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CXADR Polyclonal Antibody

Uniprot: P78310

Catalog number:E-AB-30734

Synonyms:46 kD coxsackievirus and adenovirus receptor CAR protein,46 kD coxsackievirus and adenovirus receptor protein,CAR,CAR4/6,Coxsackie virus and adenovirus receptor,Coxsackie virus B receptor,Coxsackievirus and adenovirus receptor,Coxsackievirus B adenovirus receptor,Coxsackievirus B-adenovirus receptor,CVB3 binding protein,CVB3-binding protein,Cxadr,CXADR Ig like cell adhesion molecule,CXAR,hCAR,HCVADR

Size:

20 μL
60 μL
120 μL
200 μL

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Price: $69

Host: Rabbit

Reactivity: H,M,R

Applications: WB,ELISA

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Overview

Synonyms	46 kD coxsackievirus and adenovirus receptor CAR protein,46 kD coxsackievirus and adenovirus receptor protein,CAR,CAR4/6,Coxsackie virus and adenovirus receptor,Coxsackie virus B receptor,Coxsackievirus and adenovirus receptor,Coxsackievirus B adenovirus receptor,Coxsackievirus B-adenovirus receptor,CVB3 binding protein,CVB3-binding protein,Cxadr,CXADR Ig like cell adhesion molecule,CXAR,hCAR,HCVADR
Swissprot	P78310
Source	Rabbit
Reactivity	Human,Mouse,Rat
Immunogen	Synthesized peptide derived from the N-terminal region of human CAR
Application	WB,ELISA
Recommended dilution	WB 1:500-1:2000, ELISA 1:20000
Concentration	1mg/mL
Clonality	Polyclonal

Properties

Cellular localization	Secreted and Cell membrane. Cell junction>tight junction. Cell junction>adherens junction. Basolateral cell membrane. In epithelial cells localizes to the apical junction complex composced of tight and adherens junctions. In airway epithelial cells localized to basolateral membrane but not to apical surface.
Tissue specificity	Expressed in pancreas, brain, heart, small intestine, testis, prostate and at a lower level in liver and lung. Isoform 5 is ubiquitously expressed. Isoform 3 is expressed in heart, lung and pancreas. In skeletal muscle, isoform 1 is found at the neuromuscular junction and isoform 2 is found in blood vessels. In cardiac muscle, isoform 1 and isoform 2 are found at intercalated disks. In heart expressed in subendothelial layers of the vessel wall but not in the luminal endothelial surface. Expression is elevated in hearts with dilated cardiomyopathy.
Isotype	IgG
Purification	Affinity purification
Conjugation	Unconjugated
Storage instructions	Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer	PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Background	The protein encoded by this gene is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Several transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene are found on chromosomes 15, 18, and 21.