CAMK2B/G Polyclonal Antibody

Uniprot: Q13555,Q13554
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30732

      Synonyms:CAMK2G,CAMK,CAMK-II,CAMKG,Calcium/calmodulin-dependent protein kinase type II subunit gamma,CaM kinase II subunit gamma,CaMK-II subunit gamma,CAMK2B,CAM2,CAMK2,CAMKB,Calcium/calmodulin-dependent protein kinase type II subunit bet

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IF,ELISA

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      Overview

      Synonyms CAMK2G,CAMK,CAMK-II,CAMKG,Calcium/calmodulin-dependent protein kinase type II subunit gamma,CaM kinase II subunit gamma,CaMK-II subunit gamma,CAMK2B,CAM2,CAMK2,CAMKB,Calcium/calmodulin-dependent protein kinase type II subunit bet
      Swissprot Q13555,Q13554
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Synthesized peptide derived from the C-terminal region of human CaMKIIβ/γ
      Application WB,IF,ELISA
      Recommended dilution WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:20000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoskeleton,microtubule organizing center,Cytosol,Endoplasmic reticulum,sarcoplasmic reticulum membrane,Nucleus,nucleoplasm,Plasma Membrane,Other locations:cytoplasm,endocytic vesicle membrane,neuron projection
      Tissue specificity CAMK2G is Expressed in skeletal muscle.1 PublicationCAMK2B isWidely expressed. Expressed in adult and fetal brain. Expression is slightly lower in fetal brain. Expressed in skeletal muscle.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background The multifunctional CAMK2, or Ca2+/calmodulin-dependent protein kinase II, is a well known effector of calcium- and calmodulin- mediated functions. It is present in many tissues but is most abundant in the brain. CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Autophosphorylation plays an important role in the regulation of the kinase activity. CAMK2 is required for synaptic plasticity, as in Long Term Potentiation (LTP), a cellular model for learning and memory. CAMK2B is the beta chain. There are seven named isoforms produced by alternative splicing. The variable region of the CAMK2B protein is encoded by at least 7 exons (V1 to V7). Alternative splicing within this region gives rise to CAMK2B isoforms. CAMK2G is the gamma chain. CAMK2G has six alternatively spliced variants that encode six different isoforms. Some of these variants have been identified in human tumors.

      Images

      Western Blot analysis of COLO205 cells with CAMK2B/G Polyclonal Antibody

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