A2M Monoclonal Antibody

  • monoclonal antibody-Elabscience
  • monoclonal antibody-Elabscience
  • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
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    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience

      Catalog number:E-AB-27021

      Synonyms:A2m,A2MG,Alpha 2 M,Alpha 2M,Alpha-2-M,Alpha-2-macroglobulin,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5,CPAMD5,DKFZp779B086,FWP007,S863 7

      Size:
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $226

      Host: Mouse

      Reactivity: H

      Applications: WB,IHC,IF,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms A2m,A2MG,Alpha 2 M,Alpha 2M,Alpha-2-M,Alpha-2-macroglobulin,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5,CPAMD5,DKFZp779B086,FWP007,S863 7
      Swissprot P01023
      Source Mouse
      Reactivity Human
      Immunogen Fusion protein of Alpha-2-macroglobulin
      Application WB,IHC,IF,ELISA
      Recommended dilution WB 1:500-1:5000, IHC 1:20-1:200, IF 1:50-1:500
      Clonality Monoclonal

      Properties

      Cellular localization Secreted.
      Tissue specificity Secreted in plasma.
      Clone No Clone:117
      Isotype IgG2a
      Purification Protein A purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 50% glycerol, PH7.3
      Background alpha-2-macroglobulin,also known as α2-macroglobulin (α2M and A2M),is a protein abundant in the plasma of vertebrates and several invertebrates. A2M is an evolutionarily conserved arm of the innate immune system. It also mediates the proliferation of T cells and macrophages. A2M acts as a nonspecific protease inhibitor involved in the host defense mechanism that inactivates both endogenous and exogenous proteases,including trypsin,thrombin and collagenase. Even though A2M is produced predominantly by the liver,it may also be expressed in the reproductive tract,heart,and brain,and may have important roles in many physiological processes and medical illnesses including Alzheimer’s disease.

      Images

      Western Blot analysis of HepG2 cells using A2M Monoclonal Antibody at dilution of 1:1000

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