CAMK2 alpha/delta Polyclonal Antibody

Uniprot: Q9UQM7,Q13557
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30730

      Synonyms:CAMK2A,CAMKA,KIAA0968,Calcium/calmodulin-dependent protein kinase type II subunit alpha,CaM kinase II subunit alpha,CaMK-II subunit alpha,CAMK2D,CAMKD,Calcium/calmodulin-dependent protein kinase type II subunit delta,CaM kinase II

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IHC-p,IF,ELISA

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      Overview

      Synonyms CAMK2A,CAMKA,KIAA0968,Calcium/calmodulin-dependent protein kinase type II subunit alpha,CaM kinase II subunit alpha,CaMK-II subunit alpha,CAMK2D,CAMKD,Calcium/calmodulin-dependent protein kinase type II subunit delta,CaM kinase II
      Swissprot Q9UQM7,Q13557
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Synthesized peptide derived from human CaMKIIα/δ around the non-phosphorylation site of Thr286.
      Application WB,IHC-p,IF,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytosol,Mitochondrion,Nucleus,nucleoplasm,nucleus,Plasma Membrane,presynaptic membrane,Other locations:cell junction,cytoplasm,endocytic vesicle membrane,neuron projection,postsynaptic density
      Tissue specificity CAMK2D isExpressed in cardiac muscle and skeletal muscle. Isoform Delta 3, isoform Delta 2, isoform Delta 8 and isoform Delta 9 are expressed in cardiac muscle. Isoform Delta 11 is expressed in skeletal muscle.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity). Phosphorylates transcription factor FOXO3 on Ser-298 (PubMed:23805378). Activates FOXO3 transcriptional activity (By similarity).

      Images

      Western Blot analysis of NIH-3T3, K562 cells using CAMK2 alpha/delta Polyclonal Antibody at dilution of 1:500.

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