BAIAP2 Polyclonal Antibody

Uniprot : Q9UQB8
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14172

      Synonyms:BAI-associated protein 2,BAI1 associated protein 2,BAI1-associated protein 2,BAIAP 2,Baiap2,BAIP2,BAP2,Brain-specific angiogenesis inhibitor 1-associated protein 2,Fas ligand-associated factor 3,FLAF3,Insulin receptor substrate p53,Insulin receptor substrate p53/p58,Insulin receptor substrate protein of 53 kDa,IRS-58,IRSp53,IRSp53/58,Protein BAP2

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms BAI-associated protein 2,BAI1 associated protein 2,BAI1-associated protein 2,BAIAP 2,Baiap2,BAIP2,BAP2,Brain-specific angiogenesis inhibitor 1-associated protein 2,Fas ligand-associated factor 3,FLAF3,Insulin receptor substrate p53,Insulin receptor substrate p53/p58,Insulin receptor substrate protein of 53 kDa,IRS-58,IRSp53,IRSp53/58,Protein BAP2
      Swissprot Q9UQB8
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human BAIAP2
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:200-1:1000, IHC 1:50-1:200
      Concentration 0.6 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm. Membrane. Cell projection>filopodium. Cell projection>ruffle. Detected throughout the cytoplasm in the absence of specific binding partners. Detected in filopodia and close to membrane ruffles.
      Tissue specificity Isoform 1 and isoform 4 are expressed almost exclusively in brain. Isoform 4 is barely detectable in placenta, prostate and testis. A short isoform is ubiquitous, with the highest expression in liver, prostate, testis and placenta.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

      Images

      Western Blot analysis of SKOV3 cell using BAIAP2 Polyclonal Antibody at dilution of 1:350

      Immunohistochemistry of paraffin-embedded Human colon cancer using BAIAP2 Polyclonal Antibody at dilution of 1:30

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