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ACLY Polyclonal Antibody

Uniprot: P53396

Catalog number:E-AB-30607

Synonyms:ACL,Acly,ACLY,ATP citrate (pro-S) lyase,ATP citrate lyase,ATP citrate synthase,ATP-citrate (pro-S-)-lyase,ATP-citrate synthase,ATPcitrate synthase,ATPCL,Citrate cleavage enzyme,CLATP,OTTHUMP00000164773

Size:

20 μL
60 μL
120 μL
200 μL

Qty:

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Price: $69

Host: Rabbit

Reactivity: H,M,R,Mk

Applications: WB,IF,ELISA

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Overview

Synonyms	ACL,Acly,ACLY,ATP citrate (pro-S) lyase,ATP citrate lyase,ATP citrate synthase,ATP-citrate (pro-S-)-lyase,ATP-citrate synthase,ATPcitrate synthase,ATPCL,Citrate cleavage enzyme,CLATP,OTTHUMP00000164773
Swissprot	P53396
Source	Rabbit
Reactivity	Human,Mouse,Rat,Monkey
Immunogen	Synthesized peptide derived from human ATP-citrate synthase around the non-phosphorylation site of Ser455.
Application	WB,IF,ELISA
Recommended dilution	WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:10000
Concentration	1mg/mL
Clonality	Polyclonal

Properties

Cellular localization	Cytoplasm.
Isotype	IgG
Purification	Affinity purification
Conjugation	Unconjugated
Storage instructions	Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer	PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Background	ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene.