APLF Polyclonal Antibody

Uniprot: Q8IW19
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    <
    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30526

      Synonyms:2010301N04Rik,AI452191,Aplf,APLF,Aprataxin and PNK-like factor,Apurinic-apyrimidinic endonuclease APLF,C2orf13,PNK and APTX like FHA protein,PNK and APTX-like FHA domain-containing protein,RGD1565557,XIP1,XRCC1 interacting protein 1,XRCC1-interacting protein 1

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,IHC-p,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms 2010301N04Rik,AI452191,Aplf,APLF,Aprataxin and PNK-like factor,Apurinic-apyrimidinic endonuclease APLF,C2orf13,PNK and APTX like FHA protein,PNK and APTX-like FHA domain-containing protein,RGD1565557,XIP1,XRCC1 interacting protein 1,XRCC1-interacting protein 1
      Swissprot Q8IW19
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Synthesized peptide derived from human APLF around the non-phosphorylation site of S116.
      Application WB,IHC-p,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus. Cytoplasm>cytosol. Localizes to DNA damage sites. Accumulates at single-strand breaks and double-strand breaks via the PBZ-type zinc fingers.
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks. Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro.

      Images

      Western Blot analysis of HT-29 cells with APLF Polyclonal Antibody.

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