Synonyms:B-Myb,BMyB,MGC15600,MYB L2,Myb related protein B,Myb-like protein 2,Myb-related protein B,MybB,MYBB,MYBL 2,Mybl2,v myb avian myeloblastosis viral oncogene homolog like 2,v myb myeloblastosis viral oncogene homolog (avian) like 2,v myb myeloblastosis viral oncogene homolog like 2
|Synonyms||B-Myb,BMyB,MGC15600,MYB L2,Myb related protein B,Myb-like protein 2,Myb-related protein B,MybB,MYBB,MYBL 2,Mybl2,v myb avian myeloblastosis viral oncogene homolog like 2,v myb myeloblastosis viral oncogene homolog (avian) like 2,v myb myeloblastosis viral oncogene homolog like 2|
|Immunogen||Synthesized peptide derived from human B-Myb around the non-phosphorylation site of Ser577.|
|Recommended dilution||WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:20000|
|Storage instructions||Store at -20℃. Avoid freeze / thaw cycles.|
|Storage buffer||PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4|
|Background||MYBL2 encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene.MYBL2 (MYB Proto-Oncogene Like 2) is a Protein Coding gene. Diseases associated with MYBL2 include Paraneoplastic Cerebellar Degeneration. Among its related pathways are Cell cycle Cell cycle (generic schema) and HTLV-I infection. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA polymerase II core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is MYBL1.|
Western Blot analysis of 3T3 cells using MYBL2 Polyclonal Antibody at dilution of 1:2000.