CD172b Polyclonal Antibody

Uniprot: O00241
  • polyclonal antibody-Elabscience
  • polyclonal antibody-Elabscience
  • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30807

      Synonyms:SIRPB1,Signal-regulatory protein beta-1,SIRP-beta-1,CD172 antigen-like family member B,CD antigen CD172b

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms SIRPB1,Signal-regulatory protein beta-1,SIRP-beta-1,CD172 antigen-like family member B,CD antigen CD172b
      Swissprot O00241
      Source Rabbit
      Reactivity Human
      Immunogen Synthesized peptide derived from the Internal region of human CD172b
      Application WB,ELISA
      Recommended dilution WB 1:500-1:2000, ELISA 1:5000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Extracellular region or secreted,extracellular exosome,Plasma Membrane,integral component of Plasma Membrane,Other locations:secretory granule membrane
      Tissue specificity Detected in monocytes and dendritic cells.
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene.SIRPB1 (Signal Regulatory Protein Beta 1) is a Protein Coding gene. Diseases associated with SIRPB1 include Composite Lymphoma. Among its related pathways are Cell junction organization and Innate Immune System. An important paralog of this gene is SIRPA.

      Images

      Western Blot analysis of Hela cells with CD172b Polyclonal Antibody.

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