CCDC99 Polyclonal Antibody

Uniprot: Q96EA4
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30794

      Synonyms:AA409762,Arsenite related gene 1 protein,Arsenite-related gene 1 protein,CCDC 99,Ccdc99,Coiled coil domain containing 99,Coiled-coil domain-containing protein 99,FLJ20364,FLJ40690,hSpindly,MGC124977,Protein Spindly,rhabdomyosarcoma antigen MU RMS 40.4A,Rhabdomyosarcoma antigen MU-RMS-40.4A,Rrhabdomyosarcoma antigen protein MU RMS 40.4A,SPDL1,SPDLY,Spindle apparatus coiled coil domain containing protein 1,Spindle apparatus coiled coil protein 1,Spindly,Spindly homolog

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms AA409762,Arsenite related gene 1 protein,Arsenite-related gene 1 protein,CCDC 99,Ccdc99,Coiled coil domain containing 99,Coiled-coil domain-containing protein 99,FLJ20364,FLJ40690,hSpindly,MGC124977,Protein Spindly,rhabdomyosarcoma antigen MU RMS 40.4A,Rhabdomyosarcoma antigen MU-RMS-40.4A,Rrhabdomyosarcoma antigen protein MU RMS 40.4A,SPDL1,SPDLY,Spindle apparatus coiled coil domain containing protein 1,Spindle apparatus coiled coil protein 1,Spindly,Spindly homolog
      Swissprot Q96EA4
      Source Rabbit
      Reactivity Human
      Immunogen Synthesized peptide derived from the C-terminal region of human CCDC99
      Application WB,ELISA
      Recommended dilution WB 1:500-1:2000, ELISA 1:40000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm>cytoskeleton>centrosome. Chromosome>centromere>kinetochore. Nucleus. Cytoplasm>cytoskeleton>spindle pole. Localizes to the nucleus in interphase and to the kinetochore in early prometaphase. Relocalizes to the mitotic spindle pole before metaphase and is subsequently lost from the spindle poles after chromosome congression is completed. Removal of this protein from the kinetochore requires the dynein/dynactin complex.
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. Interacts with KNTC1 and ZW10. These interactions appear weak and may be transient or indirect.

      Images

      Western Blot analysis of 3T3 cells using CCDC99 Polyclonal Antibody at dilution of 1:1000.

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