CASP7 Polyclonal Antibody

Uniprot: P55210
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30758

      Synonyms:Apoptotic protease Mch-3,Apoptotic protease MCH3,CASP-7,CASP7,CASP7,Caspase 7,Caspase 7 apoptosis related cysteine peptidase,Caspase-7 subunit p11,Caspase7,CMH 1,CMH-1,CMH1,ICE LAP3,ICE-LAP3,ICE-like apoptotic protease 3,LICE2,MCH3

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: WB,IHC-p,ELISA

      Lead Time: 2 daysWelcome to order from local distributors.

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      Overview

      Synonyms Apoptotic protease Mch-3,Apoptotic protease MCH3,CASP-7,CASP7,CASP7,Caspase 7,Caspase 7 apoptosis related cysteine peptidase,Caspase-7 subunit p11,Caspase7,CMH 1,CMH-1,CMH1,ICE LAP3,ICE-LAP3,ICE-like apoptotic protease 3,LICE2,MCH3
      Swissprot P55210
      Source Rabbit
      Reactivity Human
      Immunogen Synthesized peptide derived from the N-terminal region of human Caspase-7.
      Application WB,IHC-p,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ICC 1:200-1:1000, ELISA 1:5000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Plasma Membrane
      Tissue specificity Highly expressed in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. No expression in the brain.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Overexpression promotes programmed cell death.

      Images

      Western Blot analysis of HT29 cells using CASP7 Polyclonal Antibody at dilution of 1:1000.

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