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Catalog number:E-AB-30746
Synonyms:Casein kinase 1 alpha 1,Casein kinase I isoform alpha,CK1,CK1A,CKI alpha,CKI-alpha,CKIa,Clock regulator kinase,Csnk1a1,Down regulated in lung cancer,HLCDGP1,KC1A,PRO2975
Host: Rabbit
Reactivity: H,M,R
Applications: WB,IHC-p,IF,ELISA
Lead Time: 7~10 daysWelcome to order from local distributors.
Add to cart Compare Bulk request ManualSynonyms | Casein kinase 1 alpha 1,Casein kinase I isoform alpha,CK1,CK1A,CKI alpha,CKI-alpha,CKIa,Clock regulator kinase,Csnk1a1,Down regulated in lung cancer,HLCDGP1,KC1A,PRO2975 |
Swissprot | P48729 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Synthesized peptide derived from the Internal region of human Casein Kinase Iα |
Application | WB,IHC-p,IF,ELISA |
Recommended dilution | WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000 |
Concentration | 1mg/mL |
Clonality | Polyclonal |
Cellular localization | Cytoplasm. Cytoplasm>cytoskeleton>centrosome. Chromosome>centromere>kinetochore. Nucleus speckle. Localizes to the centrosome in interphase cells, and to kinetochore fibers during mitosis. |
Isotype | IgG |
Purification | Affinity purification |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4. |
Background | Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis. |