ATXN1 Polyclonal Antibody

Uniprot: P54253
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30587

      Synonyms:alternative ataxin1,Ataxin-1,ATX1,ATX1,Atxn1,D6S504E,OTTHUMP00000016065,SCA1,Spinocerebellar ataxia type 1 protein

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,IHC-p,IF,ELISA

      Lead Time: 2 daysWelcome to order from local distributors.

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      Overview

      Synonyms alternative ataxin1,Ataxin-1,ATX1,ATX1,Atxn1,D6S504E,OTTHUMP00000016065,SCA1,Spinocerebellar ataxia type 1 protein
      Swissprot P54253
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Synthesized peptide derived from human Ataxin-1 around the non-phosphorylation site of Ser776.
      Application WB,IHC-p,IF,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm. Nucleus. Colocalizes with USP7 in the nucleus.
      Tissue specificity Widely expressed throughout the body.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. 

      Images

      Western Blot analysis of Mouse brain cells using ATXN1 Polyclonal Antibody at dilution of 1:500.

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