APC5 Polyclonal Antibody

Uniprot : Q9UJX4
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14579

      Synonyms:2510006G12Rik,AA408751,AA536819,AA986414,ANAPC 5,ANAPC5,Anaphase promoting complex subunit 5,Anaphase-promoting complex subunit 5,Apc 5,APC5,APC5,Cyclosome subunit 5,PDL 108,PDL108,Periodontal ligament fibroblast protein,RMC1

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms 2510006G12Rik,AA408751,AA536819,AA986414,ANAPC 5,ANAPC5,Anaphase promoting complex subunit 5,Anaphase-promoting complex subunit 5,Apc 5,APC5,APC5,Cyclosome subunit 5,PDL 108,PDL108,Periodontal ligament fibroblast protein,RMC1
      Swissprot Q9UJX4
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human ANAPC5
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:200-1:1000, IHC 1:50-1:200
      Concentration 0.3 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytosol,Nucleus,anaphase-promoting complex,nucleoplasm,nucleus
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. 

      Images

      Western Blot analysis of NIH/3T3 cell using APC5 Polyclonal Antibody at dilution of 1:187.5

      Immunohistochemistry of paraffin-embedded Human thyroid cancer using APC5 Polyclonal Antibody at dilution of 1:30

      Immunohistochemistry of paraffin-embedded Human liver cancer using APC5 Polyclonal Antibody at dilution of 1:30

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