BMP8B Polyclonal Antibody

Uniprot: P34820
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30660

      Synonyms:BMP-8,BMP-8B,BMP8,Bmp8b,BMP8B,bone morphogenetic protein 8 (osteogenic protein 2),Bone morphogenetic protein 8,Bone morphogenetic protein 8B,dJ118J21.1 (bone morphogenetic protein 8 (osteogenic protein 2)),OP-2,OP2,Osteogenic protein 2

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms BMP-8,BMP-8B,BMP8,Bmp8b,BMP8B,bone morphogenetic protein 8 (osteogenic protein 2),Bone morphogenetic protein 8,Bone morphogenetic protein 8B,dJ118J21.1 (bone morphogenetic protein 8 (osteogenic protein 2)),OP-2,OP2,Osteogenic protein 2
      Swissprot P34820
      Source Rabbit
      Reactivity Human
      Immunogen Synthesized peptide derived from the Internal region of human BMP-8B
      Application WB,ELISA
      Recommended dilution WB 1:500-1:2000, ELISA 1:40000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Secreted.
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1.BMP8B (Bone Morphogenetic Protein 8b) is a Protein Coding gene. Diseases associated with BMP8B include Achondroplasia and Blue Color Blindness. Among its related pathways are PEDF Induced Signaling and TGF-Beta Pathway. GO annotations related to this gene include cytokine activity and transforming growth factor beta receptor binding. An important paralog of this gene is BMP8A.

      Images

      Western Blot analysis of 293 cells using BMP8B Polyclonal Antibody at dilution of 1:2000.

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