ASB8 Polyclonal Antibody

Uniprot : Q9H765
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14748

      Synonyms:Ankyrin repeat and SOCS box containing 8,Ankyrin repeat and SOCS box protein 8,ASB 8,ASB-8,ASB8,ASB8,FLJ21255,MGC5540,OTTHUMP00000237000,OTTHUMP00000237001,OTTHUMP00000237007,OTTHUMP00000237009,OTTHUMP00000237010,PP14212

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Ankyrin repeat and SOCS box containing 8,Ankyrin repeat and SOCS box protein 8,ASB 8,ASB-8,ASB8,ASB8,FLJ21255,MGC5540,OTTHUMP00000237000,OTTHUMP00000237001,OTTHUMP00000237007,OTTHUMP00000237009,OTTHUMP00000237010,PP14212
      Swissprot Q9H765
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Recombinant protein of human ASB8
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:25-1:100
      Concentration 0.2 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm.
      Tissue specificity Highest level of expression in skeletal muscle. Also expressed in heart, brain, placenta, liver, kidney and pancreas.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background ASB-8 (ankyrin repeat and SOCS box-containing 8) is a 288 amino acid member of the ASB family that contains one SOCS box domain and four ANK repeats. Localized to the cytoplasm, ASB-8 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, working in conjunction with other proteins, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins. The highest level of ASB-8 expression has been detected in skeletal muscle. ASB-8 is also expressed in heart, brain, placenta, liver, kidney and pancreas.

      Images

      Immunohistochemistry of paraffin-embedded Human colon cancer tissue using ASB8 Polyclonal Antibody at dilution 1:30

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