BMI1 Polyclonal Antibody

Uniprot : P35226
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14728

      Synonyms:B lymphoma Mo MLV insertion region (mouse),B lymphoma Mo MLV insertion region 1 homolog,Bmi 1,BMI1,BMI1 polycomb ring finger oncogene,BMI1,Flvi 2/bmi 1,FLVI2/BMI1,MGC12685,Murine leukemia viral (bmi 1) oncogene homolog,Oncogene BMI 1,PCGF 4,PCGF4,Polycomb complex protein BMI 1,Polycomb complex protein BMI-1,Polycomb group protein Bmi1,Polycomb group ring finger 4,Polycomb group RING finger protein 4,RING finger protein 51,RNF 51,RNF51

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms B lymphoma Mo MLV insertion region (mouse),B lymphoma Mo MLV insertion region 1 homolog,Bmi 1,BMI1,BMI1 polycomb ring finger oncogene,BMI1,Flvi 2/bmi 1,FLVI2/BMI1,MGC12685,Murine leukemia viral (bmi 1) oncogene homolog,Oncogene BMI 1,PCGF 4,PCGF4,Polycomb complex protein BMI 1,Polycomb complex protein BMI-1,Polycomb group protein Bmi1,Polycomb group ring finger 4,Polycomb group RING finger protein 4,RING finger protein 51,RNF 51,RNF51
      Swissprot P35226
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Recombinant protein of human BMI1
      Application WB(Detection kit: E-IR-R304),ELISA
      Recommended dilution WB 1:200-1:1000
      Concentration 0.3 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus. Cytoplasm.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background BMI1 polycomb ring finger oncogene, also known as BMI1, is a protein which in humans is encoded by the BMI1gene. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

      Images

      Western Blot analysis of 231 and A549 cell, hela cell and Mouse brain tissue using BMI1 Polyclonal Antibody at dilution of 1:300

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