CD21 Monoclonal Antibody

  • Pathological antibodies-Elabscience
    • Pathological antibodies-Elabscience
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    • Pathological antibodies-Elabscience
    • Pathological antibodies-Elabscience
      Catalog number:E-PA-3201

      Synonyms:Complement receptor type 2 ,Cr2,Complement C3d receptor,Epstein-Barr virus receptor,EBV receptor,CD antigen CD21

      Size:
      • 0.1mL
      • 0.2mL
      Qty:
      - +
      Price: Inquire

      Reactivity: Human

      Applications: IHC-p

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Background

      Background CD21 is also called the complement receptor 2 type (CR2) and EB virus receptor, is a member of the complement activation regulators family.CD21 is mainly distributed in mature B cells, dendritic cells in lymphoid follicles, and part of the T cells. The functions of CD21 include promoting proliferation of B cell, mediating transformation of EBV to B cells and participating in immune memory. It is mainly used for diagnosis of follicular cell tumors and study of regulation of immune complement activation.

      Overview

      Synonyms Complement receptor type 2 ,Cr2,Complement C3d receptor,Epstein-Barr virus receptor,EBV receptor,CD antigen CD21
      Swissprot P20023
      Source Mouse
      Reactivity Human
      Immunogen Full length protein from eukaryotic expression system.
      Application IHC-p
      Recommended dilution IHC 1:500
      Concentration 1mg/mL
      Clonality Monoclonal

      Properties

      Positive_control Tonsil
      Cellular localization Membrane
      Specificity This antibody detects endogenous levels of CD21
      Clone No. Clone:1G1
      Isotype IgG
      Purify Antigen affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃, Avoid freeze / thaw cycles
      Storage buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      Function Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation.Acts as a receptor for Epstein-Barr virus.

      Images

      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human tonsil tissue labeling CD21 Monoclonal Antibody with E-PA-3201 at dilution of 1:500. Heat induced epitope retrieval was performed by boiling the tissue sections in citrate buffer(PH6.0)for 20 minutes. Incubation with the primary antibody was performed for overnight at 4℃ followed by keeping at room temperature for 15mins. HRP conjugated Anti-Mouse secondary antibody was applied for 30 minutes at room temperature followed by DAB as chromogen, then counterstain with haematoxylin.
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