CASP9 Polyclonal Antibody

Uniprot: P55211
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30761

      Synonyms:APAF-3,APAF3,Apoptosis related cysteine peptidase,Apoptotic protease Mch-6,Apoptotic protease-activating factor 3,CASP-9,CASP9,CASP9,Caspase 9 apoptosis related cysteine peptidase,Caspase 9 Dominant Negative,Caspase 9c,Caspase-9,Caspase-9 subunit p10,ICE LAP6,ICE like apoptotic protease 6,ICE-LAP6,ICE-like apoptotic protease 6,MCH6,PPP1R56,protein phosphatase 1,regulatory subunit 56,RNCASP9

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,Mk

      Applications: WB,ELISA

      Lead Time: 2 daysWelcome to order from local distributors.

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      Overview

      Synonyms APAF-3,APAF3,Apoptosis related cysteine peptidase,Apoptotic protease Mch-6,Apoptotic protease-activating factor 3,CASP-9,CASP9,CASP9,Caspase 9 apoptosis related cysteine peptidase,Caspase 9 Dominant Negative,Caspase 9c,Caspase-9,Caspase-9 subunit p10,ICE LAP6,ICE like apoptotic protease 6,ICE-LAP6,ICE-like apoptotic protease 6,MCH6,PPP1R56,protein phosphatase 1,regulatory subunit 56,RNCASP9
      Swissprot P55211
      Source Rabbit
      Reactivity Human,Monkey
      Immunogen Synthesized peptide derived from human Caspase-9 around the non-phosphorylation site of Ser144.
      Application WB,ELISA
      Recommended dilution WB 1:500-1:2000, ELISA 1:5000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytosol,apoptosome,cytosol,Mitochondrion,Nucleus,Other locations:protein complex
      Tissue specificity Ubiquitous, with highest expression in the heart, moderate expression in liver, skeletal muscle, and pancreas. Low levels in all other tissues. Within the heart, specifically expressed in myocytes.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

      Images

      Western Blot analysis of COS7 cells using CASP9 Polyclonal Antibody at dilution of 1:500.

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