AGBL2 Polyclonal Antibody

Uniprot: Q5U5Z8
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30796

      Synonyms:AGBL2,CCP2,Cytosolic carboxypeptidase 2,ATP/GTP-binding protein-like 2

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,IHC-p,ELISA

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      Overview

      Synonyms AGBL2,CCP2,Cytosolic carboxypeptidase 2,ATP/GTP-binding protein-like 2
      Swissprot Q5U5Z8
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Synthesized peptide derived from the C-terminal region of human CCP2
      Application WB,IHC-p,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoskeleton,centriole,ciliary basal body,Cytosol
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background Metallocarboxypeptidase that may play a role in the processing of tubulin. Knockdown of AGBL2 results in a failure of the cell to detyrosinate the C-terminal EEY region of α-tubulin and indicates that, it is a candidate for the long sought after tubulin tyrosine carboxypeptidase important in regulation of microtubule dynamics. RARRES1, its interacting partners AGBL2, Eg5/KIF11, another EEY bearing protein (EB1), and the microtubule tyrosination cycle are important in tumorigenesis and identify a novel area for therapeutic intervention.

      Images

      Western Blot analysis of HuvEc cells using AGBL2 Polyclonal Antibody at dilution of 1:2000.

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