AF647 Anti-Human TCR γ/δ Antibody[B1]

    • Flow cytometry antibody-Elabscience
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    • Flow cytometry antibody-Elabscience
    • Flow cytometry antibody-Elabscience

      Catalog number:E-AB-F1145M

      Synonyms:T cell receptor γ/δ, γ/δ TCR, TCR-γ/δ

      Size:
      • 20 Tests
      • 50 Tests
      • 100 Tests
      • 200 Tests
      Qty:
      - +
      Price: $115

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      (See Other Available Formats)

      Antigen Information

      Alternate Names T cell receptor γ/δ, γ/δ TCR, TCR-γ/δ
      Background CD49d is a 150 kD α integrin chain known as α4 integrin or VLA-4 α chain. It forms a heterodimer with either integrin β1 (α4β1, VLA-4) or β7 (α4β7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. α4β7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells.

      Product Details

      Form Liquid
      Clone No. B1 (See Other Available Formats)
      Host Mouse
      Isotype Mouse IgG1, κ
      Isotype Control AF647 Mouse IgG1, κ Isotype Control[MOPC-21] [Product E-AB-F09792M]
      Reactivity Human
      Application FCM (See the Application Description)
      Storage Buffer PBS with 0.05% Proclin300, 1% BSA
      Shipping Biological ice pack at 4 ℃
      Stability & Storage Keep as concentrated solution.
      Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
      Centrifuge before opening to ensure complete recovery of vial contents.
      This product is guaranteed up to one year from purchase.

      Fluorophore

      Conjugation: AF647

      Recommended Use

      Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 µl staining volume or per 100 µl of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

      References

      1. Lanier LL, et al. 1987. J. Clin. Immunol. 7:429.
      2. Spencer J, et al. 1989. Eur. J. Immunol. 19:1335.
      3. Uyemura K, et al. 1991. J. Exp. Med. 174:683.
      4. Spada FM, et al. 2000. J. Exp. Med. 191:907.

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      E-AB-F1145I PE/Cyanine5.5 Anti-Human TCR γ/δ Antibody[B1] 20 Tests, 50 Tests, 100 Tests, 200 Tests
      E-AB-F1145J PerCP/Cyanine5.5 Anti-Human TCR γ/δ Antibody[B1] 20 Tests, 50 Tests, 100 Tests, 200 Tests
      E-AB-F1145L AF488 Anti-Human TCR γ/δ Antibody[B1] 20 Tests, 50 Tests, 100 Tests, 200 Tests
      E-AB-F1145M AF647 Anti-Human TCR γ/δ Antibody[B1] 20 Tests, 50 Tests, 100 Tests, 200 Tests
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