AR Polyclonal Antibody

Uniprot : P10275
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30544

      Synonyms:AIS,ANDR,Androgen nuclear receptor variant 2,Androgen receptor (dihydrotestosterone receptor,testicular feminization,spinal and bulbar muscular atrophy,Kennedy disease),Androgen receptor,androgen receptor splice variant 4b,AR,AR8,DHTR,Dihydro testosterone receptor,Dihydrotestosterone receptor (DHTR),Dihydrotestosterone receptor,HUMARA,HYSP1,KD,Kennedy disease (KD),NR3C4,Nuclear receptor subfamily 3 group C member 4 (NR3C4),Nuclear receptor subfamily 3 group C member 4,SBMA,SMAX1,Spinal and bulbar muscular atrophy (SBMA),Spinal and bulbar muscular atrophy,Testicular Feminization (TFM),TFM

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms AIS,ANDR,Androgen nuclear receptor variant 2,Androgen receptor (dihydrotestosterone receptor,testicular feminization,spinal and bulbar muscular atrophy,Kennedy disease),Androgen receptor,androgen receptor splice variant 4b,AR,AR8,DHTR,Dihydro testosterone receptor,Dihydrotestosterone receptor (DHTR),Dihydrotestosterone receptor,HUMARA,HYSP1,KD,Kennedy disease (KD),NR3C4,Nuclear receptor subfamily 3 group C member 4 (NR3C4),Nuclear receptor subfamily 3 group C member 4,SBMA,SMAX1,Spinal and bulbar muscular atrophy (SBMA),Spinal and bulbar muscular atrophy,Testicular Feminization (TFM),TFM
      Swissprot P10275
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Synthesized peptide derived from human AR around the non-phosphorylation site of Y363.
      Application WB,ELISA
      Recommended dilution WB 1:500-1:2000, ELISA 1:20000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus. Cytoplasm. Predominantly cytoplasmic in unligated form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unligated form in the presence of RACK1.
      Tissue specificity Isoform 2 is mainly expressed in heart and skeletal muscle (PubMed:15634333). Isoform 3 is expressed by basal and stromal cells of prostate (at protein level) (PubMed:19244107).
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3.

      Images

      Western Blot analysis of 293T, NIH-3T3 cells using AR Polyclonal Antibody at dilution of 1:1000.

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