CD163 Polyclonal Antibody

Uniprot : Q86VB7
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-12773

      Synonyms:C163A,CD 163,CD163,CD163 antigen,CD163 molecule,Hemoglobin scavenger receptor,M130,M130 antigen precursor,Macrophage associated antigen,MM130,OTTHUMP00000238617,OTTHUMP00000238618,OTTHUMP00000238619,OTTHUMP00000238620,SCARI1,Scavenger receptor cysteine rich type 1 protein M130,sCD163,Soluble CD163

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms C163A,CD 163,CD163,CD163 antigen,CD163 molecule,Hemoglobin scavenger receptor,M130,M130 antigen precursor,Macrophage associated antigen,MM130,OTTHUMP00000238617,OTTHUMP00000238618,OTTHUMP00000238619,OTTHUMP00000238620,SCARI1,Scavenger receptor cysteine rich type 1 protein M130,sCD163,Soluble CD163
      Swissprot Q86VB7
      Source Rabbit
      Reactivity Human
      Immunogen Synthetic peptide of human CD163
      Application IHC(Detection kit: E-IR-R217),ELISA
      Recommended dilution IHC 1:25-1:100
      Concentration 0.9 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Membrane
      Tissue specificity Expressed in monocytes and mature macrophages such as Kupffer cells in the liver, red pulp macrophages in the spleen, cortical macrophages in the thymus, resident bone marrow macrophages and meningeal macrophages of the central nervous system. Expressed also in blood. Isoform 1 is the lowest abundant in the blood. Isoform 2 is the lowest abundant in the liver and the spleen. Isoform 3 is the predominant isoform detected in the blood.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

      Images

      polyclonal antibody-Elabscience

      Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using CD163 Polyclonal Antibody at dilution 1:30

      polyclonal antibody-Elabscience

      Immunohistochemistry of paraffin-embedded Human brain tissue using CD163 Polyclonal Antibody at dilution 1:30

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      MSDS for ELISA ISO 9001

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