CD179b Polyclonal Antibody

    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30808

      Synonyms:IGLL1,IGL1,Immunoglobulin lambda-like polypeptide 1,CD179 antigen-like family member B,Ig lambda-5,Immunoglobulin omega polypeptide,Immunoglobulin-related protein 14.1,CD antigen CD179b,IGLC1,Ig lambda-1 chain C regions,IGLC2,Ig

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms IGLL1,IGL1,Immunoglobulin lambda-like polypeptide 1,CD179 antigen-like family member B,Ig lambda-5,Immunoglobulin omega polypeptide,Immunoglobulin-related protein 14.1,CD antigen CD179b,IGLC1,Ig lambda-1 chain C regions,IGLC2,Ig
      Swissprot P15814,P0CG04,P0CG05
      Source Rabbit
      Reactivity Human
      Immunogen Synthesized peptide derived from the N-terminal region of human CD179b.
      Application WB,ELISA
      Recommended dilution WB 1:500-1:2000, ELISA 1:10000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Extracellular region or secreted,blood microparticle,extracellular exosome,extracellular region,extracellular space,immunoglobulin complex, circulating,Plasma Membrane,external side of Plasma Membrane
      Tissue specificity Expressed only in pre-B-cells and a special B-cell line (which is surface Ig negative).1 Publication
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene.IGLL1 (Immunoglobulin Lambda Like Polypeptide 1) is a Protein Coding gene. Diseases associated with IGLL1 include Agammaglobulinemia 2 and Agammaglobulinemia, Non-Bruton Type. Among its related pathways are Cell surface interactions at the vascular wall and Primary immunodeficiency. An important paralog of this gene is IGLL5.

      Images

      Western Blot analysis of Hela cells using CD179b Polyclonal Antibody at dilution of 1:1000.

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