BAP1 Polyclonal Antibody
Price: $ 399
Price: $ 240
Price: $ 143
Price: $ 73
Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Rabbit
- Reactivity: Human; Mouse; Rat
- Applications: IHC
Add to cart
For research use only. Order now, ship in 3 days
Product Details
Verified Samples |
Verified Samples in IHC:Human esophagus cancer,Human breast cancer |
Dilution |
IHC 1:40-1:200 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Fusion protein of human BAP1 |
Abbre | BAP1 |
Synonyms | BAP 1;Bap1;BAP1;BRCA 1 associated protein 1;BRCA1 associated protein 1;BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase);BRCA1-associated protein 1;Cerebral protein 13;Cerebral protein 6;DKFZp686N04275;FLJ35406;FLJ37180;HUCEP 13;Hucep 6;HUCEP13;Hucep6;KIAA0272;TPDS;Ubiquitin carboxy terminal hydrolase;Ubiquitin carboxyl terminal hydrolase BAP 1;Ubiquitin carboxyl terminal hydrolase BAP1;Ubiquitin carboxyl-terminal hydrolase BAP1;UCHL2 |
Swissprot | |
Cellular Localization | Cytoplasm. Nucleus. Mainly nuclear. Binds to chromatin. |
Concentration | 0.8 mg/mL |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Cancer; Cell Biology; Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Ice bag |
background | This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. |
Citations
-
Expression levels of BAP1, OGT, and YY1 genes in patients with eyelid tumors
IF:0.401
Journal:Turkish Journal of Biochemistry-Turk Biyokimya Dergisi
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol