Anti-Human CD16 Monoclonal Antibody(APC Conjugated)[CB16]

Uniprot : P08637
    • Flow cytometry antibody-Elabscience
    • Flow cytometry antibody-Elabscience
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    • Flow cytometry antibody-Elabscience
    • Flow cytometry antibody-Elabscience
    • Flow cytometry antibody-Elabscience
    • Flow cytometry antibody-Elabscience

      Catalog number:E-AB-F1005E

      Synonyms:Low affinity immunoglobulin gamma Fc region receptor III-A,FCGR3A,CD16a antigen,Fc-gamma RIII-alpha,Fc-gamma RIII,Fc-gamma RIIIa,FcRIII,FcRIIIa,FcR-10,IgG Fc receptor III-2,CD16a

      Size:
      • 20 Tests
      • 50 Tests
      • 100 Tests
      • 200 Tests
      Qty:
      - +
      Price: $55

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Antigen Information

      Alternate Names Low affinity immunoglobulin gamma Fc region receptor III-A,FCGR3A,CD16a antigen,Fc-gamma RIII-alpha,Fc-gamma RIII,Fc-gamma RIIIa,FcRIII,FcRIIIa,FcR-10,IgG Fc receptor III-2,CD16a
      Uniprot ID P08637
      Background CD16 is known as low affinity IgG receptor III (FcγRIII). It is expressed as two distinct forms (CD16a and CD16b). CD16a (FcγRIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. It is expressed on the surface of NK cells, activated monocytes, macrophages, and placental trophoblasts in humans. CD16b (FcγRIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein. Its extracellular domain is over 95% homologous to that of CD16a, and it is expressed specifically on neutrophils. CD16 binds aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC).

      Product Details

      Form Liquid
      Clone No. CB16 (See Other Available Formats)
      Host Mouse
      Isotype Mouse IgG1, κ
      Isotype Control Mouse IgG1, κ Isotype Control(APC Conjugated)[MOPC-21] [Product E-AB-F09792E]
      Reactivity Human
      Application FCM (See the Application Description)
      Storage Buffer PBS with 0.05% Proclin300, 1% BSA
      Shipping Biological ice pack at 4 ℃
      Stability & Storage Keep as concentrated solution.
      Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
      Centrifuge before opening to ensure complete recovery of vial contents.
      This product is guaranteed up to one year from purchase.

      Fluorophore

      Conjugation: APC

      Recommended Use

      Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 µl staining volume or per 100 µl of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

      Product Data

      • Human pheripheral blood cells are stained with Anti-Human CD16 Monoclonal Antibody(APC Conjugated)(filled gray histogram). Unstained pheripheral blood cells (blank black histogram) are used as control.

      References

      1. Fleit H, et al. 1982. P. Natl. Acad. Sci. USA 79:3275.
      2. Stroncek D, et al. 1991. Blood 77:1572.
      3. Wirthmueller U, et al. 1992. J. Exp. Med. 175:1381.

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