CABLES1 Polyclonal Antibody

Uniprot: Q8TDN4
  • polyclonal antibody-Elabscience
  • polyclonal antibody-Elabscience
  • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30711

      Synonyms:CABL1,CABLES,Cables1,Cdk5 and Abl enzyme substrate 1,CDK5 and ABL1 enzyme substrate 1,FLJ35924,HsT2563,IK3 1,Ik3-1,Interactor with CDK3 1

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,IHC-p,IF,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms CABL1,CABLES,Cables1,Cdk5 and Abl enzyme substrate 1,CDK5 and ABL1 enzyme substrate 1,FLJ35924,HsT2563,IK3 1,Ik3-1,Interactor with CDK3 1
      Swissprot Q8TDN4
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Synthesized peptide derived from the C-terminal region of human Cables1
      Application WB,IHC-p,IF,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus. Cytoplasm. Located in the cell body and proximal region of the developing axonal shaft of immature neurons. Located in axonal growth cone, but not in the distal part of the axon shaft or in dendritic growth cone of mature neurons.
      Tissue specificity Expressed in breast, pancreas, colon, head and neck (at protein level). Strongly decreased in more than half of cases of atypical endometrial hyperplasia and in more than 90% of endometrial cancers.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene.

      Images

      Western Blot analysis of HT29 cells using Cables1 Polyclonal Antibody at dilution of 1:500.

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