AIFM3 Polyclonal Antibody

Uniprot : Q96NN9
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14762

      Synonyms:AIFL,Aifm3,AIFM3,Apoptosis inducing factor 3,Apoptosis inducing factor like,Apoptosis inducing factor like protein,Apoptosis inducing factor,mitochondrion associated,Apoptosis-inducing factor 3,Apoptosis-inducing factor-like protein,FLJ30473,FLJ45137

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms AIFL,Aifm3,AIFM3,Apoptosis inducing factor 3,Apoptosis inducing factor like,Apoptosis inducing factor like protein,Apoptosis inducing factor,mitochondrion associated,Apoptosis-inducing factor 3,Apoptosis-inducing factor-like protein,FLJ30473,FLJ45137
      Swissprot Q96NN9
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Recombinant protein of human AIFM3
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:200-1:1000, IHC 1:50-1:200
      Concentration 0.6 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Mitochondrion. Does not translocate to the nucleus upon induction of apoptosis.
      Tissue specificity Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background AIFL (apoptosis-inducing factor-like), also known as AIFM3 (apoptosis-inducing factor, mitochondrion-associated, 3), is a 605 amino acid protein that localizes to the mitochondrion and contains one rieske domain. Expressed ubiquitously in tissues including liver, thymus, ovary, bone marrow and cerebral cortex, AIFL functions to induce apoptosis, specifically through a caspase-dependent pathway, and may also play a role in the modulation of mitochondrial membrane potential. Multiple isoforms of AIFL exist due to alternative splicing events. The gene encoding AIFL maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome.

      Images

      Western Blot analysis of Mouse thymus tissue using AIFM3 Polyclonal Antibody at dilution of 1:240

      Immunohistochemistry of paraffin-embedded Human thyroid cancer using AIFM3 Polyclonal Antibody at dilution of 1:40

      Immunohistochemistry of paraffin-embedded Human colon cancer using AIFM3 Polyclonal Antibody at dilution of 1:40

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