs.2020.118876

PMID: 33310035
Sample: Tissue homogenate
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2022) IF: 3.652
Rivastigmine ameliorates indomethacin experimentally induced gastric mucosal injury via activating α7nAChR with inhibiting oxidative stress and apoptosis

DOI: 10.1002/jbt.23147

Sample: gastric tissue
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2022) IF: 3.652
Renoprotective effect of vinpocetine against ischemia/reperfusion injury: Modulation of NADPH oxidase/Nrf2, IKKβ/NF-κB p65, and cleaved caspase-3 expressions

DOI: 10.1002/jbt.23046

PMID: 35315168
Sample: Renal
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2021) IF: 3.652
Biochemical and histological alterations of doxorubicin-induced neurotoxicity in rats: Protective role of luteolin

DOI: 10.1002/jbt.22962

PMID: 34766659
Sample: brain
JOURNAL OF FOOD BIOCHEMISTRY (2022) IF: 3.654
Anti-inflammatory potential of berberine-rich extract via modulation of inflammation biomarkers

DOI: 10.1111/jfbc.14389

PMID: 36121315
Sample: serum
IMMUNOLOGICAL INVESTIGATIONS (2020) IF: 3.657
Overexpression of lncRNA HULC Attenuates Myocardial Ischemia/reperfusion Injury in Rat Models and Apoptosis of Hypoxia/reoxygenation Cardiomyocytes via Targeting miR-377-5p through NLRP3/Caspase‑1/IL‑1β Signaling Pathway Inhibition

DOI: 10.1080/08820139.2020.1791178

Sample: Cell culture supernatant
BMC Complementary and Alternative Medicine (2022) IF: 3.659
Neuroprotective effects of Lippia javanica (Burm.F.) Spreng. Herbal tea infusion on Lead-induced oxidative brain damage in Wistar rats

DOI: 10.1186/s12906-021-03471-3

PMID: 34983490
Sample: brain tissue
BMC Complementary and Alternative Medicine (2021) IF: 3.659
Lippia javanica (Zumbani) herbal tea infusion attenuates allergic airway inflammation via inhibition of Th2 cell activation and suppression of oxidative stress

DOI: 10.1186/s12906-021-03361-8

PMID: 34225706
Sample: serum
BMC Complementary and Alternative Medicine (2021) IF: 3.659
Effect of the standard herbal preparation, STW5, treatment on dysbiosis induced by dextran sodium sulfate in experimental colitis

DOI: 10.1186/s12906-021-03337-8

PMID: 34103031
Sample: colon
AMERICAN JOURNAL OF CHINESE MEDICINE (2020) IF: 3.682
Corydalis saxicola Alkaloids Attenuate Cisplatin-Induced Neuropathic Pain by Reducing Loss of IENF and Blocking TRPV1 Activation

DOI: 10.1142/S0192415X20500214

PMID: 32138533
Sample: Serum
JOURNAL OF ETHNOPHARMACOLOGY (2020) IF: 3.69
Anti-angiogenic effect of Shikonin in rheumatoid arthritis by downregulating PI3K/AKT and MAPKs signaling pathways

DOI: 10.1016/j.jep.2020.113039

PMID: 32497675
Sample: Serum,Cell culture supernatant
CELL CYCLE (2020) IF: 3.699
Knockdown of circular RNA circMAT2B reduces oxygen-glucose deprivation-induced inflammatory injury in H9c2 cells through up-regulating miR-133

DOI: 10.1080/15384101.2020.1814025

PMID: 32897801
Sample: Cell culture supernatant
Diagnostics (2022) IF: 3.706
Combination Antiretroviral Therapy (cART) in Diabetes Exacerbates Diabetogenic Effects on Hippocampal Microstructure, Neurogenesis and Cytokine Perturbation in Male Sprague Dawley Rats

DOI: 10.3390/diagnostics12040905

PMID: 35453953
Sample: brain
Frontiers in Neuroscience (2020) IF: 3.707
Potent Natural Antioxidant Carveol Attenuates MCAO-Stress Induced Oxidative, Neurodegeneration by Regulating the Nrf-2 Pathway

DOI: 10.3389/fnins.2020.00659

Sample: Tissue homogenate
NEUROSCIENCE (2023) IF: 3.708
Essential Trace Elements Prevent the Impairment in the Retention Memory, Cerebral Cortex, and Cerebellum Damage in Male Rats Exposed to Quaternary Metal Mixture by Up-regulation, of Heme Oxygynase-1 and Down-regulation of Nuclear Factor Erythroid 2-relate

DOI: 10.1016/j.neuroscience.2023.01.002

PMID: 36646412
Sample: cerebral cortex,cerebellum
BIOLOGICAL TRACE ELEMENT RESEARCH (2022) IF: 3.738
Candesartan Protects Against Cadmium-Induced Hepatorenal Syndrome by Affecting Nrf2, NF-κB, Bax/Bcl-2/Cyt-C, and Ang II/Ang 1–7 Signals

DOI: 10.1007/s12011-022-03286-4

Sample: kidney
JOURNAL OF PERIODONTOLOGY (2020) IF: 3.742
Melatonin improves periodontitis‐induced kidney damages by decreasing inflammatory stress and apoptosis in rats

DOI: 10.1002/JPER.20-0434

Sample: kidney
BIOMEDICINE & PHARMACOTHERAPY (2019) IF: 3.743
HMGB1/RAGE pro-inflammatory axis promotes vascular endothelial cell apoptosis in limb ischemia/reperfusion injury

DOI: 10.1016/j.biopha.2019.109005

Sample: serum,Human Umbilical Vein Endothelial Cells (HUVE
BIOMEDICINE & PHARMACOTHERAPY (2019) IF: 3.743
Baicalein administered in the subacute phase ameliorates ischemia-reperfusion-induced brain injury by reducing neuroinflammation and neuronal damage

DOI: 10.1016/j.biopha.2019.109102

Sample: brain
PLoS One (2022) IF: 3.752
Short chain fatty acid, acetate restores ovarian function in experimentally induced PCOS rat model

DOI: 10.1371/journal.pone.0272124

PMID: 35881588
Sample: ovarian,blood
MEDIATORS OF INFLAMMATION (2020) IF: 3.758
Paeonol Attenuates Methotrexate-Induced Cardiac Toxicity in Rats by Inhibiting Oxidative Stress and Suppressing TLR4-Induced NF-κB Inflammatory Pathway

DOI: 10.1155/2020/8641026

Sample: Soil,Water,Oil,Plant Tissue,Plant Fluid,Antibody,F
Heliyon (2022) IF: 3.776
Mangrove fruit (Bruguiera gymnorhiza) increases circulating GLP-1 and PYY, modulates lipid profiles, and reduces systemic inflammation by improving SCFA levels in obese wistar rats

DOI: 10.1016/j.heliyon.2022.e10887

Sample: blood,caecum
Heliyon (2020) IF: 3.776
In vivo exposure to codeine induces reproductive toxicity: role of HER2 and p53/Bcl-2 signaling pathway

DOI: 10.1016/j.heliyon.2020.e05589

Sample: testicular
CERAMICS INTERNATIONAL (2020) IF: 3.83
Synthesis and characterization of barium-doped bioactive glass with potential anti-inflammatory activity

DOI: 10.1016/j.ceramint.2020.11.068

Sample: Cell culture supernatant
Frontiers in Pharmacology (2018) IF: 3.831
PSTPIP2 Inhibits the Inflammatory Response and Proliferation of Fibroblast-Like Synoviocytes in vitro

DOI: 10.3389/fphar.2018.01432

PMID: 30564127
Sample: Serum,Cell culture supernatant
INFLAMMOPHARMACOLOGY (2019) IF: 3.838
leaf extracts attenuate Complete Freund’s adjuvant-induced arthritis in Wistar rats via modulation of inflammatory and oxidative stress biomarkers

DOI: 10.1007/s10787-019-00596-3

Sample: Serum
MOLECULAR AND CELLULAR BIOCHEMISTRY (2023) IF: 3.842
Plantain-based diet decreases oxidative stress and inflammatory markers in the testes of rats exposed to atrazine

DOI: 10.1007/s11010-022-04639-2

Sample: Serum
MOLECULAR AND CELLULAR BIOCHEMISTRY (2023) IF: 3.842
Lansoprazole attenuates cyclophosphamide-induced cardiopulmonary injury by modulating redox-sensitive pathways and inflammation

DOI: 10.1007/s11010-023-04662-x

Sample: heart,lung
PEPTIDES (2023) IF: 3.867
Irisin prevents hypoxic-ischemic brain damage in rats by inhibiting oxidative stress and protecting the blood-brain barrier

DOI: 10.1016/j.peptides.2023.170945

Sample: brain
ENDOCRINE (2022) IF: 3.925
Acetate restores hypothalamic-adipose kisspeptin status in a rat model of PCOS by suppression of NLRP3 immunoreactivity

DOI: 10.1007/s12020-022-03191-9

PMID: 36114434
Sample: hypothalamic tissue,VAT
Annals of Translational Medicine (2022) IF: 3.932
MMP2/9 downregulation is responsible for hepatic function recovery in cirrhotic rats following associating liver partition and portal vein ligation for staged hepatectomy

DOI: 10.21037/atm-22-1312

Sample: serum
Annals of Translational Medicine (2021) IF: 3.932
Conjugated linoleic acid prompts bone formation in ovariectomized osteoporotic rats and weakens osteoclast formation after treatment with ultraviolet B

DOI: 10.21037/atm-21-934

PMID: 33850900
Sample: Serum
INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 3.943
Klotho ameliorates the onset and progression of cataract via suppressing oxidative stress and inflammation in the lens in streptozotocin-induced diabetic rats

DOI: 10.1016/j.intimp.2020.106582

PMID: 32438076
Sample: Plasma
INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 3.943
Inhibition of macrophage migration inhibitory factor prevents thyroid dysfunction in pregnant rats with acute pancreatitis

DOI: 10.1016/j.intimp.2020.106771

PMID: 32683302
Sample: Serum
INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 3.943
Betulin alleviates on myocardial inflammation in diabetes mice via regulating Siti1/NLRP3/NF-κB pathway

DOI: 10.1016/j.intimp.2020.106653

Sample: H9c2 cell
THROMBOSIS RESEARCH (2021) IF: 3.944
Brain-derived extracellular vesicles mediated coagulopathy, inflammation and apoptosis after sepsis

DOI: 10.1016/j.thromres.2021.09.014

PMID: 34583153
Sample: blood
APOPTOSIS (2018) IF: 3.967
MiRNA-126 expression inhibits IL-23R mediated TNF-α or IFN-γ production in fibroblast-like synoviocytes in a mice model of collagen-induced rheumatoid arthritis

DOI: 10.1007/s10495-018-1474-7

Sample: Serum
Obesity (2019) IF: 3.969
Liraglutide Lowers Body Weight Set Point in DIO Rats and its Relationship with Hypothalamic Microglia Activation

DOI: 10.1002/oby.22666

PMID: 31773909
Sample: Cell culture supernatant
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2018) IF: 3.974
Cold stress provokes lung injury in rats co-exposed to fine particulate matter and lipopolysaccharide

DOI: 10.1016/j.ecoenv.2018.10.064

PMID: 30384172
Sample: Tissue homogenate
NEUROCHEMISTRY INTERNATIONAL (2019) IF: 3.994
Lercanidipine boosts the efficacy of mesenchymal stem cell therapy in 3-NP-induced Huntington's disease model rats via modulation of the calcium/calcineurin/NFATc4 and Wnt/β-catenin signalling pathways

DOI: 10.1016/j.neuint.2019.104548

Sample: brain
Scientific Reports (2020) IF: 3.998
Quercetin liposomes ameliorate streptozotocin-induced diabetic nephropathy in diabetic rats

DOI: 10.1038/s41598-020-59411-7

Sample: serum
Scientific Reports (2020) IF: 3.998
Effects and safety of Psilocybe cubensis and Panaeolus cyanescens magic mushroom extracts on endothelin-1-induced hypertrophy and cell injury in cardiomyocytes

DOI: 10.1038/s41598-020-79328-5

PMID: 33339902
Sample: Cell culture supernatant
JOURNAL OF SURGICAL RESEARCH (2013) IF: 2.018
Dobutamine-mediated heme oxygenase-1 induction via PI3K and p38 MAPK inhibits high mobility group box 1 protein release and attenuates rat myocardial ischemia/reperfusion injury in vivo

DOI: 10.1016/j.jss.2013.02.051

Sample: Tissue homogenate
BMC Complementary and Alternative Medicine (2015) IF: 2.02
Edible Bird’s Nest attenuates high fat diet-induced oxidative stress and inflammation via regulation of hepatic antioxidant and inflammatory genes

DOI: 10.1186/s12906-015-0843-9

Sample: Serum
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2019) IF: 2.041
The modulatory effects of exercise on the inflammatory and apoptotic markers in rats with 1,2-dimethylhydrazine-induced colorectal cancer

DOI: 10.1139/cjpp-2019-0329

Sample: serum
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2021) IF: 2.043
miR-484 targeting of Yap1-induced LPS-inhibited proliferation, and promoted apoptosis and inflammation in cardiomyocyte

DOI: 10.1093/bbb/zbaa009

PMID: 33604630
Sample: Cell culture supernatant(H9c2 cells)
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2020) IF: 2.05
The protective effect of fenofibrate, triptorelin, and their combination against premature ovarian failure in rats

DOI: 10.1007/s00210-020-01975-2

PMID: 32924068
Sample: Serum
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2020) IF: 2.05
Protective effect of oleuropein on ketamine-induced cardiotoxicity in rats

DOI: 10.1007/s00210-020-01870-w

PMID: 32383030
Sample: Serum
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2020) IF: 2.05
Metformin attenuated histopathological ocular deteriorations in a streptozotocin-induced hyperglycemic rat model

DOI: 10.1007/s00210-020-01989-w

PMID: 33047165
Sample: Serum
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2020) IF: 2.05
Effects of vitamin B12 on methotrexate hepatotoxicity: evaluation of receptor-interacting protein (RIP) kinase

DOI: 10.1007/s00210-020-01992-1

PMID: 33052426
Sample: Tissue homogenate
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2019) IF: 2.058
Protective effect of dipeptidyl peptidase-4 inhibitors in testicular torsion/detorsion in rats: a possible role of HIF-1α and nitric oxide

DOI: 10.1007/s00210-019-01765-5

Sample: testicular
Evidence-based Complementary and Alternative Medicine (2018) IF: 2.064
Sheng-Di-Da-Huang Decoction Inhibited Inflammation Expressed in Microglia after Intracerebral Hemorrhage in Rats

DOI: 10.1155/2018/6470534

Sample: brain tissues
Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology (2021) IF: 2.064
Electroacupuncture restores intestinal mucosal barrier through TLR4/NF-κB p65 pathway in functional dyspepsia-like rats

DOI: 10.1002/ar.24800

PMID: 34713984
Sample: Blood
HUMAN & EXPERIMENTAL TOXICOLOGY (2020) IF: 2.067
Sildenafil ameliorates Alzheimer disease via the modulation of vascular endothelial growth factor and vascular cell adhesion molecule-1 in rats:

DOI: 10.1177/0960327120960775

Sample: Tissue homogenate
Brain and Behavior (2020) IF: 2.091
Fetal exposure to dichloroacetic acid and impaired cognitive function in the adulthood

DOI: 10.1002/brb3.1801

Sample: hippocampal tissue
Molecular Medicine Reports (2020) IF: 2.1
Pretreatment with the ALDH2 activator Alda‑1 protects rat livers from ischemia/reperfusion injury by inducing autophagy

DOI: 10.3892/mmr.2020.11312

PMID: 32705206
Sample: Serum
ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY (2019) IF: 2.11
Evaluating the effects of Juglans regia L. extract on hyperglycaemia and insulin sensitivity in experimental type 2 diabetes in rat

DOI: 10.1080/13813455.2019.1668018

Sample: Plasma
INFLAMMATION RESEARCH (2014) IF: 2.143
Effect of retinoic acid on the function of lipopolysaccharide-stimulated bone marrow stromal cells grown on titanium surfaces

DOI: 10.1007/s00011-014-0784-7

Sample: Cell culture supernatant
Iranian Journal of Basic Medical Sciences (2020) IF: 2.146
Effect of doxycycline and meloxicam on cytokines, brain-derived neurotrophic factor, matrix metalloproteinase-3, tissue inhibitor of metalloproteinase-3 and cyclooxygenase-2 in brain

DOI: 10.22038/ijbms.2020.45193.10527

PMID: 33149866
Sample: Tissue homogenate
NEUROSCIENCE LETTERS (2018) IF: 2.159
Rutin attenuates neurobehavioral deficits, oxidative stress, neuro-inflammation and apoptosis in fluoride treated rats

DOI: 10.1016/j.neulet.2018.06.023

Sample: Tissue homogenate
HUMAN & EXPERIMENTAL TOXICOLOGY (2019) IF: 2.171
Hepatorenal protective effects of protocatechuic acid in rats administered with anticancer drug methotrexate:

DOI: 10.1177/0960327119871095

Sample: hepatic and renal
Therapeutic Advances in Endocrinology and Metabolism (2020) IF: 2.173
Plant-derived oleanolic acid ameliorates markers of subclinical inflammation and innate immunity activation in diet-induced pre-diabetic rats:

DOI: 10.1177/2042018820935771

Sample: Plasma
BMC Cardiovascular Disorders (2022) IF: 2.174
Increased protein phosphatase 5 expression in inflammation-induced left ventricular dysfunction in rats

DOI: 10.1186/s12872-022-02977-z

Sample: serum
Biomed Research International (2019) IF: 2.197
MiR-21-3p Plays a Crucial Role in Metabolism Alteration of Renal Tubular Epithelial Cells during Sepsis Associated Acute Kidney Injury via AKT/CDK2-FOXO1 Pathway

DOI: 10.1155/2019/2821731

Sample: serum
Biomed Research International (2019) IF: 2.197
Galangin Suppresses Renal Inflammation via the Inhibition of NF-κB, PI3K/AKT and NLRP3 in Uric Acid Treated NRK-52E Tubular Epithelial Cells

DOI: 10.1155/2019/3018357

PMID: 31240210
Sample: Cell culture supernatant
Open Medicine (2022) IF: 2.199
Lidocaine ameliorates chronic constriction injury-induced neuropathic pain through regulating M1/M2 microglia polarization

DOI: 10.1515/med-2022-0480

Sample: HAPI cell
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2018) IF: 2.21
The pectin–insulin patch application prevents the onset of peripheral neuropathy-like symptoms in streptozotocin-induced diabetic rats

DOI: 10.1139/cjpp-2018-0415

Sample: Plasma
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2018) IF: 2.21
Histopathological and biochemical changes in the development of nonalcoholic fatty liver disease induced by high-sucrose diet at different times

DOI: 10.1139/cjpp-2018-0353

PMID: 30388378
Sample: Serum
ARCHIVES OF MEDICAL RESEARCH (2021) IF: 2.235
Effect of Pramipexole on Inflammatory Response in Central Nervous System of Parkinson's Disease Rat Model

DOI: 10.1016/j.arcmed.2021.06.007

PMID: 34218945
Sample: brain
Computational and Mathematical Methods in Medicine (2021) IF: 2.238
Mild Hypothermia Therapy Lowers the Inflammatory Level and Apoptosis Rate of Myocardial Cells of Rats with Myocardial Ischemia-Reperfusion Injury via the NLRP3 Inflammasome Pathway

DOI: 10.1155/2021/6415275

PMID: 34422094
Sample: H9c2 cell
Toxicology Research (2020) IF: 2.283
Microscopic and biochemical changes on liver and kidney of Wistar rats on combination antiretroviral therapy: the impact of naringenin and quercetin

DOI: 10.1093/toxres/tfaa060

Sample: liver
SOUTH AFRICAN JOURNAL OF BOTANY (2021) IF: 2.315
Investigation of therapeutic potential of three endemic Cirsium species for global health problem obesity

DOI: 10.1016/j.sajb.2021.05.004

Sample: Serum
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2019) IF: 2.336
Hypoxia‐inducible factor 1 alpha and nuclear‐related receptor 1 as targets for neuroprotection by albendazole in a rat rotenone model of Parkinson's disease

DOI: 10.1111/1440-1681.13162

Sample: substantia nigra
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2017) IF: 2.341
SIRT1 exerts neuroprotective effects by attenuating cerebral ischemia/reperfusion-induced injury via targeting p53/microRNA-22

DOI: 10.3892/ijmm.2016.2806

Sample: Tissue homogenate
JOURNAL OF CHEMICAL NEUROANATOMY (2020) IF: 2.353
MiR-497 promotes microglia activation and proinflammatory cytokines production in chronic unpredictable stress-induced depression via targeting FGF2

DOI: 10.1016/j.jchemneu.2020.101872

PMID: 33068702
Sample: Tissue homogenate
PeerJ (2019) IF: 2.353
Effect of heat-killed Streptococcus thermophilus on type 2 diabetes rats

DOI: 10.7717/peerj.7117

Sample: serum
Metabolic Syndrome and Related Disorders (2022) IF: 2.363
Naringenin Prevents Inflammation, Apoptosis, and DNA Damage in Potassium Oxonate-Induced Hyperuricemia in Rat Liver Tissue: Roles of Cytochrome C, NF-κB, Caspase-3, and 8-Hydroxydeoxyguanosine

DOI: 10.1089/met.2022.0028

PMID: 35796694
Sample: Liver tissue
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016) IF: 2.371
Necrostatin-1 protects against oleic acid-induced acute respiratory distress syndrome in rats

DOI: 10.1016/j.bbrc.2016.08.163

Sample: Bronchoalveolar Lavage Fluid
CLINICAL RHEUMATOLOGY (2020) IF: 2.394
Investigation of the efficacy of daidzein in experimental knee osteoarthritis-induced with monosodium iodoacetate in rats

DOI: 10.1007/s10067-020-04958-z

PMID: 32103372
Sample: Serum
AUTOIMMUNITY (2019) IF: 2.403
The changes in immune cell concentration during the progression of pre-diabetes to type 2 diabetes in a high-fat high-carbohydrate diet-induced pre-diabetic rat model

DOI: 10.1080/08916934.2019.1575820

PMID: 30776930
Sample: Plasma
Canadian Respiratory Journal (2022) IF: 2.409
Chitosan-Coated Solid Lipid Nano-Encapsulation Improves the Therapeutic Antiairway Inflammation Effect of Berberine against COPD in Cigarette Smoke-Exposed Rats

DOI: 10.1155/2022/8509396

PMID: 35465190
Sample: BALF
METABOLIC BRAIN DISEASE (2019) IF: 2.411
attenuates hydrogen peroxide induced oxidative toxicity in PC12 cells

DOI: 10.1007/s11011-019-00440-1

Sample: PC12 cells
EXPERIMENTAL PHYSIOLOGY (2020) IF: 2.431
Combination of quercetin and exercise training attenuates depression in rats with 1,2‐dimethylhydrazine‐induced colorectal cancer: Possible involvement of inflammation and BDNF signalling

DOI: 10.1113/EP088605

Sample: Serum,Tissue homogenate
Journal of Integrative Medicine-JIM (2020) IF: 2.446
Effects of co-administration of Ganoderma terpenoid extract with chloroquine on inflammatory markers and antioxidant status in Plasmodium berghei-infected mice

DOI: 10.1016/j.joim.2020.08.002

Sample: serum
Experimental and Therapeutic Medicine (2021) IF: 2.447
MicroRNA‑16 regulates lipopolysaccharide‑induced inflammatory factor expression by targeting TLR4 in normal human bronchial epithelial cells

DOI: 10.3892/etm.2021.10414

Sample: blood
Experimental and Therapeutic Medicine (2019) IF: 2.447
H2S attenuates sepsis‑induced cardiac dysfunction via a PI3K/Akt‑dependent mechanism

DOI: 10.3892/etm.2019.7440

Sample: serum
Experimental and Therapeutic Medicine (2021) IF: 2.447
Graphene oxide induces dose‑dependent lung injury in rats by regulating autophagy

DOI: 10.3892/etm.2021.9893

Sample: Tissue homogenate
Experimental and Therapeutic Medicine (2021) IF: 2.447
Gadolinium chloride pre‑treatment reduces the inflammatory response and preserves intestinal barrier function in a rat model of sepsis

DOI: 10.3892/etm.2021.10577

Sample: serum,intestinal tissue
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS (2021) IF: 2.457
Remote Ischemic Perconditioning Ameliorates Myocardial Ischemia and Reperfusion-Induced Coronary Endothelial Dysfunction and Aortic Stiffness in Rats:

DOI: 10.1177/10742484211031327

Sample: plasma
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017) IF: 2.466
Umbilical cord-derived mesenchymal stem cells alleviated inflammation and inhibited apoptosis in interstitial cystitis via AKT/mTOR signaling pathway

DOI: 10.1016/j.bbrc.2017.11.072

Sample: Tissue homogenate
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017) IF: 2.466
Edaravone attenuates lipopolysaccharide-induced acute respiratory distress syndrome associated early pulmonary fibrosis via amelioration of oxidative stress and transforming growth factor-β1/Smad3 signaling

DOI: 10.1016/j.bbrc.2017.10.165

Sample: Serum
TISSUE & CELL (2021) IF: 2.466
Contraceptive potential of Andrographis paniculata is via androgen suppression and not induction of oxidative stress in male Wistar rats

DOI: 10.1016/j.tice.2021.101632

PMID: 34479074
Sample: testicular
Journal of Ovarian Research (2019) IF: 2.469
Abnormal expression of HSP70 may contribute to PCOS pathology

DOI: 10.1186/s13048-019-0548-7

Sample: serum
ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2022) IF: 2.471
Healing Potential of Propolis Extract–Passiflora edulis Seed Oil Emulgel Against Excisional Wound: Biochemical, Histopathological, and Cytokines Level Evidence

DOI: 10.1089/adt.2022.075

Sample: Skin samples
ACTA HISTOCHEMICA (2022) IF: 2.479
Potential stem cell—Conditioned medium and their derived exosomes versus omeprazole in treatment of experimental model of gastric ulcer

DOI: 10.1016/j.acthis.2022.151896

Sample: gastric tissue.
BMC Complementary and Alternative Medicine (2019) IF: 2.479
In vitro anti-allergic activity of Moringa oleifera Lam. extracts and their isolated compounds

DOI: 10.1186/s12906-019-2776-1

Sample: RBL-2H3 cell
Cardiovascular Engineering and Technology (2021) IF: 2.495
The Mitochondrial-Derived Peptide MOTS-c Attenuates Oxidative Stress Injury and the Inflammatory Response of H9c2 Cells Through the Nrf2/ARE and NF-κB Pathways

DOI: 10.1007/s13239-021-00589-w

PMID: 34859377
Sample: H9c2 cell
GENE (2018) IF: 2.498
MicroRNA-24 regulates vascular remodeling via inhibiting PDGF-BB pathway in diabetic rat model

DOI: 10.1016/j.gene.2018.03.056

Sample: Tissue homogenate
Iranian Journal of Basic Medical Sciences (2022) IF: 2.532
Cobalt exposure triggers impairments in cognitive and anxiety-like behaviors, brain oxidative stress and inflammation, and hippocampo-amygdala histomorphological alterations: Protective role of aqueous Prosopis africana seed extract

DOI: 10.22038/IJBMS.2022.65689.14456

Sample: Brain
BIOSCIENCE REPORTS (2019) IF: 2.535
Shenqi Fuzheng Injection impairs bile duct ligation-induced cholestatic liver injury in vivo

DOI: 10.1042/BSR20180787

PMID: 30610157
Sample: Tissue homogenate
Cardiovascular Therapeutics (2020) IF: 2.538
Bredemolic Acid Improves Cardiovascular Function and Attenuates Endothelial Dysfunction in Diet-Induced Prediabetes: Effects on Selected Markers

DOI: 10.1155/2020/1936406

PMID: 32117470
Sample: Plasma,Tissue homogenate
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018) IF: 2.559
Serum thyroid hormones levels are significantly decreased in pregnant rats with acute pancreatitis

DOI: 10.1016/j.bbrc.2018.09.180

PMID: 30286956
Sample: Serum
TISSUE & CELL (2022) IF: 2.586
Resveratrol alleviates bleomycin-induced pulmonary fibrosis by inhibiting epithelial-mesenchymal transition and down-regulating TLR4/NF-κB and TGF-β1/smad3 signalling pathways in rats

DOI: 10.1016/j.tice.2022.101953

PMID: 36228366
Sample: Lung tissue
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH (2017) IF: 2.59
Angiotensin-(1-7) relieved renal injury induced by chronic intermittent hypoxia in rats by reducing inflammation, oxidative stress and fibrosis

DOI: 10.1590/1414-431X20165594

Sample: Plasma
BMC Pharmacology & Toxicology (2022) IF: 2.605
Pharmacological evaluation of newly synthesized organotin IV complex for antiulcer potential

DOI: 10.1186/s40360-022-00596-0

PMID: 35906691
Sample: Stomach tissue
RENAL FAILURE (2019) IF: 2.606
Diabetes aggravates renal ischemia and reperfusion injury in rats by exacerbating oxidative stress, inflammation, and apoptosis

DOI: 10.1080/0886022X.2019.1643737

Sample: renal
EUROPEAN JOURNAL OF ORAL SCIENCES (2021) IF: 2.612
Effect of ischemic preconditioning on radiation damage to the submandibular gland in rats

DOI: 10.1111/eos.12785

PMID: 33786924
Sample: Tissue homogenate
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2020) IF: 2.614
Tiliacora triandra extract and its major constituent attenuates diabetic kidney and testicular impairment by modulating redox imbalance and pro‐inflammatory responses in rats

DOI: 10.1002/jsfa.10779

Sample: Tissue homogenate
Dose-Response (2022) IF: 2.623
Dose Dependent Effects of Breynia cernua Against the Paraquat Induced Parkinsonism like Symptoms in Animals’ Model: In Vitro, In Vivo and Mechanistic Studies

DOI: 10.1177/15593258221125478

Sample: brain tissue
Dose-Response (2022) IF: 2.623
Biochemical Investigation of Therapeutic Potentials of Plant-Based Bioactive Compounds as Stimulators of Glucagon like peptide-1 Secretion :

DOI: 10.1177/15593258221114184

Sample: serum,Pancreatic,intestinal tissue
Evidence-based Complementary and Alternative Medicine (2021) IF: 2.63
Proteomic Analysis and In Vivo Studies Reveal the Potential Gastroprotective Effects of CHCl3 and Aqueous Extracts of Ficus palmata

DOI: 10.1155/2021/6613140

Sample: Tissue homogenate
Evidence-based Complementary and Alternative Medicine (2022) IF: 2.63
Molecular Mechanism of Traditional Chinese Ointment of Xuzhou Qufu Shengji in Infected Wounds

DOI: 10.1155/2022/4116563

PMID: 35069758
Sample: skin
ENVIRONMENTAL TOXICOLOGY (2019) IF: 2.649
Cadmium and nickel co‐exposure exacerbates genotoxicity and not oxido‐inflammatory stress in liver and kidney of rats: Protective role of omega‐3 fatty acid

DOI: 10.1002/tox.22860

Sample: Tissue homogenate
BIOMARKERS (2022) IF: 2.658
Gastro-protective effect of Artemisia sieberi essential oil against ethanol-induced ulcer in rats as revealed via biochemical, histopathological and metabolomics analysis

DOI: 10.1080/1354750X.2021.2025428

PMID: 34978233
Sample: stomach tissue
BIOMARKERS (2022) IF: 2.663
Justicia carnea extracts ameliorated hepatocellular damage in streptozotocin-induced type 1 diabetic male rats via decrease in oxidative stress, inflammation and increasing other risk markers

DOI: 10.1080/1354750X.2022.2157487

Sample: liver
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (2018) IF: 2.673
Orthosiphon stamineus (Misai Kucing) ameliorated postmenopausal osteoporosis in rat model

DOI: 10.1097/GME.0000000000000980

Sample: serum
EXPERIMENTAL BIOLOGY AND MEDICINE (2020) IF: 2.691
Protective effect of exogenous hydrogen sulfide on diaphragm muscle fibrosis in streptozotocin-induced diabetic rats:

DOI: 10.1177/1535370220931038

Sample: Tissue homogenate
FEBS Open Bio (2021) IF: 2.693
Salvinorin A inhibits ovalbumin-stimulated allergic rhinitis and RBL-2H3 cells degranulation

DOI: 10.1002/2211-5463.13219

PMID: 34092045
Sample: RBL-2H4 cells
Journal of Experimental Zoology Part A-Ecological and Integrative Physiology (2022) IF: 2.693
Molecular mechanisms underlying ameliorative impact of melatonin against age-dependent chronic arsenic toxicity in rats' brains

DOI: 10.1002/jez.2603

Sample: brain
Iranian Journal of Basic Medical Sciences (2021) IF: 2.699
L-Carnitine ameliorates the liver by regulating alpha-SMA, iNOS, HSP90, HIF-1alpha, and RIP1 expressions of CCL4-toxic rats

DOI: 10.22038/IJBMS.2020.47711.10990

PMID: 33953857
Sample: Serum
Brain and Behavior (2021) IF: 2.708
Melatonin salvages lead-induced neuro-cognitive shutdown, anxiety, and depressive-like symptoms via oxido-inflammatory and cholinergic mechanisms

DOI: 10.1002/brb3.2227

PMID: 34087957
Sample: brain
JOURNAL OF FOOD BIOCHEMISTRY (2022) IF: 2.72
Effect of coconut water and milk on heat stress-induced gastrointestinal tract dysmotility in rats: Role of oxidative stress and inflammatory response

DOI: 10.1111/jfbc.14129

PMID: 35298033
Sample: stomach
JOURNAL OF FOOD BIOCHEMISTRY (2021) IF: 2.72
Chlorogenic acid co-administration abates tamoxifen-mediated reproductive toxicities in male rats: An experimental approach

DOI: 10.1111/jfbc.13615

PMID: 33491243
Sample: Tissue homogenate
EUROPEAN JOURNAL OF PHARMACOLOGY (2016) IF: 2.73
The protective role of neuregulin-1: A potential therapy for sepsis-induced cardiomyopathy

DOI: 10.1016/j.ejphar.2016.06.042

Sample: Serum
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY (2021) IF: 2.73
Neuroprotective role of camphor against ciprofloxacin induced depression in rats: modulation of Nrf-2 and TLR4

DOI: 10.1080/08923973.2021.1905658

PMID: 34032546
Sample: Tissue homogenate
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY (2021) IF: 2.73
Ameliorating effect of leukotriene receptor antagonist in multi-organ toxicity induced in rat offspring, a possible role for epidermal growth factor

DOI: 10.1080/08923973.2021.1878213

PMID: 33504223
Sample: Tissue homogenate
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2020) IF: 2.734
Folate receptor-β targeted cholesterol-chitosan nanocarrier for treatment of rheumatoid arthritis: An animal study

DOI: 10.1016/j.jddst.2020.101946

Sample: serum
PLoS One (2020) IF: 2.74
Associations of inflammatory markers with impaired left ventricular diastolic and systolic function in collagen-induced arthritis

DOI: 10.1371/journal.pone.0230657

PMID: 32208438
Sample: Serum
FUNDAMENTAL & CLINICAL PHARMACOLOGY (2021) IF: 2.748
Angiotensin aldosterone inhibitors improve survival and ameliorate kidney injury induced by sepsis through suppression of inflammation and apoptosis

DOI: 10.1111/fcp.12718

PMID: 34309069
Sample: serum
FUNDAMENTAL & CLINICAL PHARMACOLOGY (2020) IF: 2.754
Ameliorative effect of Ozagrel, a thromboxane A2 synthase inhibitor, in hyperhomocysteinemia‐induced experimental vascular cognitive impairment and dementia

DOI: 10.1111/fcp.12610

Sample: Serum
FUNDAMENTAL & CLINICAL PHARMACOLOGY (2020) IF: 2.754
Ameliorative effect of Ozagrel, a thromboxane A2 synthase inhibitor, in hyperhomocysteinemia‐induced experimental vascular cognitive impairment and dementia

DOI: 10.1111/fcp.12610

Sample: Tissue homogenate
Pharmacological Reports (2020) IF: 2.754
Agomelatine prevents indomethacin-induced gastric ulcer in rats

DOI: 10.1007/s43440-019-00049-2

Sample: gastric tissue
BIOMEDICINE & PHARMACOTHERAPY (2017) IF: 2.759
Anti-steatotic and anti-inflammatory effects of Hovenia dulcis Thunb. extracts in chronic alcohol-fed rats

DOI: 10.1016/j.biopha.2017.03.077

Sample: Serum
JOURNAL OF BIOMEDICAL SCIENCE (2015) IF: 2.763
High fat diet-induced inflammation and oxidative stress are attenuated by N-acetylneuraminic acid in rats

DOI: 10.1186/s12929-015-0211-6

Sample: Serum
ANDROLOGIA (2021) IF: 2.775
Decrease in reproductive dysfunction using aflatoxin B1 exposure: a treatment with 3-indolepropionic acid in albino Wistar rat

DOI: 10.1111/and.14248

PMID: 34541692
Sample: testicular,epididymal,hypothalamic
ANDROLOGIA (2021) IF: 2.775
Cysteamine mitigates torsion/detorsion-induced reperfusion injury via inhibition of apoptosis, oxidative stress and inflammatory responses in experimental rat model

DOI: 10.1111/and.14243

PMID: 34498746
Sample: serum
ANDROLOGIA (2021) IF: 2.775
Achillea millefolium alleviates testicular damage in paclitaxel-intoxicated rats via attenuation of testicular oxido-inflammatory stress and apoptotic responses

DOI: 10.1111/and.14028

PMID: 33650701
Sample: Tissue homogenate(testicular)
JOURNAL OF MEDICINAL FOOD (2021) IF: 2.786
Zingerone Administered Neonatally Prevents the Subsequent Development of High Dietary Fructose-Induced Fatty Liver in Sprague Dawley Rats

DOI: 10.1089/jmf.2020.0189

PMID: 33512269
Sample: plasma
ANAEROBE (2022) IF: 2.837
The comparison of changes in fecal and mucosal microbiome in metabolic endotoxemia induced by a high-fat diet

DOI: 10.1016/j.anaerobe.2022.102615

PMID: 35850456
Sample: serum,colon
Diabetes Metabolic Syndrome and Obesity-Targets and Therapy (2020) IF: 2.842
Kukoamine B Ameliorate Insulin Resistance, Oxidative Stress, Inflammation and Other Metabolic Abnormalities in High-Fat/High-Fructose-Fed Rats

DOI: 10.2147/DMSO.S247844

Sample: serum
Diabetes Metabolic Syndrome and Obesity-Targets and Therapy (2020) IF: 2.842
Activation of Nrf2 Signaling by Apelin Attenuates Renal Ischemia Reperfusion Injury in Diabetic Rats

DOI: 10.2147/DMSO.S246743

PMID: 32606875
Sample: Serum
WOUND REPAIR AND REGENERATION (2019) IF: 2.85
Effects of depression on healing and inflammatory responses of acute wounds in rats

DOI: 10.1111/wrr.12726

Sample: serum
Toxin Reviews (2020) IF: 2.851
Nicotine lowers TNF-α, IL-1b secretion and leukocyte accumulation via nAChR in rat stomach

DOI: 10.1080/15569543.2020.1790604

Sample: Tissue homogenate
ACS Omega (2020) IF: 2.87
Antiarthritic Potential of Comprehensively Standardized Extract of Alternanthera bettzickiana: In Vitro and In Vivo Studies

DOI: 10.1021/acsomega.0c01670

PMID: 32803042
Sample: Serum
SAUDI PHARMACEUTICAL JOURNAL (2020) IF: 2.879
Possible combined effect of perindopril and Azilsartan in an experimental model of dementia in rats

DOI: 10.1016/j.jsps.2020.03.009

Sample: Tissue homogenate
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY (2019) IF: 2.895
Rutin abrogates manganese—Induced striatal and hippocampal toxicity via inhibition of iron depletion, oxidative stress, inflammation and suppressing the NF-κB signaling pathway

DOI: 10.1016/j.jtemb.2019.01.014

Sample: Tissue homogenate
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2021) IF: 2.9
Phenolics-Enriched Fraction of Pterospermum Lanceifolium Roxb. efficiently Reverses the Hepatocellular Carcinoma in NDEA-Induced HCC Rats

DOI: 10.1080/01635581.2021.1922716

PMID: 34018459
Sample: Tissue homogenate
HUMAN & EXPERIMENTAL TOXICOLOGY (2021) IF: 2.903
Luteolin attenuates doxorubicin-induced derangements of liver and kidney by reducing oxidative and inflammatory stress to suppress apoptosis:

DOI: 10.1177/09603271211006171

Sample: Tissue homogenate
HUMAN & EXPERIMENTAL TOXICOLOGY (2022) IF: 2.903
Idebenone regulates sirt1/Nrf2/TNF-α pathway with inhibition of oxidative stress, inflammation, and apoptosis in testicular torsion/detorsion in juvenile rats:

DOI: 10.1177/09603271221102515

Sample: serum
HUMAN & EXPERIMENTAL TOXICOLOGY (2021) IF: 2.903
Biochemical assessment of the neurotoxicity of gold nanoparticles functionalized with colorectal cancer-targeting peptides in a rat model:

DOI: 10.1177/09603271211017611

Sample: Tissue homogenate(brain)
PROSTAGLANDINS & OTHER LIPID MEDIATORS (2016) IF: 2.905
Participation of oleic acid in the formation of the aortic aneurysm in Marfan syndrome patients

DOI: 10.1016/j.prostaglandins.2016.05.001

Sample: Tissue homogenate
Future Microbiology (2020) IF: 2.907
The anti-inflammatory, anti-oxidant and protective effects of a probiotic mixture on organ toxicity in a rat model

DOI: 10.2217/fmb-2020-0005

PMID: 32250184
Sample: Serum
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2019) IF: 2.928
Green tea polyphenols attenuate hepatic steatosis, and reduce insulin resistance and inflammation in high-fat diet-induced rats

DOI: 10.3892/ijmm.2019.4285

Sample: serum
DIGESTIVE DISEASES AND SCIENCES (2019) IF: 2.937
Apocynin Attenuates Acute Kidney Injury and Inflammation in Rats with Acute Hypertriglyceridemic Pancreatitis

DOI: 10.1007/s10620-019-05892-0

PMID: 31617131
Sample: Serum
INFLAMMATION (2019) IF: 2.939
Protective Effects of Tyrosol Against DSS-Induced Ulcerative Colitis in Rats

DOI: 10.1007/s10753-019-01028-8

Sample: colon tissue
INFLAMMATION (2019) IF: 2.939
Nobiletin Protects from Renal Ischemia-Reperfusion Injury in Rats by Suppressing Inflammatory Cytokines and Regulating iNOS-eNOS Expressions

DOI: 10.1007/s10753-019-01123-w

PMID: 31705353
Sample: Serum
WOUND REPAIR AND REGENERATION (2018) IF: 2.952
Therapeutic efficacy of early photobiomodulation therapy on the zones of stasis in burns: An experimental rat model study

DOI: 10.1111/wrr.12661

PMID: 30118166
Sample: Tissue homogenate
Molecular Medicine Reports (2018) IF: 2.952
Puerarin reduces ischemia/reperfusion-induced myocardial injury in diabetic rats via upregulation of vascular endothelial growth factor A/angiotensin-1 and suppression of apoptosis

DOI: 10.3892/mmr.2018.8754

Sample: plasma
Molecular Medicine Reports (2020) IF: 2.952
Placenta‑derived mesenchymal stem cells ameliorate lipopolysaccharide‑induced inflammation in RAW264.7 cells and acute lung injury in rats

DOI: 10.3892/mmr.2020.11231

Sample: Cell culture supernatant
Molecular Medicine Reports (2021) IF: 2.952
NF‑κB is negatively associated with Nurr1 to reduce the inflammatory response in Parkinson's disease

DOI: 10.3892/mmr.2021.12035

PMID: 33864663
Sample: Cell
JOURNAL OF CELLULAR BIOCHEMISTRY (2018) IF: 2.959
MAPKs and NF‐κB‐mediated acrylamide‐induced neuropathy in rat striatum and human neuroblastoma cells SY5Y

DOI: 10.1002/jcb.27671

Sample: Tissue homogenate
JOURNAL OF CELLULAR BIOCHEMISTRY (2018) IF: 2.959
Exosomes derived from miR‐146a‐modified adipose‐derived stem cells attenuate acute myocardial infarction−induced myocardial damage via downregulation of early growth response factor 1

DOI: 10.1002/jcb.27731

Sample: Serum,Cell culture supernatant
BIOLOGY OF REPRODUCTION (2019) IF: 2.96
Changes in alpha-7 nicotinic acetylcholine receptor and macrophage polarization state participate in the regulation of cervical remodeling in pregnant rats

DOI: 10.1093/biolre/ioz133

Sample: Tissue homogenate
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2019) IF: 2.965
Protective effect of betulinic acid on Freund's complete adjuvant‐induced arthritis in rats

DOI: 10.1002/jbt.22373

Sample: serum,synovium
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2019) IF: 2.965
Nobiletin attenuates acetaminophen‐induced hepatorenal toxicity in rats

DOI: 10.1002/jbt.22427

Sample: Serum,Tissue homogenate
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2019) IF: 2.965
Fluoride and diethylnitrosamine coexposure enhances oxido‐inflammatory responses and caspase‐3 activation in liver and kidney of adult rats

DOI: 10.1002/jbt.22327

Sample: Serum
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2020) IF: 2.967
The gut microbiota attenuates muscle wasting by regulating energy metabolism in chemotherapy-induced malnutrition rats

DOI: 10.1007/s00280-020-04060-w

PMID: 32415349
Sample: Serum,Tissue homogenate,Feces
Journal of Ovarian Research (2020) IF: 2.989
The effect of glutamine on Dehydroepiandrosterone-induced polycystic ovary syndrome rats.

DOI: 10.1186/s13048-020-00650-7

Sample: Serum
Cardiovascular Toxicology (2018) IF: 2.989
Catechin Attenuates Coronary Heart Disease in a Rat Model by Inhibiting Inflammation

DOI: 10.1007/s12012-018-9449-z

Sample: Serum
Veterinary Research Forum (2019) IF: 1.054
Crocin exerts improving effects on indomethacin-induced small intestinal ulcer by antioxidant, anti-inflammatory and anti-apoptotic mechanisms

DOI: 10.30466/vrf.2018.93512.2256

Sample: Small intestine tissue
Asian Pacific Journal of Tropical Medicine (2015) IF: 1.062
Influence of simvastatin on dopaminergic neurons of lipopolysaccharide–induced rat model of Parkinson's disease

DOI: 10.1016/S1995-7645(14)60189-9

Sample: Tissue homogenate
SCANDINAVIAN CARDIOVASCULAR JOURNAL (2020) IF: 1.084
St. Thomas and del Nido cardioplegia are superior to Custodiol cardioplegia in a rat model of donor heart

DOI: 10.1080/14017431.2020.1846772

PMID: 33185130
Sample: Tissue homogenate
JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH (2017) IF: 1.099
Fetal liver injury ameliorated by migration inhibitory factor inhibition in a rat model of acute pancreatitis in pregnancy

DOI: 10.1111/jog.13538

Sample: serum
Annals of Surgical Treatment and Research (2019) IF: 1.181
Examination of protective and therapeutic effects of ruscogenin on cerulein-induced experimental acute pancreatitis in rats

DOI: 10.4174/astr.2019.97.6.271

PMID: 31824881
Sample: Serum,Tissue homogenate
CHEMICAL & PHARMACEUTICAL BULLETIN (2018) IF: 1.258
Anti-inflammatory Effects of a Small Molecule Gastrin-Releasing Peptide Receptor Antagonist on Adjuvant-Induced Rheumatoid Arthritis in rats

DOI: 10.1248/cpb.c17-00887

Sample: serum
Experimental and Therapeutic Medicine (2017) IF: 1.261
Tocotrienol alleviates inflammation and oxidative stress in a rat model of spinal cord injury via suppression of transforming growth factor-β

DOI: 10.3892/etm.2017.4505

Sample: Serum
Experimental and Therapeutic Medicine (2017) IF: 1.261
Astragalus polysaccharides combined with ibuprofen exhibit a therapeutic effect on septic rats via an anti‑inflammatory cholinergic pathway

DOI: 10.3892/etm.2017.4865

Sample: Plasma
Brazilian Journal of Cardiovascular Surgery (2021) IF: 1.312
Probiotic Saccharomyces boulardii Alleviates Lung Injury by Reduction of Oxidative Stress and Cytokine Response Induced by Supraceliac Aortic Ischemia-Reperfusion Injury in Rats

DOI: 10.21470/1678-9741-2020-0153

Sample: serum,Lung tissue
CONTRIBUTIONS TO PLASMA PHYSICS (2018) IF: 1.318
Effects and mechanisms of cold atmospheric plasma on skin wound healing of rats

DOI: 10.1002/ctpp.201800025

Sample: skin tissues
Journal of Burn Care & Research (2017) IF: 1.349
Mitochondrial DNA-Induced Inflammatory Responses and Lung Injury in Thermal Injury Rat ModelProtective Effect of Epigallocatechin Gallate

DOI: 10.1097/BCR.0000000000000501

Sample: serum
JOURNAL OF FOOD BIOCHEMISTRY (2019) IF: 1.358
Epicatechin and scopoletin rich Morinda citrifolia (Noni) leaf extract supplementation, mitigated Osteoarthritis via anti‐inflammatory, anti‐oxidative, and anti‐protease pathways

DOI: 10.1111/jfbc.12755

Sample: Serum
MOLECULAR BIOLOGY REPORTS (2020) IF: 1.402
Acacetin improves endothelial dysfunction and aortic fibrosis in insulin-resistant SHR rats by estrogen receptors

DOI: 10.1007/s11033-020-05746-3

PMID: 32892299
Sample: Serum
Experimental and Therapeutic Medicine (2018) IF: 1.41
Protective effect of dexpanthenol against cisplatin‑induced hepatotoxicity

DOI: 10.3892/etm.2018.6683

Sample: Tissue homogenate
Experimental and Therapeutic Medicine (2018) IF: 1.41
Gambogic acid exerts cardioprotective effects in a rat model of acute myocardial infarction through inhibition of inflammation, iNOS and NF‑κB/p38 pathway

DOI: 10.3892/etm.2017.5599

Sample: Serum
ARQUIVOS DE NEURO-PSIQUIATRIA (2022) IF: 1.42
Endogenous and exogenous serotonin, but not sumatriptan, ameliorate seizures and neuroinflammation in the pentylenetetrazole-induced seizure model in rats

DOI: 10.1590/0004-282X-ANP-2021-0101

PMID: 35239805
Sample: brain tissue,serum
PATHOLOGY RESEARCH AND PRACTICE (2018) IF: 1.466
miR-93-3p alleviates lipopolysaccharide-induced inflammation and apoptosis in H9c2 cardiomyocytes by inhibiting toll-like receptor 4

DOI: 10.1016/j.prp.2018.08.024

PMID: 30195636
Sample: Cell culture supernatant
Molecular Medicine Reports (2014) IF: 1.484
Isoproterenol‑mediated heme oxygenase‑1 induction inhibits high mobility group box 1 protein release and protects against rat myocardial ischemia/reperfusion injury in vivo

DOI: 10.3892/mmr.2014.2026

Sample: myocardial tissues
Natural Product Communications (2023) IF: 1.496
Vanillic Acid Alleviates Right Ventricular Function in Rats With MCT-Induced Pulmonary Arterial Hypertension

DOI: 10.1177/1934578X221148896

Sample: serum
Iranian Journal of Basic Medical Sciences (2018) IF: 1.514
The protective effects of naringin against 5-fluorouracil-induced hepatotoxicity and nephrotoxicity in rats

DOI: 10.22038/IJBMS.2018.27510.6714

Sample: Serum
PEDIATRICS INTERNATIONAL (2021) IF: 1.524
Early administration of milrinone ameliorates lung and kidney injury during sepsis in juvenile rats

DOI: 10.1111/ped.14917

PMID: 34242458
Sample: Lung，kidney
ORL-Journal for Oto-Rhino-Laryngology Head and Neck Surgery (2022) IF: 1.538
Mucolytic and Antioxidant Effects of Intranasal Acetylcysteine Use on Acute Rhinosinusitis in Rats with an Acute Rhinosinusitis Model

DOI: 10.1159/000524869

PMID: 35661091
Sample: nose,sinuses
PATHOLOGY RESEARCH AND PRACTICE (2017) IF: 1.543
A preliminary study on fetal lung injury in a rat model of acute pancreatitis in pregnancy

DOI: 10.1016/j.prp.2017.09.016

Sample: serum
Molecular Medicine Reports (2015) IF: 1.554
Asiaticoside attenuates the effects of spinal cord injury through antioxidant and anti‑inflammatory effects, and inhibition of the p38‑MAPK mechanism

DOI: 10.3892/mmr.2015.4425

Sample: Serum
Molecular Medicine Reports (2016) IF: 1.559
Protective effect of paeoniflorin on inflammation and apoptosis in the cerebral cortex of a transgenic mouse model of Alzheimer's disease

DOI: 10.3892/mmr.2016.4805

Sample: cerebral cortex
Asian Journal of Surgery (2019) IF: 1.56
Potent therapeutic effects of ruscogenin on gastric ulcer established by acetic acid

DOI: 10.1016/j.asjsur.2019.07.001

PMID: 31345657
Sample: Tissue homogenate
MEDICAL SCIENCE MONITOR (2017) IF: 1.585
Epigallocatechin Gallate Attenuates Hip Fracture-Induced Acute Lung Injury by Limiting Mitochondrial DNA (mtDNA) Release

DOI: 10.12659/MSM.902477

Sample: Bronchoalveolar Lavage Fluid
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY (2016) IF: 1.617
Anti-oxidant and anti-inflammatory effects of apigenin in a rat model of sepsis: an immunological, biochemical, and histopathological study

DOI: 10.3109/08923973.2016.1173058

Sample: Serum
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL (2016) IF: 1.621
LncRNA NONRATT021972 siRNA rescued decreased heart rate variability in diabetic rats in superior cervical ganglia

DOI: 10.1016/j.autneu.2016.07.012

Sample: serum
Journal of Oleo Science (2022) IF: 1.628
Chemoprotective Effect of Decalactone on Hepatic Cancer via Diminishing the Inflammatory Response and Oxidative Stress

DOI: 10.5650/jos.ess22033

PMID: 35965085
Sample: liver
BIOLOGIA (2022) IF: 1.653
The effects of β-escin on inflammation, oxidative stress and Langerhans islet cells in high-fat diet and streptozotocin injection induced experimental type-2 diabetes model

DOI: 10.1007/s11756-022-01266-6

Sample: serum
JOURNAL OF FOOD BIOCHEMISTRY (2020) IF: 1.662
The effects of chrysin on lipopolysaccharide‐induced sepsis in rats

DOI: 10.1111/jfbc.13359

Sample: lung,liver,kidney
JOURNAL OF FOOD BIOCHEMISTRY (2020) IF: 1.662
Citrus hystrix leaf extract attenuated diabetic‐cataract in STZ‐rats

DOI: 10.1111/jfbc.13258

Sample: serum
RENAL FAILURE (2019) IF: 1.687
The aqueous extract of aged black garlic ameliorates colistin-induced acute kidney injury in rats

DOI: 10.1080/0886022X.2018.1561375

PMID: 30714460
Sample: Tissue homogenate
Molecular Medicine Reports (2017) IF: 1.692
Protective effect of diethylcarbamazine inhibits NF-κB activation in isoproterenol-induced acute myocardial infarction rat model through the PARP pathway

DOI: 10.3892/mmr.2017.6695

Sample: Serum
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2018) IF: 1.694
Qiliqiangxin Protects against Renal Injury in Rat with Cardiorenal Syndrome Type I through Regulating the Inflammatory and Oxidative Stress Signaling

DOI: 10.1248/bpb.b17-00930

PMID: 30068867
Sample: Plasma
Molecular & Cellular Toxicology (2022) IF: 1.718
Efficacy of urinary trypsin inhibitor in the treatment of rats with severe sepsis and its effects on coagulation and immunity

DOI: 10.1007/s13273-022-00303-4

Sample: hippocampus
BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT (2022) IF: 1.762
Nelumbo nucifera Gaertn. leaves: network pharmacology and molecular docking analysis of active ingredients and their mechanisms of action in treating atherosclerosis

DOI: 10.1080/13102818.2022.2116996

Sample: serum
European Journal of Trauma and Emergency Surgery (2019) IF: 1.781
Beneficial effects of bardoxolone methyl, an Nrf2 activator, on crush-related acute kidney injury in rats

DOI: 10.1007/s00068-019-01216-z

PMID: 31471671
Sample: Tissue homogenate
MICROBIAL PATHOGENESIS (2015) IF: 1.794
Candida glabrata induced infection of rat tracheal epithelial cells is mediated by TLR-2 induced activation of NF-κB

DOI: 10.1016/j.micpath.2015.10.009

Sample: Cell lysate
Food Science & Nutrition (2020) IF: 1.797
Protective effect of Alpinetin on rats with chronic obstructive pulmonary disease

DOI: 10.1002/fsn3.1952

PMID: 33312544
Sample: Cell culture supernatant
BURNS (2014) IF: 1.836
Effect and possible mechanism of monocyte-derived VEGF on monocyte–endothelial cellular adhesion after electrical burns

DOI: 10.1016/j.burns.2014.10.030

Sample: Serum,Cell culture supernatant
ANDROLOGIA (2019) IF: 1.84
Sitagliptin protects male albino rats with testicular ischaemia/reperfusion damage: Modulation of VCAM‐1 and VEGF‐A

DOI: 10.1111/and.13472

Sample: Serum
INTERNATIONAL UROLOGY AND NEPHROLOGY (2020) IF: 1.843
Vinpocetine reduces cisplatin-induced acute kidney injury through inhibition of NF–κB pathway and activation of Nrf2/ARE pathway in rats

DOI: 10.1007/s11255-020-02485-z

Sample: Serum,Urine,Tissue homogenate
Molecular Medicine Reports (2019) IF: 1.851
MicroRNA‑22 alleviates inflammation in ischemic stroke via p38 MAPK pathways

DOI: 10.3892/mmr.2019.10269

Sample: serum
Annals of Surgical Treatment and Research (2022) IF: 1.859
Comparison of the healing effects of mesazaline and Ganoderma lucidum in acetic acid-induced colitis in rats

DOI: 10.4174/astr.2022.102.1.29

PMID: 35071117
Sample: colonic tissue
Journal of Zhejiang University-SCIENCE B (2019) IF: 1.879
Improvement in post-partum uterine involution in rats treated with Apios americana

DOI: 10.1631/jzus.B1800475

Sample: serum
MEDICAL SCIENCE MONITOR (2020) IF: 1.918
Carbon Monoxide Inhibits the Expression of Proteins Associated with Intestinal Mucosal Pyroptosis in a Rat Model of Sepsis Induced by Cecal Ligation and Puncture

DOI: 10.12659/MSM.920668

Sample: serum,intestinal tissue
Molecular Medicine Reports (2018) IF: 1.922
Sparstolonin B attenuates spinal cord injury‑induced inflammation in rats by modulating TLR4‑trafficking

DOI: 10.3892/mmr.2018.8561

Sample: spinal cord
Molecular Medicine Reports (2018) IF: 1.922
Neuroprotective effect of tanshinone IIA weakens spastic cerebral palsy through inflammation, p38MAPK and VEGF in neonatal rats

DOI: 10.3892/mmr.2017.8069

Sample: hippocampus
EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES (2019) IF: 1.927
Hyperuricemia Inhibition Protects SD Rats Against Fructose-Induced Obesity Hypertension Via Modulation of Inflammation and Renin-Angiotensin System in Adipose Tissue

DOI: 10.1055/a-1023-6710

PMID: 31683330
Sample: Serum
International Journal of Endocrinology (2015) IF: 1.948
17β Estradiol Modulates Perfusion Pressure and Expression of 5-LOX and CYP450 4A in the Isolated Kidney of Metabolic Syndrome Female Rats

DOI: 10.1155/2015/149408

Sample: Tissue homogenate
ANDROLOGIA (2020) IF: 1.951
Carob attenuates nicotine-induced oxidative stress and intratesticular damage in male rats

DOI: 10.1111/and.13670

Sample: serum
Current Research in Toxicology (2022)
Zn and Se abrogate heavy metal mixture induced ovarian and thyroid oxido-inflammatory effects mediated by activation of NRF2-HMOX-1 in female albino rats

DOI: 10.1016/j.crtox.2022.100098

Sample: ovarian,thyroid,thyroid cell
International Journal of Fertility & Sterility (2022)
Silver Nanoparticles Biofabricated from Cinnamomum zeylanicum Reduce IL-6, IL-18, and TNF-ɑ in Female Rats with Polycystic Ovarian Syndrome

DOI: 10.22074/IJFS.2022.539396.1189

Sample: serum
Journal of Diabetes and Metabolic Disorders (2022)
Protective effects of Labisia pumila against neuropathy in a diabetic rat model

DOI: 10.1007/s40200-021-00905-0

Sample: serum
Journal of Diabetes and Metabolic Disorders (2020)
Polyphenolic-rich extracts of Andrographis paniculata mitigate hyperglycemia via attenuating β-cell dysfunction, pro-inflammatory cytokines and oxidative stress in alloxan-induced diabetic Wistar albino rat

DOI: 10.1007/s40200-020-00690-2

Sample: serum
Journal of Diabetes and Metabolic Disorders (2022)
Mineralocorticoid receptor blockade attenuates hyperandrogenic metabolic dysregulation in letrozole-induced PCOS rat model

DOI: 10.1007/s40200-022-01097-x

PMID: 36404823
Sample: plasma,ovarian
Toxicology Reports (2019)
Manganese suppresses oxidative stress, inflammation and caspase-3 activation in rats exposed to chlorpyrifos

DOI: 10.1016/j.toxrep.2019.02.007

PMID: 30859069
Sample: Tissue homogenate
Turkish Journal of Pharmaceutical Sciences (2021)
Investigation of the Genotoxic, Cytotoxic, Apoptotic, and Oxidant Effects of Olive Leaf Extracts on Liver Cancer Cell Lines

DOI: 10.4274/tjps.galenos.2021.03271

Sample: H4IIE cell,clone-9 cell
Toxicology Reports (2023)
Interactions of alcohol and combination antiretroviral (cART) drug in diabetic male Sprague Dawley rats: Hippocampal perturbations and toxicosis

DOI: 10.1016/j.toxrep.2023.01.009

Sample: brain
Physiological Reports (2021)
Inflammation-induced left ventricular fibrosis is partially mediated by tumor necrosis factor-α

DOI: 10.14814/phy2.15062

Sample: serum
IBRO Neuroscience Reports (2022)
Highly active antiretroviral therapy-silver nanoparticle conjugate interacts with neuronal and glial cells and alleviates anxiety-like behaviour in streptozotocin-induced diabetic rats

DOI: 10.1016/j.ibneur.2022.06.003

PMID: 35769902
Sample: brain
Brazilian Journal of Anesthesiology (2021)
Dose-related effects of dexmedetomidine on sepsis-initiated lung injury in rats

DOI: 10.1016/j.bjane.2021.02.051

Sample: plasma
IBRO Reports (2019)
Combination antiretroviral therapy (cART)-induced hippocampal disorders: Highlights on therapeutic potential of Naringenin and Quercetin

DOI: 10.1016/j.ibror.2019.04.002

Sample: hippocampus tissues
Advances in Traditional Medicine (2020)
Anti-inflammatory activity of Xanthium indicum on carrageenan-induced paw edema in rats

DOI: 10.1007/s13596-020-00502-1

Sample: Tissue homogenate
Advances in Traditional Medicine (2023)
Amaranthus spinosus (Spiny Pigweed) methanol leaf extract alleviates oxidative and inflammation induced by doxorubicin in male sprague dawley rats

DOI: 10.1007/s13596-022-00677-9

Sample: serum
Scientific African (2022)
Allium vineale methanol extract attenuated oxidative stress and inflammation induced by doxorubicin in Sprague Dawley Rats

DOI: 10.1016/j.sciaf.2022.e01244

Sample: serum
Journal of Diabetes and Metabolic Disorders (2021)
Acetate supplementation restores testicular function by modulating Nrf2/PPAR-γ in high fat diet-induced obesity in Wistar rats

DOI: 10.1007/s40200-021-00924-x

Sample: testicular tissue
International Journal of Clinical and Experimental Pathology (2020) IF: 0.252
Sepsis causes heart injury through endoplasmic reticulum stress-mediated apoptosis signaling pathway

PMID: 32509067
Sample: serum
TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH (2020) IF: 0.504
Effect of penehyclidine hydrochloride on IL-6, TNF-α, HIF- 1α and oxidative stress in lung tissue of young rats with acute lung injury

DOI: 10.4314/tjpr.v19i7.14

Sample: Serum
INTERNATIONAL SURGERY (2018) IF: 0.576
Protective Effect of Nigella Sativa in an Animal Model of Colon Anastomosis With Ischemia/Reperfusion Injury

DOI: 10.9738/INTSURG-D-15-00301.1

Sample: colon tissue
Acta Cirurgica Brasileira (2016) IF: 0.58
Toll-like receptor 7 involves the injury in acute kidney ischemia/reperfusion of STZ-induced diabetic rats

DOI: 10.1590/S0102-865020160070000004

Sample: Serum
Acta Cirurgica Brasileira (2017) IF: 0.729
Dexmedetomidine protects against renal ischemia and reperfusion injury by inhibiting the P38-MAPK/TXNIP signaling activation in streptozotocin induced diabetic rats

DOI: 10.1590/s0102-865020170060000003

Sample: Serum,Plasma
GENETICS AND MOLECULAR RESEARCH (2015) IF: 0.775
Protective effect of penehyclidine hydrochloride on lipopolysaccharide-induced acute kidney injury in rat.

DOI: 10.4238/2015.August.10.14

Sample: serum
Biologia Futura (2022) IF: 0.821
The effects of bee venom on liver and skeletal muscle in exhaustive swimming rats

DOI: 10.1007/s42977-022-00115-6

Sample: Serum
RENAL FAILURE (2016) IF: 0.875
Effect of apelin hormone on renal ischemia/reperfusion induced oxidative damage in rats

DOI: 10.1080/0886022X.2016.1184957

Sample: Serum
INDIAN JOURNAL OF PHARMACOLOGY (2020) IF: 0.888
Mangiferin ameliorates intracerebroventricular-quinolinic acid-induced cognitive deficits, oxidative stress, and neuroinflammation in Wistar rats

DOI: 10.4103/ijp.IJP_699_19

Sample: Tissue homogenate
Ulusal Travma ve Acil Cerrahi Dergisi-Turkish Journal of Trauma & Emergency Surgery (2022) IF: 0.894
Intraductal botulinum toxin injection suppressed the inflammation in experimental acute pancreatitis.

DOI: 10.14744/tjtes.2021.90140

Sample: Serum
Acta Cirurgica Brasileira (2019) IF: 0.931
Effect of sevoflurane pretreatment in relieving liver ischemia/reperfusion-induced pulmonary and hepatic injury

DOI: 10.1590/s0102-865020190080000005

PMID: 31618405
Sample: Serum
Turkish Journal Of Medical Sciences (2021) IF: 0.973
Antiinflammatory effects of adalimumab, tocilizumab, and steroid on lipopolysaccharide-induced lung injury

DOI: 10.3906/sag-2010-303

Sample: bronchoalveolar lavage (BAL)
Acta Cirurgica Brasileira (2020) IF: 0.974
TNF-alpha inhibitor adalimumab attenuates endotoxin induced cardiac damage in rats

DOI: 10.1590/s0102-865020200020000002

Sample: Serum

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DOI: 10.1186/s13054-022-04184-w
PMID: 36258235	Sample: bronchoalveolar lavages (BAL)

DOI: 10.1016/j.biomaterials.2021.120952
PMID: 34147720	Sample: heart

DOI: 10.1002/adhm.202201661
PMID: 36189833	Sample: BMSCs

DOI: 10.1002/adhm.202201680
PMID: 36049781	Sample: Uterine

DOI: 10.1186/s12951-022-01277-0
PMID: 35123501	Sample: rat bone marrow mesenchymal stem cells (rBMSCs)

DOI: 10.1021/acsami.1c03589
PMID: 33764751	Sample: Plasma

DOI: 10.1007/s00018-016-2426-4
	Sample: Cell culture supernatant

DOI: 10.1016/j.ijbiomac.2022.08.161
PMID: 36037912	Sample: serum

DOI: 10.1186/s13287-022-03000-0
PMID: 35841081	Sample: serum

DOI: 10.1111/ajt.17032
PMID: 35303398	Sample: serum

DOI: 10.1016/j.apmt.2022.101571
	Sample: Serum

DOI: 10.1021/acs.chemmater.2c01300
	Sample: blood

DOI: 10.1186/s12974-023-02715-y
	Sample: brain,serum

DOI: 10.1186/s12974-021-02303-y
PMID: 34736493	Sample: brain

DOI: 10.1186/s12974-020-01891-5
PMID: 32665021	Sample: Tissue homogenate

DOI: 10.1186/s12974-021-02255-3
PMID: 34530836	Sample: brain

DOI: 10.1111/cns.13906
PMID: 35789066	Sample: blood

DOI: 10.1155/2022/3576892
PMID: 35855864	Sample: serum

DOI: 10.1016/j.biopha.2022.113418
PMID: 36076540	Sample: C6 glioma xenogfrat tissue

DOI: 10.3390/cells11182771
PMID: 36139346	Sample: brain tissue

DOI: 10.3390/antiox11112154
PMID: 36358526	Sample: brain tissue

DOI: 10.1016/j.fct.2021.112550
PMID: 34517076	Sample: astrocyte

DOI: 10.3389/fcvm.2021.654969
PMID: 34485393	Sample: H9c2 cell

DOI: 10.3389/fcimb.2022.876781
PMID: 36061858	Sample: jejunum tissue,medulla oblongata tissue

Rat TNF-α(Tumor Necrosis Factor Alpha) ELISA Kit

To Purchase E-EL-R2856

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Kit components & Storage

Technical Data

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Recovery

Linearity

Target Information

Assay Procedures

Citations

CRITICAL CARE (2022) IF: 19.334

BIOMATERIALS (2021) IF: 12.479

Advanced Healthcare Materials (2022) IF: 11.092

Advanced Healthcare Materials (2022) IF: 11.092

Applied Materials Today (2022) IF: 10.041

JOURNAL OF NANOBIOTECHNOLOGY (2022) IF: 10.435

CHEMISTRY OF MATERIALS (2022) IF: 10.508

ACS Applied Materials & Interfaces (2021) IF: 9.2289

CELLULAR AND MOLECULAR LIFE SCIENCES (2016) IF: 9.2609

Journal of Neuroinflammation (2023) IF: 9.587

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022) IF: 8.025

Stem Cell Research & Therapy (2022) IF: 8.0790

AMERICAN JOURNAL OF TRANSPLANTATION (2022) IF: 8.086

Journal of Neuroinflammation (2021) IF: 8.3219

Journal of Neuroinflammation (2020) IF: 8.3219

Journal of Neuroinflammation (2021) IF: 8.3219

BRITISH JOURNAL OF PHARMACOLOGY (2022) IF: 8.74

International Journal of Nanomedicine (2023) IF: 7.033

CNS Neuroscience & Therapeutics (2022) IF: 7.035

Oxidative Medicine and Cellular Longevity (2023) IF: 7.31

Oxidative Medicine and Cellular Longevity (2022) IF: 7.31

BIOMEDICINE & PHARMACOTHERAPY (2022) IF: 7.419

BIOMEDICINE & PHARMACOTHERAPY (2023) IF: 7.419

Cells (2022) IF: 7.666

Antioxidants (2022) IF: 7.675

Antioxidants (2022) IF: 7.675

FOOD AND CHEMICAL TOXICOLOGY (2021) IF: 6.025

Frontiers in Cardiovascular Medicine (2021) IF: 6.05

Frontiers in Cellular and Infection Microbiology (2022) IF: 6.073

Frontiers in Cellular and Infection Microbiology (2022) IF: 6.073

Frontiers in Cell and Developmental Biology (2022) IF: 6.081

American Journal of Cancer Research (2021) IF: 6.166

BRAIN BEHAVIOR AND IMMUNITY (2019) IF: 6.17

MOLECULAR NEUROBIOLOGY (2017) IF: 6.19

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022) IF: 6.208

Arabian Journal of Chemistry (2022) IF: 6.212

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2019) IF: 6.291

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2021) IF: 6.291

Antioxidants (2022) IF: 6.313

Pharmaceutics (2022) IF: 6.321

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2023) IF: 6.51

Pharmaceutics (2023) IF: 6.525

BIOMEDICINE & PHARMACOTHERAPY (2021) IF: 6.53

BIOMEDICINE & PHARMACOTHERAPY (2018) IF: 6.53

BIOMEDICINE & PHARMACOTHERAPY (2020) IF: 6.53

BIOMEDICINE & PHARMACOTHERAPY (2021) IF: 6.53

BIOMEDICINE & PHARMACOTHERAPY (2021) IF: 6.53

BIOMEDICINE & PHARMACOTHERAPY (2021) IF: 6.53

BIOMEDICINE & PHARMACOTHERAPY (2021) IF: 6.53

BIOMEDICINE & PHARMACOTHERAPY (2021) IF: 6.53

BIOMEDICINE & PHARMACOTHERAPY (2022) IF: 6.53

BIOMEDICINE & PHARMACOTHERAPY (2022) IF: 6.53

BIOMEDICINE & PHARMACOTHERAPY (2020) IF: 6.53

BIOMEDICINE & PHARMACOTHERAPY (2022) IF: 6.53

Oxidative Medicine and Cellular Longevity (2022) IF: 6.543

Oxidative Medicine and Cellular Longevity (2021) IF: 6.543

Oxidative Medicine and Cellular Longevity (2022) IF: 6.543

Frontiers in Nutrition (2022) IF: 6.576

Cells (2019) IF: 6.6

PHYTOMEDICINE (2022) IF: 6.656

PHYTOMEDICINE (2022) IF: 6.656

Frontiers in Cell and Developmental Biology (2021) IF: 6.684

Nutrients (2022) IF: 6.706

Nutrients (2022) IF: 6.706

Nutrients (2022) IF: 6.706

LIFE SCIENCES (2022) IF: 6.78

LIFE SCIENCES (2022) IF: 6.78

DOI: 10.3389/fcimb.2022.945851
PMID: 36061856	Sample: serum

DOI: 10.3389/fcell.2022.1003767
PMID: 36313556	Sample: lung tissue


PMID: 33575076	Sample: Tissue homogenate(liver tissue),Serum

DOI: 10.1016/j.bbi.2019.08.007
	Sample: plasma，brain

DOI: 10.1007/s12035-017-0636-x
	Sample: Tissue homogenate

DOI: 10.1016/j.ecoenv.2019.110065
PMID: 31869719	Sample: Tissue homogenate

DOI: 10.1016/j.ecoenv.2021.112501
PMID: 34265528	Sample: serum

DOI: 10.3390/antiox11050863
PMID: 35624727	Sample: testicular tissue

DOI: 10.3390/pharmaceutics14051108
PMID: 35631694	Sample: LX-2 cell

DOI: 10.1016/j.biopha.2020.111184
PMID: 33418305	Sample: Plasma