CD32-A Polyclonal Antibody

Uniprot: P12318
  • polyclonal antibody-Elabscience
  • polyclonal antibody-Elabscience
  • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30823

      Synonyms:CD32,CD32 antigen,CDw32,Fc fragment of IgG,low affinity IIa,receptor (CD32),Fc fragment of IgG,low affinity IIa,receptor for (CD32),Fc gamma RII a,Fc gamma RIIa,Fc-gamma RII-a,Fc-gamma-RIIa,FCG2,FCG2A,FcGR,FCGR2,FCGR2A,FCGR2A1,FcRII a,FcRII-a,IGFR2,IgG Fc receptor II a,IgG Fc receptor II-a,Immunoglobulin G Fc receptor II,low affinity immunoglobulin gamma Fc region receptor II a,Low affinity immunoglobulin gamma Fc region receptor II-a

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms CD32,CD32 antigen,CDw32,Fc fragment of IgG,low affinity IIa,receptor (CD32),Fc fragment of IgG,low affinity IIa,receptor for (CD32),Fc gamma RII a,Fc gamma RIIa,Fc-gamma RII-a,Fc-gamma-RIIa,FCG2,FCG2A,FcGR,FCGR2,FCGR2A,FCGR2A1,FcRII a,FcRII-a,IGFR2,IgG Fc receptor II a,IgG Fc receptor II-a,Immunoglobulin G Fc receptor II,low affinity immunoglobulin gamma Fc region receptor II a,Low affinity immunoglobulin gamma Fc region receptor II-a
      Swissprot P12318
      Source Rabbit
      Reactivity Human
      Immunogen Synthesized peptide derived from the C-terminal region of human CD32-A
      Application WB,ELISA
      Recommended dilution WB 1:500-1:2000, ELISA 1:20000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cell membrane.
      Tissue specificity Found on monocytes, neutrophils and eosinophil platelets.
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background CD32 (also designated Fc gamma RII) is a low affinity receptor for the Fc fragment of aggregated IgG (1,2). CD32 is responsible for the clearance of immunocomplexes by macrophages and also plays an important role in the regulation of antibody production by B cells (1-4). IgG can noncooperatively bind either one or two highly glycosylated CD32 molecules, and this binding delivers.3 a negative signal for B cells (1,2,5). CD32 exists as several isoforms that are produced by alternative splicing of three distinct genes, A, B, and C (2,6). These isoforms are designated FcgRIIA, FcgRIIB1, FcgRIIB3, and FcgRIIC (1,2,6). All isoforms are present on monocytes, placental trophoblasts and endothelial cells (1,6). In addition, the FcgRIIB forms are present on B lymphocytes, and the FcgRIIA and FcgRIIC forms are found on neutrophils (1,6).

      Images

      Western Blot analysis of Hela cells with CD32-A Polyclonal Antibody.

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