CD130 Polyclonal Antibody

Uniprot: P40189
  • polyclonal antibody-Elabscience
  • polyclonal antibody-Elabscience
  • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30802

      Synonyms:CD130,CD130 antigen,CDw130,gp130,GP130 RAPS,IL 6R beta,IL-6 receptor subunit beta,IL-6R subunit beta,IL-6R-beta,IL-6RB,IL6 ST,IL6RB,IL6ST,Interleukin 6 receptor subunit beta,Interleukin receptor beta chain,Interleukin-6 receptor subunit beta,Interleukin-6 signal transducer,Membrane glycoprotein 130,Membrane glycoprotein gp130,Oncostatin M receptor,Oncostatin M receptor alpha subunit,Oncostatin-M receptor subunit alpha

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,IHC-p,IF,ELISA

      Lead Time: 2 daysWelcome to order from local distributors.

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      Overview

      Synonyms CD130,CD130 antigen,CDw130,gp130,GP130 RAPS,IL 6R beta,IL-6 receptor subunit beta,IL-6R subunit beta,IL-6R-beta,IL-6RB,IL6 ST,IL6RB,IL6ST,Interleukin 6 receptor subunit beta,Interleukin receptor beta chain,Interleukin-6 receptor subunit beta,Interleukin-6 signal transducer,Membrane glycoprotein 130,Membrane glycoprotein gp130,Oncostatin M receptor,Oncostatin M receptor alpha subunit,Oncostatin-M receptor subunit alpha
      Swissprot P40189
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Synthesized peptide derived from human CD130 around the non-phosphorylation site of Ser782.
      Application WB,IHC-p,IF,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Secreted and Cell membrane.
      Tissue specificity Found in all the tissues and cell lines examined. Expression not restricted to IL6 responsive cells.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize gp130 for initiating signal transmission. Binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. Does not bind IL6. May have a role in embryonic development (By similarity). The type I OSM receptor is capable of transducing OSM-specific signaling events.

      Images

      Western Blot analysis of 293T, COLO205 cells using CD130 Polyclonal Antibody at dilution of 1:500.

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