Anti-Mouse CD209b Monoclonal Antibody(Biotin Conjugated)[22D1]

Uniprot : Q8CJ91
    • Flow cytometry antibody-Elabscience
    • Flow cytometry antibody-Elabscience
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    • Flow cytometry antibody-Elabscience
    • Flow cytometry antibody-Elabscience
    • Flow cytometry antibody-Elabscience
    • Flow cytometry antibody-Elabscience

      Catalog number:E-AB-F1022B

      Synonyms:CD209 antigen-like protein B,Cd209b,DC-SIGN-related protein 1,DC-SIGNR1,OtB7,CD209,Cd209b

      Size:
      • 50 μg
      • 100 μg
      Qty:
      - +
      Price: $90

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual
      (See Other Available Formats)

      Antigen Information

      Alternate Names CD209 antigen-like protein B,Cd209b,DC-SIGN-related protein 1,DC-SIGNR1,OtB7,CD209,Cd209b
      Uniprot ID Q8CJ91
      Background CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway.

      Product Details

      Form Liquid
      Concentration 0.5 mg/mL
      Clone No. 22D1 (See Other Available Formats)
      Host Armenian Hamster
      Isotype Armenian Hamster IgG
      Isotype Control Armenian Hamster IgG Isotype Control(Biotin Conjugated)[PIP] [Product E-AB-F09853B]
      Reactivity Mouse
      Application FCM (See the Application Description)
      Storage Buffer PBS with 0.05% Proclin300, 1% BSA
      Shipping Biological ice pack at 4 ℃
      Stability & Storage Keep as concentrated solution.
      Store at 2~8℃ . Do not freeze.
      Centrifuge before opening to ensure complete recovery of vial contents.
      This product is guaranteed up to one year from purchase.

      Recommended Use

      Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per 106 cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

      References

      1. Zhou Y, et al. 2010. Nat. Med. 16:1128.
      2. Saunders SP, et al. 2010. J. Immunol. 184:2627.
      3. Silva-Martin N, et al. 2009. Acta. Crystallogr. Sect. F. Struct. Biol. Cryst. Commun. 65:1264.
      4. Saunders SP, et al. 2009. Infect. Immun. 77:399.
      5. Park JY, et al. 2009. Neurosci. Lett. 450:246.
      6. Lanoue A, et al. J. Exp. Med. 200:1383.

      Additional Products

      Catalog No. Product Name Sizes
      E-AB-F10220 AF/LE Purified Anti-Mouse CD209b Monoclonal Antibody 50 μg, 500 μg, 1 mg
      E-AB-F1022A Purified Anti-Mouse CD209b Monoclonal Antibody[22D1] 50 μg, 100 μg
      E-AB-F1022B Anti-Mouse CD209b Monoclonal Antibody(Biotin Conjugated)[22D1] 50 μg, 100 μg
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