ARX Polyclonal Antibody

Uniprot: Q96QS3
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30569

      Synonyms:Aristaless related homeobox gene,Aristaless-related homeobox,Arx,ARX,Homeobox protein ARX,ISSX,MRX29,MRX32,MRX33,MRX36,MRX38,MRX43,MRX54,MRXS1,phox2a,PRTS

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Aristaless related homeobox gene,Aristaless-related homeobox,Arx,ARX,Homeobox protein ARX,ISSX,MRX29,MRX32,MRX33,MRX36,MRX38,MRX43,MRX54,MRXS1,phox2a,PRTS
      Swissprot Q96QS3
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Synthesized peptide derived from the Internal region of human ARX
      Application WB,ELISA
      Recommended dilution WB 1:500-1:2000, ELISA 1:5000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus.
      Tissue specificity Expressed predominantly in fetal and adult brain and skeletal muscle. Expression is specific to the telencephalon and ventral thalamus. There is an absence of expression in the cerebellum throughout development and also in adult.
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background This gene is a homeobox-containing gene expressed during development. The expressed protein contains two conserved domains, a C-peptide (or aristaless domain) and the prd-like class homeobox domain. It is a member of the group-II aristaless-related protein family whose members are expressed primarily in the central and/or peripheral nervous system. This gene is thought to be involved in CNS development. Expansion of a polyalanine tract and other mutations in this gene cause X-linked mental retardation and epilepsy.ARX (Aristaless Related Homeobox) is a Protein Coding gene. Diseases associated with ARX include Lissencephaly, X-Linked 2 and Epileptic Encephalopathy, Early Infantile, 1. Among its related pathways are Ectoderm Differentiation. GO annotations related to this gene include chromatin binding and transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding. An important paralog of this gene is RAX.

      Images

      Western Blot analysis of 293 cells with ARX Polyclonal Antibody.

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