ACKR2 Polyclonal Antibody

Uniprot: O00590
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30908

      Synonyms:C C chemokine receptor D6,C-C chemokine receptor D6,CC chemokine binding receptor JAB61,CC chemokine receptor D6,CCBP 2,CCBP2,CCBP2,CCR 10,CCR 9,CCR10,CCR9,Chemokine (C C motif) receptor 9,Chemokine (C C) receptor 9,Chemokine binding protein 2,Chemokine binding protein D6,Chemokine C C motif receptor 9,Chemokine C C receptor 9,Chemokine CC motif receptor 9,Chemokine CC receptor 9,Chemokine receptor 9,Chemokine receptor CCR 10,Chemokine receptor CCR 9,Chemokine receptor CCR-10,Chemokine receptor CCR-9,Chemokine receptor CCR10,Chemokine receptor CCR9,Chemokine receptor D6,Chemokine-binding protein 2,Chemokine-binding protein D6,CMKBR 9,CMKBR9,D6,hD6,MGC126678,MGC138250

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: WB,IHC-p,IF,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms C C chemokine receptor D6,C-C chemokine receptor D6,CC chemokine binding receptor JAB61,CC chemokine receptor D6,CCBP 2,CCBP2,CCBP2,CCR 10,CCR 9,CCR10,CCR9,Chemokine (C C motif) receptor 9,Chemokine (C C) receptor 9,Chemokine binding protein 2,Chemokine binding protein D6,Chemokine C C motif receptor 9,Chemokine C C receptor 9,Chemokine CC motif receptor 9,Chemokine CC receptor 9,Chemokine receptor 9,Chemokine receptor CCR 10,Chemokine receptor CCR 9,Chemokine receptor CCR-10,Chemokine receptor CCR-9,Chemokine receptor CCR10,Chemokine receptor CCR9,Chemokine receptor D6,Chemokine-binding protein 2,Chemokine-binding protein D6,CMKBR 9,CMKBR9,D6,hD6,MGC126678,MGC138250
      Swissprot O00590
      Source Rabbit
      Reactivity Human
      Immunogen Synthesized peptide derived from the C-terminal region of human Chemokine Receptor D6
      Application WB,IHC-p,IF,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cell membrane.
      Tissue specificity Expressed primarily in placenta and fetal liver, and found at very low levels in the lung and lymph node. Found in endothelial cells lining afferent lymphatics in dermis and lymph nodes. Also found in lymph nodes subcapsular and medullary sinuses, tonsillar lymphatic sinuses and lymphatics in mucosa and submucosa of small and large intestine and appendix. Also found in some malignant vascular tumors.
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.

      Images

      Western Blot analysis of HepG2 cells with ACKR2 Polyclonal Antibody

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