CASP10 B/C Polyclonal Antibody

Uniprot: Q92851-2,4
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    <
    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30753

      Synonyms:ALPS2,apoptotic protease Mch-4,CASP-10,CASPA,caspase-10,FADD-like ICE2,FAS-associated death domain protein interleukin-1B-convert

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: WB,IHC-p,IF,ELISA

      Lead Time: 2 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms ALPS2,apoptotic protease Mch-4,CASP-10,CASPA,caspase-10,FADD-like ICE2,FAS-associated death domain protein interleukin-1B-convert
      Swissprot Q92851-2,4
      Source Rabbit
      Reactivity Human
      Immunogen Synthesized peptide derived from the C-terminal region of human Caspase-10 B/C
      Application WB,IHC-p,IF,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytosol,Plasma Membrane
      Tissue specificity Detectable in most tissues. Lowest expression is seen in brain, kidney, prostate, testis and colon.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-AMC and Asp-Glu-Val-Asp-AMC.Isoform C is proteolytically inactive.

      Images

      Western Blot analysis of Hela cells with CASP10 B/C Polyclonal Antibody

      • Show all (0)
      • Reviews (0)
      • Q&A (0)
      ... Show All Show Less
      嘻嘻嘻

      Browsing History


        People Also Bought