CCRL2 Polyclonal Antibody

Uniprot: O00421
  • polyclonal antibody-Elabscience
  • polyclonal antibody-Elabscience
  • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30799

      Synonyms:C-C chemokine receptor-like 2,CCRL2,CCRL2,Chemokine (C-C motif) receptor like 2,Chemokine receptor CCR11,Chemokine receptor X,CKRX,CRAM A,CRAM B,CRAMA,CRAMB,FLJ55815,HCR,MGC116710,MGC34104,Putative MCP 1 chemokine receptor,Putative MCP-1 chemokine receptor

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: WB,IF,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms C-C chemokine receptor-like 2,CCRL2,CCRL2,Chemokine (C-C motif) receptor like 2,Chemokine receptor CCR11,Chemokine receptor X,CKRX,CRAM A,CRAM B,CRAMA,CRAMB,FLJ55815,HCR,MGC116710,MGC34104,Putative MCP 1 chemokine receptor,Putative MCP-1 chemokine receptor
      Swissprot O00421
      Source Rabbit
      Reactivity Human
      Immunogen Synthesized peptide derived from the Internal region of human CCRL2
      Application WB,IF,ELISA
      Recommended dilution WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:20000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cell membrane.
      Tissue specificity Expressed abundantly in immunal tissues such as spleen, fetal liver, lymph node and bone marrow. Strong expression also in lung and heart. Expressed in almost all hematopoietic cells including monocytes, macrophages, PMNs, T-cells (both CD4+ and CD8+), monocyte-derived iDCs, NK cells, and CD34+ progenitor cells. B cells expressed isoform 1 but not isoform 2. Up-regulated on synovial neutrophils of rheumatoid arthritis patients.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located.CCRL2 (C-C Motif Chemokine Receptor Like 2) is a Protein Coding gene. Among its related pathways are Peptide ligand-binding receptors and Chemokine Superfamily Pathway: Human/Mouse Ligand-Receptor Interactions. GO annotations related to this gene include G-protein coupled receptor activity and chemokine receptor binding. An important paralog of this gene is CCR3.

      Images

      Western Blot analysis of HepG2 cells with CCRL2 Polyclonal Antibody.

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