BCAS2 Polyclonal Antibody

Uniprot: O75934
  • polyclonal antibody-Elabscience
  • polyclonal antibody-Elabscience
  • polyclonal antibody-Elabscience
  • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    <
    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30632

      Synonyms:bcas2,Breast carcinoma amplified sequence 2,Breast carcinoma-amplified sequence 2,DAM1,DNA amplified in mammary carcinoma 1 protein,MGC7712,Pre mRNA splicing factor SPF27,Pre-mRNA-splicing factor spf27,Snt309,SPF27,SPF27,Spliceosome associated protein amplified in breast cancer,Spliceosome associated protein SPF 27,Spliceosome-associated protein SPF 27

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R,Mk

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms bcas2,Breast carcinoma amplified sequence 2,Breast carcinoma-amplified sequence 2,DAM1,DNA amplified in mammary carcinoma 1 protein,MGC7712,Pre mRNA splicing factor SPF27,Pre-mRNA-splicing factor spf27,Snt309,SPF27,SPF27,Spliceosome associated protein amplified in breast cancer,Spliceosome associated protein SPF 27,Spliceosome-associated protein SPF 27
      Swissprot O75934
      Source Rabbit
      Reactivity Human,Mouse,Rat,Monkey
      Immunogen Synthesized peptide derived from the C-terminal region of human BCAS2
      Application WB,ELISA
      Recommended dilution WB 1:500-1:2000, ELISA 1:5000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus>nucleolus.
      Tissue specificity Ubiquitously expressed.
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background BCAS2 (breast carcinoma amplified sequence 2), also designated DAM1 (DNA amplified in mammary carcinoma 1 protein) or spliceosome-associated SPF 27, is a ubiquitously expressed nuclear protein that was originally identified as being overexpressed in various breast cancer cell lines. BCAS2 is now known to be a component of the spliceosome, participating in the removal of introns from mRNA precursors. BCAS2 specifically interacts (in a ligand-independent manner) with TR∫ (thyroid hormone receptor beta), ERå (estrogen receptor alpha), ER∫, PR (progesterone receptor), and PPAR© (Peroxisome proliferator-activated receptor gamma). BCAS2 functions as an ER coactivator and is capable of enhancing ER-mediated transcription. This suggests that BCAS2 is involved in the development of breast cancer.

      Images

      Western Blot analysis of K562, 3T3 cells using BCAS2 Polyclonal Antibody at dilution of 1:1000.

      Western Blot analysis of Hela cells using BCAS2 Polyclonal Antibody at dilution of 1:1000.

      • Show all (0)
      • Reviews (0)
      • Q&A (0)
      ... Show All Show Less
      嘻嘻嘻

      Browsing History


        People Also Bought