ARG1 Polyclonal Antibody

Uniprot: P05089
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    <
    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30551

      Synonyms:A I,Al,ARG 1,arg1,ARGI1,Arginase 1,Arginase liver,Arginase type I,Arginase,liver,Arginase-1,Arginase1,Liver type arginase,Liver-type arginase,Type I arginase

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms A I,Al,ARG 1,arg1,ARGI1,Arginase 1,Arginase liver,Arginase type I,Arginase,liver,Arginase-1,Arginase1,Liver type arginase,Liver-type arginase,Type I arginase
      Swissprot P05089
      Source Rabbit
      Reactivity Human
      Immunogen Synthesized peptide derived from the Internal region of human Arginase I
      Application WB,ELISA
      Recommended dilution WB 1:500-1:2000, ELISA 1:5000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm.
      Tissue specificity Within the immune system initially reported to be selectively expressed in granulocytes (polymorphonuclear leukocytes [PMNs]) (PubMed:15546957). Also detected in macrophages mycobacterial granulomas (PubMed:23749634). Expressed in group2 innate lymphoid cells (ILC2s) during lung disease (PubMed:27043409).
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background Liver arginase(Arginase-1) belongs to the arginase family. Hepatic arginase 1 is closely associated with alternative macrophage activation(PMID:12098359) and Arg1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia (ARGIN).

      Images

      Western Blot analysis of 293 cells with ARG1 Polyclonal Antibody

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