API5 Polyclonal Antibody

Uniprot: Q9BZZ5
  • polyclonal antibody-Elabscience
  • polyclonal antibody-Elabscience
  • polyclonal antibody-Elabscience
  • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30524

      Synonyms:AAC 11,AAC-11,AAC11,Antiapoptosis clone 11 protein,API 5,API-5,api5,API5 like 1,API5,API5L1,Apoptosis inhibitor 5,Cell migration inducing gene 8 protein,Cell migration-inducing gene 8 protein,Fibroblast growth factor 2 interacting factor 2,Fibroblast growth factor 2-interacting factor,FIF,MIG 8,MIG8,Migration inducing protein MIG8,Protein XAGL

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,IHC-p,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms AAC 11,AAC-11,AAC11,Antiapoptosis clone 11 protein,API 5,API-5,api5,API5 like 1,API5,API5L1,Apoptosis inhibitor 5,Cell migration inducing gene 8 protein,Cell migration-inducing gene 8 protein,Fibroblast growth factor 2 interacting factor 2,Fibroblast growth factor 2-interacting factor,FIF,MIG 8,MIG8,Migration inducing protein MIG8,Protein XAGL
      Swissprot Q9BZZ5
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Synthesized peptide derived from the C-terminal region of human API5
      Application WB,IHC-p,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm and Nucleus. Cytoplasm. Mainly nuclear. Can also be cytoplasmic.
      Tissue specificity Expressed in all tissues tested, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highest levels in heart, pancreas and placenta. Highly expressed in several cancers. Preferentially expressed in squamous cell carcinoma versus adenocarcinoma in non-small cell lung cancer.
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

      Images

      Western Blot analysis of 3T3 cells using API5 Polyclonal Antibody at dilution of 1:1000.

      Western Blot analysis of 293 cells using API5 Polyclonal Antibody at dilution of 1:1000.

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