AF647 Anti-Human CD127/IL-7RA Antibody[A019D5]

Uniprot : P16871
    • Flow cytometry antibody-Elabscience
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    • Flow cytometry antibody-Elabscience
    • Flow cytometry antibody-Elabscience

      Catalog number:E-AB-F1152M

      Synonyms:Interleukin-7 receptor subunit alpha,IL-7RA,CDw127,CD127,IL-7Rα

      Size:
      • 20 Tests
      • 50 Tests
      • 100 Tests
      • 200 Tests
      Qty:
      - +
      Price: $115

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      (See Other Available Formats)

      Antigen Information

      Alternate Names Interleukin-7 receptor subunit alpha,IL-7RA,CDw127,CD127,IL-7Rα
      Uniprot ID P16871
      Background CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.

      Product Details

      Form Liquid
      Clone No. A019D5 (See Other Available Formats)
      Host Mouse
      Isotype Mouse IgG1, κ
      Isotype Control AF647 Mouse IgG1, κ Isotype Control[MOPC-21] [Product E-AB-F09792M]
      Reactivity Human
      Application FCM (See the Application Description)
      Storage Buffer PBS with 0.05% Proclin300, 1% BSA
      Shipping Biological ice pack at 4 ℃
      Stability & Storage Keep as concentrated solution.
      Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
      Centrifuge before opening to ensure complete recovery of vial contents.
      This product is guaranteed up to one year from purchase.

      Fluorophore

      Conjugation: AF647

      Recommended Use

      Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 µl staining volume or per 100 µl of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

      References

      1. Sudo T, et al. 1993. P. Natl. Acad. Sci. USA 90:9125.
      2. He YW and Malek TR. 1998. Crit. Rev. Immunol. 18:503.
      3. Huster KM, et al. 2004. P. Natl. Acad. Sci. USA 101:5610.
      4. Pillai M, et al. 2004. Leukemia Lymphoma 45:2403.
      5. Morrissey PJ, et al. 1989. J. Exp. Med. 169:707.
      6. Liu W, et al. 2006. J. Exp. Med. 203:1701.

      Additional Products

      Catalog No. Product Name Sizes
      E-AB-F1152C FITC Anti-Human CD127/IL-7RA Antibody[A019D5] 20 Tests, 50 Tests, 100 Tests, 200 Tests
      E-AB-F1152D PE Anti-Human CD127/IL-7RA Antibody[A019D5] 20 Tests, 50 Tests, 100 Tests, 200 Tests
      E-AB-F1152E APC Anti-Human CD127/IL-7RA Antibody[A019D5] 20 Tests, 50 Tests, 100 Tests, 200 Tests
      E-AB-F1152G PE/Cyanine5 Anti-Human CD127/IL-7RA Antibody[A019D5] 20 Tests, 50 Tests, 100 Tests, 200 Tests
      E-AB-F1152H PE/Cyanine7 Anti-Human CD127/IL-7RA Antibody[A019D5] 20 Tests, 50 Tests, 100 Tests, 200 Tests
      E-AB-F1152I PE/Cyanine5.5 Anti-Human CD127/IL-7RA Antibody[A019D5] 20 Tests, 50 Tests, 100 Tests, 200 Tests
      E-AB-F1152J PerCP/Cyanine5.5 Anti-Human CD127/IL-7RA Antibody[A019D5] 20 Tests, 50 Tests, 100 Tests, 200 Tests
      E-AB-F1152L AF488 Anti-Human CD127/IL-7RA Antibody[A019D5] 20 Tests, 50 Tests, 100 Tests, 200 Tests
      E-AB-F1152M AF647 Anti-Human CD127/IL-7RA Antibody[A019D5] 20 Tests, 50 Tests, 100 Tests, 200 Tests
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