ADAM15 Polyclonal Antibody

Uniprot : Q13444
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    <
    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14501

      Synonyms:A disintegrin and metalloproteinase domain 15 (metargidin),A disintegrin and metalloproteinase domain 15,ADA15,ADAM 15,ADAM metallopeptidase domain 15,Adam15,and cysteine-rich protein 15,Disintegrin and metalloproteinase domain-containing protein 15,disintegrin-like,EC 3.4.24.,MDC 15,MDC-15,MDC15,Metalloprotease RGD disintegrin protein,Metalloproteinase like disintegrin like and cysteine rich protein 15,Metalloproteinase-like,Metargidin

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms A disintegrin and metalloproteinase domain 15 (metargidin),A disintegrin and metalloproteinase domain 15,ADA15,ADAM 15,ADAM metallopeptidase domain 15,Adam15,and cysteine-rich protein 15,Disintegrin and metalloproteinase domain-containing protein 15,disintegrin-like,EC 3.4.24.,MDC 15,MDC-15,MDC15,Metalloprotease RGD disintegrin protein,Metalloproteinase like disintegrin like and cysteine rich protein 15,Metalloproteinase-like,Metargidin
      Swissprot Q13444
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human ADAM15
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:25-1:100
      Concentration 0.3 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Endomembrane system. Cell junction>adherens junction. Cell projection>cilium>flagellum. Cytoplasmic vesicle>secretory vesicle>acrosome. The majority of the protein is localized in a perinuclear compartment which may correspond to the trans-Golgi network or the late endosome. The pro-protein is the major detectable form on the cell surface, whereas the majority of the protein in the cell is processed.
      Tissue specificity Expressed in colon and small intestine. Expressed in airway smooth muscle and glomerular mesangial cells (at protein level). Ubiquitously expressed. Overexpressed in atherosclerotic lesions. Constitutively expressed in cultured endothelium and smooth muscle. Expressed in chondrocytes. Expressed in airway smooth muscle and glomerular mesangial cells.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

      Images

      Immunohistochemistry of paraffin-embedded Human brain tissue using ADAM15 Polyclonal Antibody at dilution 1:35

      Immunohistochemistry of paraffin-embedded Human lung cancer tissue using ADAM15 Polyclonal Antibody at dilution 1:35

      • Show all (0)
      • Reviews (0)
      • Q&A (0)
      ... Show All Show Less
      MSDS for ELISA

      Browsing History


        People Also Bought