ALK/CD246 Monoclonal Antibody

  • monoclonal antibody-Elabscience
  • monoclonal antibody-Elabscience
  • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
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    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience

      Catalog number:E-AB-27016

      Synonyms:Alk,ALK tyrosine kinase receptor,ALK/EML4 fusion gene,included,ALK/NPM1 fusion gene,included,ALK,anaplastic lymphoma kinase (Ki-1),Anaplastic lymphoma kinase,Anaplastic lymphoma kinase Ki1,anaplastic lymphoma receptor tyrosine kinase,CD 246,CD246,CD246 antigen,EC 2.7.10.1,Ki 1,Ki1,mutant anaplastic lymphoma kinase,NBLST 3,NBLST3,Tcrz,TFG/ALK

      Size:
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $185

      Host: Mouse

      Reactivity: H

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms Alk,ALK tyrosine kinase receptor,ALK/EML4 fusion gene,included,ALK/NPM1 fusion gene,included,ALK,anaplastic lymphoma kinase (Ki-1),Anaplastic lymphoma kinase,Anaplastic lymphoma kinase Ki1,anaplastic lymphoma receptor tyrosine kinase,CD 246,CD246,CD246 antigen,EC 2.7.10.1,Ki 1,Ki1,mutant anaplastic lymphoma kinase,NBLST 3,NBLST3,Tcrz,TFG/ALK
      Swissprot Q9UM73
      Source Mouse
      Reactivity Human
      Immunogen Fusion protein of ALK/CD246
      Application WB,IHC,ELISA
      Recommended dilution WB 1:500-1:5000, IHC 1:20-1:200
      Clonality Monoclonal

      Properties

      Clone No Clone:66
      Isotype IgG2a
      Purification Protein A purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 50% glycerol, PH7.3
      Background ALK,also named as CD246,is a receptor tyrosine kinase (RTK) that belongs to the protein kinase superfamily. ALK is usually found in the nervous system and appears to play an important role in the normal development and function of the nervous system. ALK was originally identified as part of the NPM (Nucleophosmin)-ALK oncogenic fusion protein,resulting from the (2;5)(p23;q35) translocation that is frequently associated with anaplastic large-cell lymphoma (ALCL). The EML4 (echinoderm microtubule-associated protein-like 4)-ALK fusion protein have been described in non-small-cell lung cancer (NSCLC),this transforming fusion kinase is a promising candidate for a therapeutic target as well as for a diagnostic molecular marker in NSCLC .

      Images

      Western Blot analysis of Recombinant protein using ALK/CD246 Monoclonal Antibody at dilution of 1:1000

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