Alpha-1-Antitrypsin Monoclonal Antibody

  • monoclonal antibody-Elabscience
  • monoclonal antibody-Elabscience
  • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
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    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience

      Catalog number:E-AB-27020

      Synonyms:A1A,A1AT,A1AT,AAT,Alpha 1 antiproteinase,Alpha 1 antitrypsin,Alpha 1 antitrypsin null,Alpha 1 protease inhibitor,Alpha-1 protease inhibitor,Alpha-1-antiproteinase,alpha1 proteinase inhibitor,Alpha1AT,Dom1,PI,PI1,PRO2275,Serine (or cysteine) proteinase inhibitor clade A member 1,Serine protease inhibitor 1-1,Serine protease inhibitor A1a,Serpin A1,Serpin A1a,Serpin peptidase inhibitor clade A member 1,Serpina1,Short peptide from AAT,SPAAT,Spi1-1

      Size:
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $185

      Host: Mouse

      Reactivity: H,R

      Applications: WB,IHC,IF,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms A1A,A1AT,A1AT,AAT,Alpha 1 antiproteinase,Alpha 1 antitrypsin,Alpha 1 antitrypsin null,Alpha 1 protease inhibitor,Alpha-1 protease inhibitor,Alpha-1-antiproteinase,alpha1 proteinase inhibitor,Alpha1AT,Dom1,PI,PI1,PRO2275,Serine (or cysteine) proteinase inhibitor clade A member 1,Serine protease inhibitor 1-1,Serine protease inhibitor A1a,Serpin A1,Serpin A1a,Serpin peptidase inhibitor clade A member 1,Serpina1,Short peptide from AAT,SPAAT,Spi1-1
      Swissprot P01009
      Source Mouse
      Reactivity Human,Rat
      Immunogen Fusion protein of Alpha-1-Antitrypsin
      Application WB,IHC,IF,ELISA
      Recommended dilution WB 1:5000-1:20000, IHC 1:500-1:1000, IF 1:20-1:200
      Clonality Monoclonal

      Properties

      Clone No Clone:447
      Isotype IgG1
      Purification Protein G purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 50% glycerol, PH7.3
      Background SERPINA1 is the gene for a protein called alpha-1-antitrypsin (AAT),which is a serine protease inhibitor whose targets include elastase,plasmin,thrombin,trypsin,chymotrypsin,and plasminogen activator. AAT is a glycoprotein synthesized primarily by hepatocytes,with smaller amountssynthesized by intestinal epithelial cells,neutrophils,pulmonary alveolar cells and macrophages. AAT is the most abundant,endogenous serine protease inhibitor in blood circulation and it has been implicated in regulating vital fluid phase biological events such as blood coagulation,fibrinolysis,complement activation,apoptosis,reproduction,tumor progression and inflammatory response. The primary function of AAT is thought to be the inactivation of neutrophil elastase and other endogenous serine proteases. Defects in SERPINA1 can cause emphysema or liver disease.

      Images

      Western Blot analysis of HepG2 cells using Alpha-1-Antitrypsin Monoclonal Antibody at dilution of 1:20000

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