BID Polyclonal Antibody

Uniprot: P55957
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30648

      Synonyms:Apoptic death agonist,Apoptotic death agonist BID,BH3 interacting domain death agonist,BH3 interacting domain death agonist p11,BH3 interacting domain death agonist p13,BH3 interacting domain death agonist p15,BH3-interacting domain death agonist p11,BID,BID isoform ES(1b),BID isoform L(2),BID isoform Si6,BID,Desmocollin type 4,FP497,Human BID coding sequence,MGC15319,MGC42355,p11 BID,p13 BID,p15 BID,p22 BID

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,IHC-p,ELISA

      Lead Time: 2 daysWelcome to order from local distributors.

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      Overview

      Synonyms Apoptic death agonist,Apoptotic death agonist BID,BH3 interacting domain death agonist,BH3 interacting domain death agonist p11,BH3 interacting domain death agonist p13,BH3 interacting domain death agonist p15,BH3-interacting domain death agonist p11,BID,BID isoform ES(1b),BID isoform L(2),BID isoform Si6,BID,Desmocollin type 4,FP497,Human BID coding sequence,MGC15319,MGC42355,p11 BID,p13 BID,p15 BID,p22 BID
      Swissprot P55957
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Synthesized peptide derived from human BID around the non-phosphorylation site of Ser78.
      Application WB,IHC-p,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm; Cytoplasm. Mitochondrion membrane. When uncleaved, it is predominantly cytoplasmic; Mitochondrion membrane. A significant proportion of isoform 2 localizes to mitochondria, it may be cleaved constitutively; Mitochondrion membrane. Associated with the mitochondrial membrane and Mitochondrion membrane. Translocates to mitochondria as an integral membrane protein.
      Tissue specificity Isoform 2 and isoform 3 are expressed in spleen, bone marrow, cerebral and cerebellar cortex. Isoform 2 is expressed in spleen, pancreas and placenta (at protein level). Isoform 3 is expressed in lung, pancreas and spleen (at protein level). Isoform 4 is expressed in lung and pancreas (at protein level).
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2.

      Images

      Western Blot analysis of Rat musle cells using BID Polyclonal Antibody at dilution of 1:1000.

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