Current Position:Home>>Antibodies>>FCM Antibodies>> AF488 Anti-Human TCR γ/δ Antibody[B1] E-AB-F1145L
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Add to cart Bulk requestAlternate Names | T cell receptor γ/δ, γ/δ TCR, TCR-γ/δ |
References |
1. Lanier LL, et al. 1987. J. Clin. Immunol. 7:429.
2. Spencer J, et al. 1989. Eur. J. Immunol. 19:1335. 3. Uyemura K, et al. 1991. J. Exp. Med. 174:683. 4. Spada FM, et al. 2000. J. Exp. Med. 191:907. |
Form | Liquid |
Clone No. | B1(See Other Available Formats) |
Host | Mouse |
Isotype | Mouse IgG1, κ |
Isotype Control | AF488 Mouse IgG1, κ Isotype Control[MOPC-21] [Product E-AB-F09792L] |
Reactivity | Human |
Application | FCM (See the Application Description) |
Storage Buffer | PBS with 0.05% Proclin300, 1% BSA |
Recommended Use | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
Shipping | Biological ice pack at 4℃ |
Stability & Storage | Keep as concentrated solution. Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Conjugation | AF488 |
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CD49d is a 150 kD α integrin chain known as α4 integrin or VLA-4 α chain. It forms a heterodimer with either integrin β1 (α4β1, VLA-4) or β7 (α4β7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. α4β7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells. |
Related Protocols | Staining Cell Surface Targets for Flow Cytometry |
Troubleshooting |
Cat.No. | Product Name | Sizes |
E-AB-F1145C | FITC Anti-Human TCR γ/δ Antibody[B1] E-AB-F1145C | 20 Tests, 50 Tests, 100 Tests, 200 Tests |
E-AB-F1145D | PE Anti-Human TCR γ/δ Antibody[B1] E-AB-F1145D | 20 Tests, 50 Tests, 100 Tests, 200 Tests |
E-AB-F1145E | APC Anti-Human TCR γ/δ Antibody[B1] E-AB-F1145E | 20 Tests, 50 Tests, 100 Tests, 200 Tests |
E-AB-F1145G | PE/Cyanine5 Anti-Human TCR γ/δ Antibody[B1] E-AB-F1145G | 20 Tests, 50 Tests, 100 Tests, 200 Tests |
E-AB-F1145H | PE/Cyanine7 Anti-Human TCR γ/δ Antibody[B1] E-AB-F1145H | 20 Tests, 50 Tests, 100 Tests, 200 Tests |
E-AB-F1145I | PE/Cyanine5.5 Anti-Human TCR γ/δ Antibody[B1] E-AB-F1145I | 20 Tests, 50 Tests, 100 Tests, 200 Tests |
E-AB-F1145J | PerCP/Cyanine5.5 Anti-Human TCR γ/δ Antibody[B1] E-AB-F1145J | 20 Tests, 50 Tests, 100 Tests, 200 Tests |
E-AB-F1145L | AF488 Anti-Human TCR γ/δ Antibody[B1] E-AB-F1145L | 20 Tests, 50 Tests, 100 Tests, 200 Tests |
E-AB-F1145M | AF647 Anti-Human TCR γ/δ Antibody[B1] E-AB-F1145M | 20 Tests, 50 Tests, 100 Tests, 200 Tests |