CD1E Polyclonal Antibody

Uniprot: P15812
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30810

      Synonyms:CD_antigen=CD1e,CD1A,CD1e,CD1e antigen,CD1E antigen,e polypeptide,CD1e molecule,CD1E,Differentiation antigen CD1-alpha-3,hCD1e,Leukocyte differentiation antigen,R2,R2G1,sCD1e,soluble,T-cell surface glycoprotein CD1e,T-cell surface glycoprotein CD1e,membrane-associated,T-cell surface glycoprotein CD1e,soluble

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms CD_antigen=CD1e,CD1A,CD1e,CD1e antigen,CD1E antigen,e polypeptide,CD1e molecule,CD1E,Differentiation antigen CD1-alpha-3,hCD1e,Leukocyte differentiation antigen,R2,R2G1,sCD1e,soluble,T-cell surface glycoprotein CD1e,T-cell surface glycoprotein CD1e,membrane-associated,T-cell surface glycoprotein CD1e,soluble
      Swissprot P15812
      Source Rabbit
      Reactivity Human
      Immunogen Synthesized peptide derived from the Internal region of human CD1e
      Application WB,ELISA
      Recommended dilution WB 1:500-1:2000, ELISA 1:10000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Lysosome lumen and Golgi apparatus membrane. Early endosome. Late endosome. Predominantly localized in the trans-Golgi network in immature dendritic cells, and as a cleaved, soluble protein in the lysosome lumen of mature dendritic cells.
      Tissue specificity Expressed on cortical thymocytes, dendritic cells, Langerhans cells, on certain T-cell leukemias, and in various other tissues.
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members. Many alternatively spliced transcript variants encoding different isoforms have been described. Additional transcript variants have been found; however, their biological validity has not been determined.CD1E (CD1e Molecule) is a Protein Coding gene. Diseases associated with CD1E include Mycobacterium Malmoense and Autoimmune Disease Of Central Nervous System. Among its related pathways are Tight junction and Hematopoietic cell lineage. GO annotations related to this gene include lipid binding and lipopeptide binding. An important paralog of this gene is CD1B.

      Images

      Western Blot analysis of HepG2 cells with CD1e Polyclonal Antibody.

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