APLP2 Polyclonal Antibody

Uniprot: Q06481
  • polyclonal antibody-Elabscience
  • polyclonal antibody-Elabscience
  • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30527

      Synonyms:amyloid beta (A4) precursor like protein 2,Amyloid like protein 2,Amyloid precursor protein homolog HSD 2,amyloid precursor protein homolog HSD2,Amyloid protein homolog,Amyloid-like protein 2,APLP-2,Aplp2,APLP2,APPH,APPL2,CDEBP,CDEI box binding protein,CDEI box-binding protein

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IHC-p,ELISA

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      Overview

      Synonyms amyloid beta (A4) precursor like protein 2,Amyloid like protein 2,Amyloid precursor protein homolog HSD 2,amyloid precursor protein homolog HSD2,Amyloid protein homolog,Amyloid-like protein 2,APLP-2,Aplp2,APLP2,APPH,APPL2,CDEBP,CDEI box binding protein,CDEI box-binding protein
      Swissprot Q06481
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Synthesized peptide derived from the Internal region of human APLP-2
      Application WB,IHC-p,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cell membrane. Nucleus.
      Tissue specificity Expressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

      Images

      Western Blot analysis of 293, 3T3 cells using APLP2 Polyclonal Antibody at dilution of 1:2000.

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